| CODE | CSA5008 | |||||||||
| TITLE | Introduction to Bioinformatics | |||||||||
| UM LEVEL | 05 - Postgraduate Modular Diploma or Degree Course | |||||||||
| MQF LEVEL | Not Applicable | |||||||||
| ECTS CREDITS | 6 | |||||||||
| DEPARTMENT | Intelligent Computer Systems | |||||||||
| DESCRIPTION | This study-unit deals with the storage, processing, retrieval, analysis, and understanding of biological information. This information is usually protein or DNA sequences. This aim of the unit is to show that analysis of these sequences leads to a much fuller understanding of many biological processes allowing drug designers, scientists, pharmaceutical and biotechnology companies to determine, for example, new drug targets or to predict of a particular drug is applicable to all patients. Students will be introduced to the basic concepts behind Bioinformatics and Computational Biology tools The first part of the study-unit deals with string processing and analysis algorithms. Topics covered include: • Formal Languages; • String edit distance; • Suffix trees; • Multiple string comparison; • Indexing; • String searching; • String Matching. The second part of the study-unit deals with applying the above algorithms in Bioinformatics. Topics covered include: • Protein and DNA sequences; • Alignment algorithms; • Sequence classification; • AI techniques applied to sequence analysis; • The protein folding prediction problem. Textbooks: • Algorithms on Strings, Trees, and Sequences. Dan Gusfield. • Protein Bioinformatics: An Algorithmic Approach to Sequence and Structure Analysis. Eidhammer, Jonassen, and Taylor. |
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| STUDY-UNIT TYPE | Lecture | |||||||||
| METHOD OF ASSESSMENT |
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| LECTURER/S | John M. Abela |
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The University makes every effort to ensure that the published Courses Plans, Programmes of Study and Study-Unit information are complete and up-to-date at the time of publication. The University reserves the right to make changes in case errors are detected after publication.
The availability of optional units may be subject to timetabling constraints. Units not attracting a sufficient number of registrations may be withdrawn without notice. It should be noted that all the information in the description above applies to study-units available during the academic year 2023/4. It may be subject to change in subsequent years. |
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