University of Malta
 

Research & Publications
UOM Main Page
 
 
 
Apply - Admissions 2016
Newspoint
Malta Medical Journal
MPS

Academic Staff Research & Publications

Prof G DiGiovanni

BOOKS (Editor)

I GIOVANNI G. (In Preparation) Neurotransmitter-Dopamine Interactions: Function, Dysfunction, and Therapies. Wiley-Blackwell, John Wiley & Sons. In preparation. 111994922X

GUIRD B. DI GIOVANNI G. (2016). “5-HT2A Receptors in the CNS” Springer, New York.

MILLIGAN G., DI GIOVANNI G., HERRICK-DAVIS K. “G Protein-Coupled Receptor Dimer” Springer, New York.

ERRINGTON A, DI GIOVANNI G., CRUNELLI V., (2014). “Extrasynaptic GABAA receptor in the physiopatahology of the CNS” Springer, New York.

DI GIOVANNI G. DI MATTEO V. (2013) “Microdialysis Techniques in Neuroscience” Springer Protocols, Springer, New York. SBN 978-1-62703-173-8

DI GIOVANNI G. (2012) Nicotine Addiction: Prevention, Health Effects and Treatment Options. Nova Publishers, New York. ISBN 978-1620812907

DI GIOVANNI G., ESPOSITO E. DI MATTEO V., (2011). “5-HT2C Receptors in the Pathophysiology of CNS Disease” Springer, New York.

DI GIOVANNI G., DI MATTEO V., ESPOSITO E. (2009) “Birth, Life and Death of Dopaminergic Neurons in the Substantia Nigra” Journal of Neural Transmission Supplementa, 73. Springer-Werlag, Vienna.

DI GIOVANNI G., DI MATTEO V., ESPOSITO E. (2008) “Serotonin-Dopamine Interaction: Experimental and Therapeutic Evidence, Progress in Brain Research, 172. Elsevier, Netherlands.

DI GIOVANNI G. (2007) "The Basal Ganglia Pathophysiology: Recent Advances" Research Signpost, India. ISBN: 8178952688

FULL PAPERS IN PEER REVIEWED JOURNALS

VENZI M, DAVID F, BELLET J, CAVACCINI A, BOMBARDI C, CRUNELLI V, DI GIOVANNI G. (2016) Role for Serotonin2A (5-HT2A) and 2C (5-HT2C) Receptors in Experimental Absence Seizures. NEUROPHARMACOLOGY In Press

GORAN ŠIMIĆ, MIRJANA BABIĆ LEKO, SELINA WRAY, CHARLES HARRINGTON, IVANA DELALLE, NATAŠA JOVANOV-MILOŠEVIĆ, DANIRA BAŽADONA, LUC BUÉE, ROHAN DE SILVA, GIUSEPPE DI GIOVANNI, CLAUDE WISCHIK, PATRICK R. HOF: Monoaminergic Neuropathology in Alzheimer's. PROGRESS IN NEUROBIOLOGY In Press.

ŠIMIĆ G, BABIĆ LEKO M, WRAY S, HARRINGTON C, DELALLE I, JOVANOV-MILOŠEVIĆ N, BAŽADONA D, BUÉE L, DE SILVA R, DI GIOVANNI G, WISCHIK C, HOF PR. (2016) Tau Protein Hyperphosphorylation and Aggregation in Alzheimer's Disease and Other Tauopathies, and Possible Neuroprotective Strategies. BIOMOLECULES. Jan6;6(1).

SCHIAVONE S, MHILLAJ E, NERI M, MORGESE MG, TUCCI P, BOVE M, VALENTINO M, DI GIOVANNI G, POMARA C, TURILLAZZI E, TRABACE L, CUOMO V. (2016) Early Loss of Blood-Brain Barrier Integrity Precedes NOX2 Elevation in the Prefrontal Cortex of an Animal Model of Psychosis. MOL NEUROBIOL. Feb 24. [Epub ahead of print] PubMed PMID: 26910819.

SALVADÈ A, D'ANGELO V, DI GIOVANNI G, TINKHAUSER G, SANCESARIO G, STÄDLER C, MÖLLER JC, STEFANI A, KAELIN-LANG A, GALATI S. (2016) Distinct roles of cortical and pallidal β and γ frequencies in hemiparkinsonian and dyskinetic rats. EXP NEUROL. 275 Pt 1:199-208.

DE DEURWAERDÈRE P, DI GIOVANNI G. (2016) Serotonergic Modulation of the Activity of Mesencephalic Dopaminergic Systems. PROGRESS IN NEUROBIOLOGY In Press.

DI GIOVANNI G., DE DEURWAERDÈRE P. (2016) New therapeutic opportunities for 5-HT2C receptor ligands in neuropsychiatric disorders. PHARMACOLOGY AND THERAPEUTICS 157:125-162

CRUNELLI V, DI GIOVANNI G. (2015) Differential Control by 5-HT and 5-HT1A, 2A, 2C Receptors of Phasic and Tonic GABAA Inhibition in the Visual Thalamus. CNS NEUROSCIENCE AND THERAPEUTICS. 21(12): 967–970.

NAVAILLES S, DI GIOVANNI G. DE DEURWAERDÈRE P. (2015) The 5-HT4 Agonist Prucalopride Stimulates L-DOPA-Induced Dopamine Release in Restricted Brain Regions Of The Hemiparkinsonian Rat In Vivo. CNS NEUROSCIENCE & THERAPEUTICS. 21(9):745-7. doi: 10.1111/cns.12436.

CASARRUBEA M, FAULISI F, CATERNICCHIA F, SANTANGELO A, DI GIOVANNI G, BENIGNO A, MAGNUSSON MS, CRESCIMANNO G. Temporal patterns of rat behaviour in the central platform of the elevated plus maze. Comparative analysis between male subjects of strains with different basal levels of emotionality. J NEUROSCI METHODS. 2015 Aug 3. pii: S0165-0270(15)00279-4. doi: 10.1016/j.jneumeth.2015.07.024.

GUIARD BP, DI GIOVANNI G. Central serotonin-2A (5-HT2A) receptor dysfunction in depression and epilepsy: the missing link? FRONT PHARMACOL. 2015 Mar 17;6:46.

VENZI M, DI GIOVANNI G, CRUNELLI V. A critical evaluation of the gamma-hydroxybutyrate (GHB) model of absence seizures. CNS NEUROSCI THER. 2015 Feb;21(2):123-40. doi: 10.1111/cns.12337.

CASARRUBEA M, DAVIES C, FAULISI F, PIERUCCI M, COLANGELI R, PARTRIDGE L, CHAMBERS S, CASSAR D, VALENTINO M, MUSCAT R, BENIGNO A, CRESCIMANNO G, DI GIOVANNI G. (2015) Acute Nicotine Induces Anxiety and Disrupt Temporal Pattern Organization of Rat Exploratory Behavior in Hole-Board: A Role for the Lateral Habenula? FRONTIERS IN CELLULAR NEUROSCIENCE. 9:197. doi: 10.3389/fncel.2015.00197.

D'ADAMO MC, GALLENMUELLER C, SERVETTINI I, HARTL E, TUCKER S, ARNING L, BISKUP S, GROTTESI A, GUGLIELMI L, IMBRICI P, BERNASCONI P, DI GIOVANNI G, FRANCIOLINI F, CATACUZZENO L, PESSIA M, KLOPSTOCK T. (2015) Novel phenotype associated with a mutation in the KCNA1(Kv1.1) gene. FRONTIERS IN PHYSIOLOGY. 5:525. doi: 10.3389/fphys.2014.00525.

CASARRUBEA M, JONSSON GK, FAULISI F, SORBERA F, DI GIOVANNI G, BENIGNO A, CRESCIMANNO G, MAGNUSSON MS. (2014) T-pattern analysis for the study of temporal structure of animal and human behavior: A comprehensive review. J NEUROSCI METHODS. 239: 34–46.

GODAR SC, MOSHER LJ, DI GIOVANNI G, BORTOLATO M. (2014) Animal models of tic disorders: A translational perspective. J NEUROSCI METHODS. 238:54-69.

TAYLOR H, SCHMIEDT JT, CARÇAK N, ONAT F, DI GIOVANNI G, LAMBERT R, LERESCHE N, CRUNELLI V, DAVID F. (2014) Investigating local and long-range neuronal network dynamics by simultaneous optogenetics, reverse microdialysis and silicon probe recordings in vivo. J NEUROSCI METHODS. 235:83-91.

RAMSAY RR, DI GIOVANNI G. (2014) Interdisciplinary chemical approaches for neuropathology. CNS NEUROSCIENCE & THERAPEUTICS. 20(7):571-3.

NAVAILLES S, MILAN L, KHALKI H, DI GIOVANNI G, LAGIÈRE M, DE DEURWAERDÈRE P. (2014) Noradrenergic Terminals Regulate l-DOPA-derived Dopamine Extracellular Levels in a Region-dependent Manner in Parkinsonian Rats. CNS NEUROSCIENCE & THERAPEUTICS. doi: 10.1111/cns.12275.

NAVAILLES S, DI GIOVANNI G, DE DEURWAERDÈRE P. (2014) Predicting Dopaminergic Effects of L-DOPA in the Treatment for Parkinson's Disease. CNS NEUROSCIENCE & THERAPEUTICS. doi: 10.1111/cns.12252.

ORBAN G, BOMBARDI C, MARINO GAMMAZZA A, COLANGELI R, PIERUCCI M, POMARA C, PESSIA M, BUCCHIERI F, BENIGNO A, SMOLDERS I, DE DEURWAERDÈRE P, DI GIOVANNI G. (2014) Role(s) of the 5-HT2C Receptor in the development of Maximal Dentate Activation in the Hippocampus of anesthetized rats. CNS NEUROSCIENCE & THERAPEUTICS 20 (7):651-61.

DI GIOVANNI G, GARCÍA I, COLANGELI R, PIERUCCI M, RIVADULLA ML, SORIANO E, CHIOUA M, DELLA CORTE L, YÁÑEZ M, FALL Y, MARCO-CONTELLES J. (2014) Synthesis and Pharmacological Evaluation of MAO Inhibitors N-(Furan-2-ylmethyl)-N-prop-2-yn-1-amine Derivatives as Potential Drugs for the Treatment of Alzheimer’s Disease. CNS NEUROSCIENCE & THERAPEUTICS 20 (7):633-40.

AOURZ N, PORTELLI J, COPPENS J, DE BUNDEL D, VAN EECKHAUT A, DI GIOVANNI G, MICHOTTE Y, SMOLDERS I. (2014) Cortistatin-14 mediates its anticonvulsant effects via sst2 and sst3 but not ghrelin receptors. CNS NEUROSCIENCE & THERAPEUTICS 20(7):662-70.

MIFSUD G, ZAMMIT C, MUSCAT R, DI GIOVANNI G, VALENTINO M. (2014) Oligodendrocyte pathophysiology and treatment strategies in cerebral ischemia. CNS NEUROSCIENCE & THERAPEUTICS 20(7):603-12.

CRUNELLI V. DI GIOVANNI G. (2014) Monoamine Modulation of Tonic GABAA inhibition. REVIEW IN NEUROSCIENCES. 25(2):195-206.

DAVID F, SCHMIEDT J, TAYLOR H, ORBAN G, DI GIOVANNI G, UEBELE VN, RENGER JJ, LAMBERT RC, LERESCHE N, CRUNELLI V. (2013) Essential Thalamic Contribution To Slow Waves of Natural Sleep. JOURNAL NEUROSCIENCE 33(50):19599-610

CONNELLY B., ERRINGTON A. C., DI GIOVANNI G., CRUNELLI V. (2013) Metabotropic regulation of extrasynaptic GABAA receptors. FRONTIER NEURAL CIRCUITS 7:171. doi: 10.3389/fncir.2013.00171

D'ADAMO M.C., SERVETTINI I., GUGLIELMI L., DI MATTEO, V., DI MAIO R., DI GIOVANNI, G., PESSIA M. (2013) 5-HT2 receptors-mediated modulation of voltage-gated K+ channels and neurophysiopathological correlates. EXPERIMANTAL BRAIN RESEARCH, 230(4):453-462.

BOMBARDI C., DI GIOVANNI G. (2013) Functional Anatomy of 5-HT2A Receptors in the Amygdala and Hippocampal Complex: Relevance to Memory. Functions. EXPERIMANTAL BRAIN RESEARCH 230(4):427-39

ORBAN G., PIERUCCI M., BENIGNO A., GALATI S., PESSIA M., VALENTINO M., MUSCAT R., DI GIOVANNI G. (2013) High dose of 8-OH-DPAT decreases Maximal Dentate Gyrus Activation and facilitates Granular Cell plasticity in Vivo" (DOI: 10.1007/s00221-013-3594-1. EXPERIMANTAL BRAIN RESEARCH. 230(4):441-51.

BOULOUGOURIS V, MALOGIANNIS I, LOCKWOOD G, ZERVAS I, DI GIOVANNI G. (2013) Serotonergic modulation of suicidal behaviour: integrating preclinical data with clinical practice and psychotherapy. EXP BRAIN RES. 230(4):605-24

MARIA CRISTINA D'ADAMO, LUIGI CATACUZZENO, GIUSEPPE DI GIOVANNI, FABIO FRANCIOLINI, MAURO PESSIA. (2013) K+ CHANNELEPSY: progress in the neurobiology of potassium channels and epilepsy. FRONTIER CELL NEUROSCIENCE 7:134.

JOERI VAN LIEFFERINGE, ANN MASSIE, JEANELLE PORTELLI, GIUSEPPE DI GIOVANNI, ILSE SMOLDERS. (2013) Are vesicular neurotransmitter transporters potential treatment targets for temporal epilepsy? FRONTIER CELL NEUROSCIENCE 7:139.

PROSPERETTI C., DI GIOVANNI G., STEFANI A., BASSETTI C. L., MÖLLER J. C., GALATI S. (2013) Acute Nigro-Striatal Blockade Alters Cortico-Striatal Encoding: An In Vivo Electrophysiological Study. EXPERIMENTAL NEUROLOGY 247:730-736

YAGÜE JG, CAVACCINI A, ERRINGTON AC, CRUNELLI V, DI GIOVANNI G. (2013) Dopaminergic Modulation of Tonic but not Phasic GABAA Inhibition in the Ventrobasal Thalamus of Wistar and GAERS rats. EXPERIMENTAL NEUROLOGY 247, 1-7.

CONNELLY B., FYSON S. J., ERRINGTON A. C., MCCAFFERTY C., COPE D. W., DI GIOVANNI G., CRUNELLI V. (2013) GABAB Receptors Regulate Extrasynaptic GABAA Receptors. JOURNAL OF NEUROSCIENCE 33(9), 3780-5378.

BORTOLATO M., PIVAC N., MÜCK-ŠELER D., NIKOLAC PERKOVIC M., PESSIA M., DI GIOVANNI G. (2013) The Role of the Serotonergic System at the Interface of Aggression and Suicide. NEUROSCIENCE 236, 160-185.

BRUNETTI O, IMBRICI P, BOTTI FM, PETTOROSSI VE, D'ADAMO MC, VALENTINO M, ZAMMIT C, MORA M, GIBERTINI S, DI GIOVANNI G, MUSCAT R, PESSIA M. (2012) Kv1.1 knock-in ataxic mice exhibit spontaneous myokymic activity exacerbated by fatigue, ischemia and low temperature. NEUROBIOLOGY OF DISEASE, 47(3), 310-321.

DI GIOVANNI G, PESSIA M, DI MAIO R. (2012) Redox Sensitivity of Tyrosine Hydroxylase Activity and Expression in Dopaminergic Dysfunction. CNS NEUROLOLOGICAL DISORDERS DRUG TARGETS, 11(4), 419-429.

DI GIOVANNI G (2012) Does Central Serotonin2C Receptors still have New Therapeutic Potential? BIOCHEM PHYSIOL 1:e101. doi:10.4172/bcpc.1000e101

DI GIOVANNI G, ERRINGTON AC, CRUNELLI V. (2011) Pathophysiological Role of Extrasynaptic GABAA Receptors in Typical Absence Epilepsy. MALTA MEDICAL JOURNAL. 23(3), online http://www.um.edu.mt/umms/mmj/showpdf.php?article=326

ZAMMIT C, MUSCAT R, DI GIOVANNI G, PIERUCCI M, VALENTINO M. (2011) Vulnerability of white matter to ischemia varies during development. MALTA MEDICAL JOURNAL 23(3), online http://www.um.edu.mt/umms/mmj/PDF/333.pdf

PIERUCCI M, PITRUZZELLA A, VALENTINO M, MUSCAT R, BENIGNO A, DI GIOVANNI G (2011) Lateral Habenular Contribution in Nicotine Addiction: Focous on Dopamine, GABA and Serotonin Interactions. MALTA MEDICAL JOURNAL 23(3), online http://www.um.edu.mt/umms/mmj/showpdf.php?article=331

PIERUCCI M, GALATI S, VALENTINO M, DI MATTEO V, BENIGNO A, MUSCAT R, PITRUZZELLA A, DI GIOVANNI G (2011) Nitric Oxide Modulation of the Basal Ganglia Circuitry: Therapeutic Implication for Parkinson’s Disease and Other Motor Disorders. CNS & NEUROLOGICAL DISORDERS. DRUG TARGETS, 10 (7):777-791.

DI GIOVANNI G. (2011) Nitric Oxide: Implications for the Etiology & Treatment of Central Nervous System Disorders. CNS & NEUROLOGICAL DISORDERS. DRUG TARGETS, 10 (7): 764-765.

ERRINGTON A.C., DI GIOVANNI G., CRUNELLI V. COPE D.W. (2011) mGluR control of interneuron output regulates feedforward tonic GABAA inhibition in the visual thalamus. JOURNAL OF NEUROSCIENCE. 31(23):8669-80.

GALATI S., D’ANGELOV., OLIVOLA E., MARZETTI F, DI GIOVANNI G., STANZIONE P., STEFANI A. (2010) Acute Inactivation of the Medial Forebrain Bundle Imposes Oscillations in the SNr: A Challenge for the 6-OHDA Model? EXPERIMENTAL NEUROLOGY. 225, 294-301.

GALATI S., DI GIOVANNI G. (2010) Neuroprotection in Parkinson’s Disease: A Realistic Goal? CNS NEUROSCIENCE AND THERAPEUTICS. 16(6), 327-9.

DI MATTEO V., PIERUCCI M., BENIGNO A., CRESCIMANNO G., ESPOSITO E., DI GIOVANNI G. (2010) Critical role of Nitric Oxide on Nicotine-Induced Hyperactivation of Dopaminergic Nigrostriatal System: an Electrophysiological and Neurochemical Study in Rats. CNS NEUROSCIENCE AND THERAPEUTICS. 16 (3), 127-136.

DI GIOVANNI G., ESPOSITO E., DI MATTEO V. (2010) Role of Serotonin in Central Dopamine Dysfunction. CNS NEUROSCIENCE AND THERAPEUTICS. 16, (3) 179-194.

COPE D.W., DI GIOVANNI G., ORBAN G., FYSON S.J., ERRINGTON A.C., LORINCZ M.L., GOULD T.M., CARTER D.A., CRUNELLI V. (2009) Enhanced tonic GABAA inhibition is required in typical absence epilepsy. NATURE MEDICINE. 15(12), 1392-1398.

DI GIOVANNI G. (2009) A Diet for the Dopaminergic Neurons? JOURNAL NEURALTRANSMISSION SUPPLEMENTA.73, 317-332.

DI GIOVANNI G. and SHI W-X (2009) Effects of Scopolamine on Dopamine Neurons in the Substantia Nigra: Role of the Pedunculopontine Tegmental Nucleus. SYNAPSE. 63(8), 673-680.

DI MATTEO V., PIERUCCI M., BENIGNO A., ORBÁN G., CRESCIMANNO G., ESPOSITO E., DI GIOVANNI G. (2009) Electrophysiological and Neurochemical Characterization of 7-Nitroindazole and Molsidomine Acute and Sub-Chronic Administration Effects in the Dopaminergic Nigrostriatal System in Rats. JOURNAL NEURALTRANSMISSION SUPPLEMENTA. 73, 173-182.

ABDALLAHT L., BONASERA S.J., HOPF F.W., O’DELLF L., GIORGETTI M., JONGSMAS M., CARRAT S., PIERUCCI M., DI GIOVANNI G., ESPOSITO E., PARSONS L.H., BONCI A., TECOTT L.H. (2009) Impact of serotonin 2C receptor null mutation on physiology and behavior associated with nigrostriatal dopamine pathway function. JOURNAL OF NEUROSCIENCE. 29(25), 8156-8165.

DI GIOVANNI G., ESPOSITO E., DI MATTEO V. (2009) In Vivo Microdialysis in Parkinson’s Research. JOURNAL NEURALTRANSMISSION SUPPLEMENTA. 73, 223-243.

DI MATTEO V., PIERUCCI M., DI GIOVANNI G., DRAGANI L.K., MURZILLI S., POGGI A. AND ESPOSITO E. (2009) Intake of Tomato-Enriched Diet Protects from 6-Hydroxydopamine-Induced Degeneration of Rat Nigral Dopaminergic Neurons. JOURNAL NEURALTRANSMISSION SUPPLEMENTA. 73, 333-341.

PIERUCCI M., DI MATTEO V., BENIGNO A., CRESCIMANNO G., ESPOSITO E., DI GIOVANNI G. (2009) Involvement of Nitric Oxide In 6-OHDA-Induced Neurodegeneration: An Ex Vivo Study. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 1155, 316-323.

BALOSSO S., RAVIZZA T., PIERUCCI M., CALCAGNO E., INVERNIZZI R., DI GIOVANNI G., ESPOSITO E., VEZZANI A. (2009) Molecular and functional interactions between tumor necrosis factor-alpha receptors and the glutamatergic system in the mouse hippocampus: Implications for seizure susceptibility. NEUROSCIENCE. 161(1), 293-300.

DI MATTEO V., PIERUCCI M., BENIGNO A., CRESCIMANNO G., ESPOSITO E., DI GIOVANNI G. (2009) The Unilateral Nigral Lesion Induces Dramatic Bilateral Modification In Rat Brain Monoamine Levels: A Neurochemical Study. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 1155, 309-315.

DI GIOVANNI G., DI MATTEO V., ESPOSITO E. (2008) Serotonin and Dopamine Interaction: An Overview. PROGRESS IN BRAIN RESEARCH. 172, 3-6.

DI MATTEO V., DI GIOVANNI G., PIERUCCI M., ESPOSITO E. (2008) 5-HT/DA Interaction: Neurochemical Evidences. PROGRESS IN BRAIN RESEARCH. 172, 7-44.

DI GIOVANNI G., DI MATTEO V., PIERUCCI M., ESPOSITO E. (2008) 5-HT/DA Interaction: Electrophysiological Evidences. PROGRESS IN BRAIN RESEARCH. 172, 45-70.

DI MATTEO V., PIERUCCI M., ESPOSITO E., CRESCIMANNO G., BENIGNO A., DI GIOVANNI G. (2008) Serotonin Modulation of the Basal Ganglia Circuitry: Therapeutic Implication for Parkinson’s Disease and Other Motor Disorders. PROGRESS IN BRAIN RESEARCH. 172. 423-460.

DI GIOVANNI G. Will it Ever Become Possible to Prevent Dopaminergic Neuronal Degeneration? (2008) CNS & NEUROLOGICAL DISORDERS. DRUG TARGETS. 7(1), 28-44.

ESPOSITO E., DI MATTEO V, DI GIOVANNI G. (2007). Death in the substantia nigra: a motor tragedy. EXPERT REVIEW OF NEUROTHERAPEUTICS. 7(6), 677-697.

INVERNIZZI R.W., PIERUCCI M., CALCAGNO E., DI GIOVANNI G., DI MATTEO V., BENIGNO A., ESPOSITO E. (2007). Selective Activation of Serotonin2C Receptors Stimulates GABA-ergic Function in the Rat Substantia Nigra Pars Reticulata: A Combined in Vivo Electrophysiological and Neurochemical Study. NEUROSCIENCE. 144 (4), 1523-1535.

DI MATTEO V, PIERUCCI M, DI GIOVANNI G., BENIGNO A, ESPOSITO E. (2007). The Neurobiological Bases for the Pharmacotherapy of Nicotine Addiction. CURRENT PHARMACEUTICAL DESIGN. 13(12), 1269-1284.

 DI GIOVANNI G. New Serotonin and Dopamine ligands for the treatment of neuropsychiatric disorders (2008) CURRENT TOPICS IN MEDICINAL CHEMISTRY, 8(12), 1-3.

DI MATTEO V, ESPOSITO E, DI GIOVANNI G. (2008). Neurodegenerative disorders: from molecules to man (part 2). CNS & NEUROLOGICAL DISORDERS. DRUG TARGETS. 7(1), 1-2.

DI MATTEO V, ESPOSITO E, DI GIOVANNI G. (2007). Neurodegenerative disorders: from molecules to man (part 1). CNS & NEUROLOGICAL DISORDERS. DRUG TARGETS. 6(6), 375-376.

ESPOSITO E, DI MATTEO V, BENIGNO A, PIERUCCI M, CRESCIMANNO G, DI GIOVANNI G. (2007). Non-steroidal anti-inflammatory drugs in Parkinson’s disease. EXPERIMENTAL NEUROLOGY. 205(2), 295-312.

DI MATTEO V., BENIGNO A., PIERUCCI M., GIULIANO D.A., CRESCIMANNO G., ESPOSITO E., DI GIOVANNI G. (2006). 7-Nitroindazole protects striatal dopaminergic neurons from MPP+-induced degeneration: an in vivo microdialysis study. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 1089 (1), pp. 462–471.

DI MATTEO V., PIERUCCI M., DI GIOVANNI G., DI SANTO A., BENIGNO A., ESPOSITO E. (2006). Aspirin protects striatal dopaminergic neurons from neurotoxin-induced degeneration: an in vivo microdialysis study. BRAIN RESEARCH. vol. 1095 (1), pp. 167-177.

DI GIOVANNI G., DI MATTEO V, PIERUCCI M, BENIGNO A, ESPOSITO E. (2006). Central Serotonin2C Receptor: From Physiology to Pathology. CURRENT TOPICS IN MEDICINAL CHEMISTRY. vol. 6 (18), pp. 1909-1925.

DI GIOVANNI G., DI MATTEO V., PIERUCCI M., BENIGNO A., ESPOSITO E. (2006). Serotonin Involvement in the Basal Ganglia Pathophysiology: Could the 5-HT2C Receptor be a New Target for Therapeutic Strategies? CURRENT MEDICINAL CHEMISTRY. vol. 13 (25), pp. 3069-3081.

FERRARO G., SARDO P., DI GIOVANNI G., FILECCIA R., LA GRUTTA V. (2004). CCK-8S systemic administration blocks the 7-nitroindazole-induced effects on the EEG of striatum and globus pallidus: a FFT analysis in the rat. IN VIVO. vol. 18 (3), pp. 317-323.

FERRARO G., SARDO P., DI GIOVANNI G., R. DI MAIO, LA GRUTTA V. (2003). CCK-Nitric oxide interaction in rat cortex, striatum and-pallidum. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY. C. TOXICOLOGY & PHARMACOLOGY. vol. 135, pp. 425-433.

DI GIOVANNI G., FERRARO G., SARDO P., GALATI S., ESPOSITO E., LA GRUTTA V. (2003). Nitric Oxide Modulates Striatal Neuronal Activity via Soluble Guanylate Cyclase: An in vivo Microiontophoretic Study in rats. SYNAPSE. vol. 48, pp. 100-107.

SARDO P., FERRARO G., DI GIOVANNI G., LA GRUTTA V. (2003). Nitric oxide-induced inhibition on striatal cells and excitation on globus pallidus neurons: a microiontophoretic study in the rat. NEUROSCIENCE LETTERS. vol. 343, pp. 101-104.       

DI MATTEO V., CACCHIO M., DI GIULIO C., DI GIOVANNI G., ESPOSITO E. (2002). Biochemical evidence that the atypical antipsychotic drugs clozapine and risperidone block 5-HT(2C) receptors in vivo. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR. vol. 71, pp. 607-613.       

SARDO P., FERRARO G., DI GIOVANNI G., GALATI S., LA GRUTTA V. (2002). Influence of nitric oxide on the spontaneous activity of globus pallidus neurones in the rat. JOURNAL OF NEURAL TRANSMISSION. vol. 109, pp. 1373-1389.       

SARDO P., FERRARO G., DI GIOVANNI G., GALATI S., LA GRUTTA V. (2002). Inhibition of nitric oxide synthase influences the activity of striatal neurons in the rat. NEUROSCIENCE LETTERS. vol. 325, pp. 179-182

FERRARO G., SARDO P., DI GIOVANNI G., GALATI S., LA GRUTTA V. (2002). Nitric oxide and cortico-strito-pallidal motor circuitry: quantitatve EEG analysis of surface and depth recordings. NEUROSCIENCE RESEARCH COMMUNICATIONS. vol. 30, pp. 121-133.       

DI GIOVANNI G., DI MATTEO V., ESPOSITO E. (2002). Serotonin/dopamine interaction - Focus on 5-HT2C receptor a new target of psychotropic drugs. INDIAN JOURNAL OF EXPERIMENTAL BIOLOGY. vol. 40, pp. 1-9.       

DI GIOVANNI G., DI MATTEO V., LA GRUTTA V., ESPOSITO E. (2001). m-Chlorophenylpiperazine, an unselective serotonin2C receptor agonist, excites non-dopaminergic neurons in the rat Substantia Nigra and Ventral Tegmental Area. NEUROSCIENCE. vol. 103, pp. 111-116.       

DI MATTEO V., DI MASCIO M., DI GIOVANNI G., ESPOSITO E. (2000). Acute administration of amitriptyline and mianserin increases dopamine release in the rat nucleus accumbens: possible involvement of serotonin2C receptors. PSYCHOPHARMACOLOGY. vol. 150, pp. 45-51.       

DI MATTEO V., DI GIOVANNI G., DI MASCIO M., ESPOSITO E. (2000). Biochemical an electrophysiological evidence that RO 60-0175 inhibits mesolimbic dopaminergic function through serotonin2C receptors. BRAIN RESEARCH. vol. 865, pp. 85-90.       

DI MATTEO V., DI GIOVANNI G., DI MASCIO M., ESPOSITO E. (2000). Effect of acute administration of Hypericum Perforatum-C02 extract on dopamine and serotonin release in the rat central nervous system. PHARMACOPSYCHIATRY. vol. 33, pp. 14-18.       

DI GIOVANNI G., V. DI MATTEO, M. DI MASCIO, ESPOSITO E. (2000). Preferential modulation of mesolimbic vs nigostriatal dopaminergic function by serotonin2C/2B receptors agonist: a combined in vivo electrophisyological and microdialysis study. SYNAPSE. vol. 35, pp. 53-61.       

DI MATTEO V., DI GIOVANNI G., ESPOSITO E. (2000). SB 242084, A SELECTIVE SEROTONIN2C RECEPTORS ANTAGONIST. CNS DRUG REVIEWS. vol. 6, pp. 195-205.       

DI MASCIO M., DI GIOVANNI G., DI MATTEO V., ESPOSITO E. (1999). Decreased chaos of midbrain dopaminergic neurons after serotonin denervation. NEUROSCIENCE. vol. 92, pp. 237-243.       

DI MASCIO M., DI GIOVANNI G., DI MATTEO V., ESOSITO E. (1999). Reduced chaos of interspike interval of midbrain dopaminergic neurons in aged rats. NEUROSCIENCE. vol. 89, pp. 1003-1008.       

DI MATTEO V., DI GIOVANNI G., DI MASCIO M., ESPOSITO E. (1999). SB 242084, a selective serotonin2C receptors antagonist, increases dopaminergic transmission in the mesolimbic system. NEUROPHARMACOLOGY. vol. 38, pp. 1195-1205 ISSN: 0028-3908.       

DI GIOVANNI G., DE DEURWAERDERE P., DI MASCIO M., DI MATTEO V., ESPOSITO E., SPAMPINATO U. (1999). Selective blockade of serotonin2C/2B receptors enhances mesolimbic and mesostriatal dopaminergic function: a combined in vivo electrophysilogical and microdialysis study. NEUROSCIENCE. vol. 91, pp. 587-597.       

DI GIOVANNI G., DI MASCIO M., DI MATTEO V., ESPOSITO E. (1998). The effect of acute and chronic treatment with amisulpride on the spontaneous activity of midbrain dopamine neurons. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. vol. 287, pp. 51-57.       

DI MATTEO V., DI GIOVANNI G., DI MASCIO M., ESPOSITO E. (1998). Role of the serotoninergic system in the control of mesocorticolimbic dopaminergic function. CNS DRUG REVIEWS. vol. 4, pp. 107-116.       

DI MATTEO V., DI GIOVANNI G., DI MASCIO M., ESPOSITO E. (1998). Selective blockade of serotonin2C/2B receptors enhances dopamine release in the rat nucleus accumbens. NEUROPHARMACOLOGY. vol. 37, pp. 265-273.       

DI MASCIO M., DI GIOVANNI G., DI MATTEO V., PRISCO S., ESPOSITO E. (1998). Selective serotonin reuptake inhibitors reduce the spontaneous activity of dopaminergic neurons in the ventral tegmental area. BRAIN RESEARCH BULLETIN. vol. 46, pp. 547-554.       

POSTORINO A., SERIO R., MULE' F., ADAMO E. B., DI GIOVANNI G., MARINI R. (1993). Modulation of non-adrenergic non-cholinergic inhibitory transmission in rat duodenum: role of opiates and 5-idroxytryptamine. ARCHIVES ITALIENNES DE BIOLOGIE. vol. 131, pp. 235-243.

Book Chapters

CASARRUBEA, M., MAGNUSSON, M. S., DI GIOVANNI, G., ROY, V., ARABO, A., SANTANGELO, A., CRESCIMANNO, G., (2016). Application of T-Pattern Analysis in the Study of Rodent Behavior: Methodological and Experimental Highlights. Discovering Hidden Temporal Patterns in Behavior and Interaction: T-Pattern Detection and Analysis with THEME™, 217-235.

PIERUCCI M, CHAMBERS S, PARTRIDGE L, DE DEURWAERDÈRE, P., DI GIOVANNI G. (2014) Role of Central Serotonin Receptors in Nicotine Addiction. In: Nicotinic Receptors. Ed. Lester RAJ. The Receptors Volume 26, 2014, pp 279-305. Print ISBN 978-1-4939-1166-0

INVERNIZZI R., ESPOSITO E., DI MATTEO V., DI GIOVANNI G (2013) Microiontophoresis and Related Methods. In: Stolerman I., Price L. (Ed.) Encyclopedia of Psychopharmacology: Springer Reference (www.springerreference.com). Springer-Verlag Berlin Heidelberg, 2013. DOI: 10.1007/SpringerReference_169261 2011-01-31 23:00:00 UTC

GALATI S, DI GIOVANNI G. (2013) Intracerebral Human Microdialysis in Parkinson’s Disease. Eds. Di Giovanni, G; Di Matteo, V. Microdialysis Techniques in Neuroscience, Neuromethods, Vol. 75. Pag 209-223. Springer Protocols. ISBN 978-1-62703-172-1

DI GIOVANNI G, PIERUCCI M, PESSIA M, DI MATTEO V. (2013) In Vivo Microdialysis to Study Striatal Dopaminergic Neurodegeneration. In: Microdialysis Techniques in Neuroscience. Ch 2. Eds. Di Giovanni, G; Di Matteo, V. Neuromethods, Vol. 75. Pag 23-42. Springer Protocols. ISBN 978-1-62703-172-1.

D'ADAMO MC, HANNA MG, DI GIOVANNI G, PESSIA M. (2012) Episodic Ataxia Type 1. in: GeneReviews at GeneTests: Medical Genetics Information Resource [database online]. Copyright, University of Washington, Seattle, 1997-2010. Available at http://www.genetests.org.

ESPOSITO E, DI MATTEO V, PIERUCCI M, BENIGNO A, PESSIA M, PITRUZZELLA A, ZAMMIT C, VALENTINO M, MUSCAT R, DI GIOVANNI G. (2012) Serotonin-Dopamine Interaction in Nicotine Addiction: Focus on 5-HT2C receptors. In: Nicotine Addiction: Prevention, Health Effects and Treatment Options. Ed. G. Di Giovanni. Pag. 25-52. Nova Publishers, New York. ISBN 978-1620812907

DI GIOVANNI G., PIERUCCI M., DI MATTEO V. (2011). Monitoring Dopamine in the mesocorticolimbic and nigrostriatal systems by microdialysis: relevance for mood disorders and Parkinson’s disease. In: Applications of Microdialysis in Pharmaceutical Science. Ed: Tsai T-H. John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118011294.ch4.

DI GIOVANNI G. (2011) Serotonin dysfunction in Parkinson’s Disease. In: Movement Disorders: Causes, Diagnoses and Treatments. Ch1. Eds. Larsen BJ, Nova Publishers, New York. ISBN-13: 978-1612092003

DI GIOVANNI G., ESPOSITO E., DI MATTEO V. (2011). The 5-HT2C receptor subtype controls central dopaminergic systems: evidence from electrophysiological and neurochemical studies. In: 5-HT2C Receptors in the Pathophysiology of CNS Disease. Eds. Di Giovanni G., Esposito E., Di Matteo V. The Receptors, Volume 22, 215-247, Springer, New York.

DI GIOVANNI G., DI MATTEO V, PIERUCCI M, ESPOSITO E. (2009). Preferential Modulation of the Gabaergic vs. Dopaminergic Function in the Substantia Nigra by 5-HT2C Receptor Signaling. In: The Basal Ganglia IX. Advances in Behavioral Biology, Volume 58, Part 3, 285-296, Eds: Groenewegen HJ; Voorn P; Berendse HW; Mulder AB; Cools A. NEW YORK: Springer,

DI MATTEO V, PIERUCCI M, BENIGNO A., ESPOSITO E., CRESCIMANNO G., CASARRUBEA M., DI GIOVANNI G (2009). Nitric Oxide Modulation of the Dopaminergic Nigrostriatal System - Focus on Nicotine Action. In: The Basal Ganglia IX. ADVANCES IN BEHAVIORAL BIOLOGY, vol. 58, p. 309-321, Eds: Groenewegen HJ; Voorn P; Berendse HW; Mulder AB; Cools A. NEW YORK: Springer, ISBN: 978-1-4419-0339-6, ISSN: 0099-6246, doi: 10.1007/978-1-4419-0340-2_2

DI GIOVANNI G., DI MATTEO V, PIERUCCI M, ESPOSITO E. (2008). Serotonin 5-HT 2C Receptor and Dopamine Function in Depression. NEW YORK: Nova Publisher (UNITED STATES). In "Dopamine Research Advances". Ed: Watanabe A.   131-144. ISBN: 1-60021-820-2.

DI MATTEO V, DI GIOVANNI G., PIERUCCI M, ESPOSITO E. (2008). Electrophysiological and Neurochemical in Vivo Studies on Serotonin 5-HT 2C Control of Central Dopaminergic Function.  NEW YORK: Nova Publisher (UNITED STATES). In "Dopamine Research Advances" Ed: Watanabe A.   87-111 ISBN: 1-60021-820-2

DI MATTEO V, ESPOSITO E, PIERUCCI M, BENIGNO A, DI GIOVANNI G. (2008). The Life Cycle of the Dopaminergic Neurons in the Substantia Nigra. ISBN: 1-60021-820-2. NEW YORK: Nova Publisher (UNITED STATES). In "Dopamine Research Advances" Ed: Watanabe A.   51-85. ISBN: 1-60021-820-2

DI MATTEO V., PIERUCCI M., DI GIOVANNI G., ESPOSITO E. (2007). Biochemical and therapeutic effects of antioxidants in the treatment of Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis. In G. Ali Qureshi and S. Hasan Parvez: “Oxidative Stress and Neurological Disorders”. Elsevier pp 611-652. ISBN: 0444528091

DI GIOVANNI G., BENIGNO A., LICCIARDI A., ESPOSITO E. (2007). Antioxidants dietary intake and Parkinson’s disease. In G. DI GIOVANNI. "The Basal Ganglia Pathophysiology: Recent Advances" Research Signpost, India. pp 253-283.

ESPOSITO E, DI MATTEO V, PIERUCCI M, BENIGNO A, DI GIOVANNI G (2007). ROLE OF CENTRAL 5-HT2C RECEPTOR IN THE CONTROLL OF BASAL GANGLIA FUNCTIONS. In: GIUSEPPE DI GIOVANNI. THE BASAL GANGLIA PATHOPHYSIOLOGY: RECENT ADVANCES. p. 97-127, TRIVANDRUM:Transworld Research Network, ISBN: 8178952688

BENIGNO A., ESPOSITO E., CRESCIMANNO G., DI MATTEO V., AND DI GIOVANNI G. (2007). Inflammation in Parkinson’s disease: therapeutic implications In G. DI GIOVANNI. “The Basal Ganglia Pathophysiology: Recent Advances” Research Signpost, India. pp 159-189.

BENIGNO A, LICCIARDI A, DI GIOVANNI G (2007). THE SUBSTANTIA NIGRA DOPAMINERGIC NEURONS. In: A.GERBINO, G. ZUMMO, G. CRESCIMANNO. Experimental Medicine Reviews. vol. 1, p. 117-127, PALERMO:PIUMELIA RICERCA, ISBN: 978-88-89876-08-4

DI MASCIO M, DI GIOVANNI G, E. ESPOSITO (1998). Fourier analysis applied to the study of the electrical activity of midbrain dopaminergic neurons. In: International School of Biopysics: Neural circuit and Network. NATO ASI SERIES. SERIES F, COMPUTER AND SYSTEM SCIENCES, vol. 167, p. 41-51, BERLIN:Springer, ISBN: 978-3540649298, ISSN: 0258-1248

Abstracts of Conference

BARUCHIN L. J., VENZI M., DI GIOVANNI G., VINCENZO CRUNELLI V. Challenging the dogma: ethosuximide reduces natural and pentobarbital-induced spindles and non-REM sleep. Society for Neuroscience 2015 Abstracts. 766.15.

DEIDDA G., COLANGELI, R., DI MAIO, R., PIERUCCI, M., DI GIOVANNI, G., 2015. Lateral habenula in nicotine addiction: an electrophysiological In vivo study in rats. Society for Neuroscience 2015 Abstracts. 140.06

COLANGELI, R., DI MAIO, R., PIERUCCI, M., DI GIOVANNI, G., 2015. Interaction between Cannabinoid type 1 and Serotonin 2C Receptors in the pilocarpine model of status epilepticus in rat. Society for Neuroscience 2015 Abstracts. 497.06.

CASSAR D., PIERUCCI M., COLANGELI R., DI GIOVANNI G. Acute nicotine induces anxiety and disrupts temporal pattern organization of rat exploratory behavior in hole-board: a potential role for the lateral habenula. IX MMSC, 2-3 December 2015.

DELICATA F., PIERUCCI M., DI GIOVANNI G. 5-HT 2C receptor modulation of the lateral habenula activity: an electrophysiological and neuroanatomical study. IX MMSC, 2-3 December 2015.

COLANGELI R., PIERUCCI M., DELICATA F., DI GIOVANNI G. Synergistic activity of cannabinoid type 1 and serotonin 2B/2C receptors for the prevention of status epilepticus in rats. IX MMSC, 2-3 December 2015.

PIERUCCI M., COLANGELI R., DELICATA F., DI GIOVANNI G. Role of the Lateral Habenula in mediating rewarding properties of nicotine. IX MMSC, 2-3 December 2015.

DI GIOVANNI G. Role of 5-HT2C Receptors in Temporal Lobe Epilepsy. WG 3/4 CM1103, Siena 29-30th of May 2014.

DI GIOVANNI G., ERRINGTON A,, CRUNELLI V. P1.1 Modulation of Extrasynapitic GABAA Receptors By G-Protein-Coupled Receptors. CM1103 “Interdisciplinary Chemical Approaches for Neuropathology” in association with the “4th Neuroscience Day @ University of Malta”. Xjenza Online. 1(2):103.

PIERUCCI M., GAMMAZZA AM., DI GIOVANNI G. P2.8 EFFECT OF ACUTE AND REPEATED NICOTINE ADMINISTRATION ON THE ELECTRICAL ACTIVITY OF THE LATERAL HABENULAR NEURONS IN RATS. CM1103 “Interdisciplinary Chemical Approaches for Neuropathology” in association with the “4th Neuroscience Day @ University of Malta”. Xjenza Online. 1(2):108.

DAVID F., SCHMIEDT J., ORBAN G., DI GIOVANNI G., UEBELE V.N., RENGER J.J., LERESCHE N., LAMBERT R.C. AND CRUNELLI V. Sleep slow waves are gated by T-type Ca2+ channels of thalamocortical neurons (2012) In: Society for Neuroscience, 2012. Annual meeting of Neuroscience society. (746.08/D31 on-line). New Orleans: Society for Neuroscience (UNITED STATES).

McCAFFERTY C, DAVID F, VENZI M, DI GIOVANNI G, ORBAN G, UEBELE VN, RENGER JJ, LAMBERT RC, LERESCHE N, CRUNELLI V. (2012) T-type calcium channels of cortical but not thalamocortical neurons are necessary for absence seizures. In: Society for Neuroscience, 2012. Annual meeting of Neuroscience society. (159.04/K14 on-line). New Orleans: Society for Neuroscience (UNITED STATES).

CAVACCINI A, YAGÜE JG, ERRINGTON AC, CRUNELLI V, DI GIOVANNI G (2012) Opposite effects of thalamic 5-HT2A and 5-HT2C receptor activation on tonic GABA-A inhibition: implications for absence epilepsy. In: Society for Neuroscience, 2012. Annual meeting of Neuroscience society. (138.03/B57 on-line). New Orleans: Society for Neuroscience (UNITED STATES).

CONNELLY B, FYSON SJ, ERRINGTON AC, COPE DW, DI GIOVANNI G, CRUNELLI V GABA(B) receptors enhance tonic GABA(A) inhibition. In: Society for Neuroscience, 2012. Annual meeting of Neuroscience society. (138.04/     B58 on-line). New Orleans: Society for Neuroscience (UNITED STATES).

DI GIOVANNI G., DE DEURWAERDÈRE P. (2012) Serotonin implication in neuropsychiatric disorders: A translational approach. 4th Conference of the Mediterranean Neuroscience Society, Symposium n.12. Istanbul, September 30th  – October 3rd 2012.

DI GIOVANNI G. (2012) Role of Serotonin in Epilepsy: Focus on 5-HT2 receptors. 4th Conference of the Mediterranean Neuroscience Society. Istanbul, September 30th  – October 3rd 2012.

PIERUCCI M, MARINO GAMMAZZA A, PITRUZZELLA A, ORBAN G, VALENTINO M, MUSCAT R, BENIGNO A, DI GIOVANNI G. (2012) Effect of Acute and Repeated Nicotine Administration on the Electrical Activity of the Lateral Habenular Neurons in Rats. 4th Conference of the Mediterranean Neuroscience Society. Istanbul, September 30th  – October 3rd 2012.

DI GIOVANNI G. (2012) Role of Serotonin in Epilepsy. VIII Malta Medical School Conference, Msida, Malta, November 29th, 2012.

DAVID F, ORBAN G, DI GIOVANNI G, UEBELE VN, RENGER JJ, CRUNELLI V, LERESCHE N, LAMBERT RC (2010) Parodoxical enhancement of sleep delta oscillations by partial block of T-type Ca2+ channels: a combined in vivo and computational study. In: Society for Neuroscience, 2010. Annual meeting of Neuroscience society. (on-line). San Diego: Society for Neuroscience (UNITED STATES).

ORBAN G, DAVID F, DI GIOVANNI G, COPE DW, BOWLES K, UEBELE VN, RENGER JJ, LAMBERT RC, LERESCHE N, CRUNELLI V. (2010) Block of T-type calcium channels of thalamocortical neurones by TTA-P2 does not suppress absence seizures. In: Society for Neuroscience, 2010. Annual meeting of Neuroscience society. (on-line). San Diego: Society for Neuroscience (UNITED STATES).

DI GIOVANNI G, ORBAN G, FYSON S J, CRUNELLI V, COPE D W (2009). Thalamic extrasynaptic GABAA receptor gain-of-function is necessary and sufficient for absence epilepsy. In: Society for Neuroscience, 2009. Annual meeting of Neuroscience society. (513.1/B90 pp. on-line). Chicago: Society for Neuroscience (UNITED STATES).

DI GIOVANNI, G, ORBAN, G, FYSON, SJ, CRUNELLI, V, COPE, DW (2009). Thalamic extrasynaptic GABAA receptors are required for typical absence seizures. Physiological Society Symposium, Cardiff, December 2009, PC39.

DI GIOVANNI G., COPE D.W, CRUNELLI V. (2008). Cholinergic and monoaminergic modulation of tonic GABAA inhibition in the rat dorsal lateral geniculate nucleus. In: Society for Neuroscience, 2008. Annual meeting of Neuroscience society. (531.2/D3 pp. on-line). WASHINGTON: Society for Neuroscience (UNITED STATES).

DI GIOVANNI G., COPE D.W, ERRINGTON A.C, FYSON S.J, CRUNELLI V. (2007). Extrasynaptic GABAA receptor gain-of-function in absence epilepsy: genetic absence epilepsy rats from Strasbourg. In: Society for Neuroscience. Annual meeting of Neuroscience society. San Diego, ( 142.9/I5, pp. on-line).

ERRINGTON A.C, COPE D.W, FYSON S.J, DI GIOVANNI G., CRUNELLI V. (2007). Extrasynaptic GABAA receptor gain-of-function in absence epilepsy: monogenic mutant mice. In: Society for Neuroscience. Annual meeting of Neuroscience society. (142.8/I4, pp. on-line).

FYSONS S.J, COPE D.W, ERRINGTON A.C, DI GIOVANNI G., LERESCHE N, CRUNELLI V. (2007). Extrasynaptic GABAA receptor gain-of-function in absence epilepsy: GHB and THIP pharmacological models. In: Society for Neuroscience. Annual meeting of Neuroscience society. ( 142.7/I3, pp. on-line).

DI GIOVANNI G., DI MATTEO V, PIERUCCI M, BENIGNO A, CRESCIMANNO G, CASARRUBEA M, ESPOSITO E. (2007). Role of nitric oxide on the conrol of the dopaminergic Nigrostriatal system: a combined electrophysiological And dialysis analysis in rats. IBAGS IX. EGMOND AAN ZEE. 2nd – 6th September. ( P-090, pp. 112). : (NETHERLANDS).

DI GIOVANNI G., DI MATTEO V, PIERUCCI M, INVERNIZZI RW, ESPOSITO E. (2007). Preferential modulation of the gabaergic vs. dopaminergic function in the substantia nigra by 5-TH2C receptor signaling: electrophysiological and neurochemical evidence. IBAGS IX. Egmond aan Zee. 2nd – 6th September. ( P-091, pp. 112). (NETHERLANDS).

DI MATTEO V, PIERUCCI M, BENIGNO A, CRESCIMANNO G, ESPOSITO E, DI GIOVANNI G. (2007). The Pivotal Role of Nitric Oxide in 6-OHDA-induced Dopaminergic Neurotoxicity: Neurochemical Evidences in Rats. Movement Disorders. (22:12, pp. VII). ISBN/ISSN: 0885-3185. : Wiley-Liss (UNITED STATES). 7 October 2007 Washington, D.C., USA.Twenty First Annual Symposium on Etiology, Pathogenesis, and Treatment of Parkinson’s Disease.

BENIGNO A, DI MATTEO V, PIERUCCI M, CRESCIMANNO G, ESPOSITO E, LICCIARDI A, DI GIOVANNI G. (2007). Involvement of nitric oxide in the nigrostriatal dopaminergic system degeneration: a study on the 6-OHDA model of Parkinson's disease. 58° Congresso della Società Italiana di Fisiologia. Lecce. 19-20-21 Settembre. (pp. P11).

CASARRUBEA M, SORBERA F, MATINELLA A, DI GIOVANNI G., BENIGNO A, CRESCIMANNO G. (2007). Modifications induced on rat exploratory behavior by acoustic stimulation: a multivariate analysis. Congresso SINS 2007. Verona. 2-30/09/2007. (pp. SAT-66).

DI GIOVANNI G., PIERUCCI M, DI MATTEO V, CRESCIMANNO G, BENIGNO A, ESPOSITO E. (2006). CRUCIAL ROLE OF THE 5-HT2C RECEPTOR IN REGULATING THE ACTIVITY OF THE SUBSTANTIA NIGRA PARS RETICULATA NEURONS: AN ELECTROPHYSIOLOGICAL STUDY IN RATS. In: FENS Forum Abstracts. FENS 2006. VIENNA. 07-12 JULY. (vol. vol.3, pp. A075.6).

DI GIOVANNI G., PIERUCCI M., DI MATTEO V., CRESCIMANNO G., BENIGNO A., ESPOSITO E. (2006) Activation Of 5-Ht2c Receptors Stimulates Gaba-Ergic Neurons Of The Rat Substantia Nigra Pars Reticulata: An In Vivo Microintophoretic Study. Congresso della Società Italiana di Fisiologia, Ravenna.

DI GIOVANNI G, PIERUCCI M, DI MATTEO V, GIULIANO DA, ESPOSITO E, BENIGNO A. (2006) Unilateral Nigral Lesion Induces Dramatic Bilateral Modification In Rat Brain Monoamine Levels: A Neurochemical Study. Congresso della Società Italiana di Fisiologia, Ravenna.

DI GIOVANNI G., DI MATTEO V., PIERUCCI M., BENIGNO A., ESPOSITO E. (2006) Crucial Role of the 5-HT2C Receptor in Regulating the Activity of the Substantia Nigra Pars Reticulata Neurons: An Electrophysiological Study in Rats. 5th Forum of European Neuroscience - Vienna 2006. FENS Abstr., vol.3, A075.6, 2006

DI GIOVANNI G., AMATO G., PIERUCCI M., ESPOSITO E., DI MATTEO V., BENIGNO A. (2005). Muscarinic Modulation Of The Activity Of The Substantia Nigra Pars Compacta Neurons In Rats: Role Of The Tegmental Pedunculopontine Nucleus. Congresso della Società Italiana di Fisiologia. 27-30 Settembre, Palermo.       

DI GIOVANNI G., BENIGNO A., CRESCIMANNO G., AMATO G., POGGI A., PIERUCCI M., ESPOSITO E., DI MATTEO V. (2005). A Rapid And Quantitative Technique To Study Striatal Dopaminergic Neurodegeneration By In Vivo Reverse Microdialysis In Rats. Congresso della Società Italiana di Fisiologia. 27-30 Settembre, Palermo.       

DI MATTEO V., POGGI A., PIERUCCI M., DI GIOVANNI G., BENIGNO A., ESPOSITO E. (2005). Acetylsalycilic Acid (Asa) Protects Against Neuronal Damage Induced By 1-Methyl-4-Phenylpyridinium Iodide (Mpp+) In Rat Striatum: An In Vivo Microdialysis Study. Molecular Mechanisms of Neurodegeneration", Milan Italy, May. MAGGIO 2005. (vol. P 22).       

DI GIOVANNI G., FERRARO G., SARDO P., DI MAIO R., CARLETTI F., LA GRUTTA V. (2004). Microiontophoretic Evidence that Nitric Oxide Alters Spontaneous Activity of the Substantia Nigra Pars Reticulata Neurons in the Rat. Congresso della Società Italiana di Fisiologia. Pisa, Ottobre.       

ESPOSITO E., DI MATTEO V., PIERUCCI M., DI GIULIO C., CACCHIO M., DI GIOVANNI G., BENIGNO A., AMATO G. (2004). Selective stimulation of serotonin2c receptors blocks the enhancement of striatal accumbal dopamine release by nicotine administration. Society for Neuroscience. Washington, DC Ottobre. (vol. No. 953.16.). Online.       

FERRARO G., DI GIOVANNI G., DI MAIO R., CARLETTI F., SARDO P. (2004). Role of nitric oxide in the controlo of maximal dentate gyrus activation by Lamotrigine in the rat.

SARDO P., DI GIOVANNI G., R. DI MAIO, CARLETTI F., FERRARO G. (2004). Nitric Oxide Influences The Activity Of Neurones In The Subthalamic Nucleus Of The Rat. Congresso della Società Italiana di Fisiologia. PISA, OTTOBRE.       

FERRARO G. SARDO P., DI GIOVANNI G., DI MAIO R., LA GRUTTA V. (2003). Involvement of Nitric Oxide in Maximal Dentate Gyrus Activation, in the Rat. (vol. 102, pp. 118). S.I.F., Chieti.       

FERRARO G., SARDO P., DI GIOVANNI G., GALATI S., LA GRUTTA V. (2003). NGF/Nitric oxide relationships in the cortico-subcortical motor circuit. Pflugers Arch – Eur. J. Physiol. (vol. 445: R58,, pp. 158). S.I.F., Ferrara 2002.       

SARDO P., FERRARO G., DI GIOVANNI G., GALATI S., LA GRUTTA V. (2003). Nitric oxide influence on the activity of striatal and pallidal neurones in the rat. Pflugers Arch – Eur. J. Physiol. (vol. 445: R62, pp. 172). ISBN/ISSN: 0031-6768. S.I.F., Ferrara 2002.       

DI GIOVANNI G., DI MATTEO V., LA GRUTTA V., ESPOSITO E. (2002). Serotonin, excites non-dopaminergic neurons in the rat Substantia Nigra and Ventral Tegmental Area by activitang 5-HT2C receptors. Pflugers Arch – Eur. J. Physiol. (vol. 444: R25, pp. 52). ISBN/ISSN: 0031-6768. S.I.F., Ancona 2001.       

G. FERRARO, P. SARDO, DI GIOVANNI G., S. GALATI, LA GRUTTA V. (2002). Action of compounds manipulating the nitric oxide system in the rat neostriatum: microiontophoretic studies. Pflugers Arch - Eur. J. Physiol. (vol. 444: R26, pp. 54). ISBN/ISSN: 0031-6768. S.I.F., Ancona 2001.       

CECI, A, BASCHIROTTO, DI GIOVANNI G., GRAUERT M. (1999). Effects of antipsychotics on firing rate of medial prefrontal-cortical neurons. An extracellular in vivo study. Society of Neuroscience. (vol. 25 Abstr. 733.2, pp. 1832). Annual Meeting of Society for Neuroscience.       

DI GIOVANNI G., DI MATTEO V., DI MASCIO M., GAMBI D., ESPOSITO E. (1999). Preferential modulation of mesolimbic versus nigostriatal dopaminergic function by serotonin2C receptors. A combined in vivo electrophisyological and microdialysis study. S 20 n. 12 1999. Neuroscience Letters. (vol. Suppl. 52 S 20, pp. Abstr. 12). Annual Meeting of Italian Society for Neuroscience.       

ESPOSITO E., DI MASCIO M., DI MATTEO V., DI GIOVANNI G. (1999). Serotonin2C receptor agonists inhibit dopaminergic neurons in the ventral tegmental area by activating GABA-ergic interneurons. Soc. Neurosci. (vol. 25 Abstr. 589.16, pp. 1471). Annual Meeting of Society for Neuroscience.       

DI GIOVANNI G., DE DEURWAERDERE P., DI MASCIO M., DI MATTEO V., ESPOSITO E., SPAMPINATO U. (1998). Selective blockade of serotonin2C/2B receptors enhances mesolimbic and mesostriatal dopaminergic function: a combined in vivo. electrophysilogical and microdialysis study. Soc. Neurosci. Vol 24, 355, ()1998. International Meeting of Society for Neuroscience. (vol. 24 Abstr. 141.7, pp. 355).       

DI GIOVANNI G., DI MASCIO M., DI MATTEO V., ESPOSITO E. (1998). The effect of acute and chronic treatment with Amisulpride on the spontaneous activity of midbrain dopamine neurons. American College of Neuropsychopharmacology. (pag 339). Annual Meeting of American College of Neuropsychopharmacology. 14-18 dicembre 1998. (vol. Abstr 159, pp. 339). Las Croabas (Porto Rico).       

DI GIOVANNI G., DI MATTEO V., M. DI MASCIO, GAMBI F., ESPOSITO E. (1998). Il recettore 5-HT2C controlla selettivamente la funzione dopaminergica mesolimbica. 8° (pag 205). Napoli, 29 settembre-3 ottobre 1998. 8° Congresso Societa' Italiana di Psichiatria Biologica. 29 settembre-3 ottobre. (vol. Abstr. P.2, pp. 205). Napoli.       

DI MASCIO M., DI GIOVANNI G., DI MATTEO V., ESPOSITO E. (1998). Applicazione multimediale per simulare un esperimento di elettrofisiologia sul sistema nervoso di ratto. Tecnologie Informatiche e Telematiche Applicate alle Neuroscienze. Milano 1998.       

DI MASCIO M., DI GIOVANNI G., DI MATTEO V., ESPOSITO E. (1998). Decreased chaos of midbrain dopaminergic neurons after serotonin denervation. Soc. Neurosci. Vol 24, 355, (Abstr. 141.4)1998. International Meeting of Society for Neuroscience. (vol. 24 Abstr. 141.4, pp. 355).       

DI MASCIO M., DI GIOVANNI G., PRISCO S., DI MATTEO V., ESPOSITO E. (1998). Selective serotonin reuptake inhibitors reduce the spontaneous activity of dopaminergic neurons in the ventral tegmental area. Novel Theraupetic Strategies in the Schizophrenic Spectrum and Bipolar Disorders. (vol. Abstr. 33, pp. 164-165). Venezia, 13-14 Marzo 1998.       

DI GIOVANNI G., DI MATTEO V., DI MASCIO M., ESPOSITO E. (1997). Selective blockade of serotonin2C/2B receptors enhances mesolimbic and mesostriatal dopaminergic function. Trends in Neurosciences. (vol. Suppl. 9, pp. Abstr. 121). Italian Society for Neuroscience.       

DI MASCIO M., DI GIOVANNI G., ESPOSITO E. (1997). Fourier analysis applied to the study of the electrical activity of midbrain dopaminergic neurons. Joint Israeli-Italian Workshop on Trasduction Mechanisms and Synaptic Function. Erice, Italy. June 23-26.       

ESPOSITO E., DI GIOVANNI G., DI MASCIO M. (1997). The effect of serotoninergic agents on the activity of midbrain dopaminergic neurons is a function of the density-power-spectrum of their interspike intervals. Annual Meeting Society for Neuroscience. (vol. 23, pp. 1210). Abstr. 481.4.

Prof M Valentino

Hb Setif [alpha 94(G1)Asp-->Tyr] in Malta. Borg I, Valentino M, Fiorini A, Felice AE.  Hemoglobin, 1997, 21(1): 91-96.

Emerging insights into the genesis of Cerebral ischemia and Stroke – review article. Valentino M and Graf R.  Scienza, 4 (1), 1999. 

Malignant edema formation following transient MCA occlusion: decrease of cerebral perfusion pressure causes secondary elevation of glutamate.  Toyota S, Valentino M, Graf R, W.-D. Heiss. J. Cereb. Blood Flow Metab. 2001.     

Extracellular glutamate accumulates only in final, ischemic stage of progressive epidural mass lesion in cats.  Toyota S, Valentino M, Graf R, W.-D. Heiss. J. Cereb Blood Flow Metab. Suppl. 2001.

Elevation of extracellular glutamate in the final, ischemic stage of progressive epidural mass lesion in cats.Toyota S, Graf R, Dohmen C, Valentino M, Grond M, Wienhard K, Heiss W.-D.  J.Neurotrauma,18(12): 1349-57, 2001.

Malignant infarction in cats after prolonged middle cerebral artery occlusion: glutamate elevation related to decrease of cerebral perfusion pressure. Toyota S,Valentino M, Graf R, Yoshimine T, Heiss W.-D.  Stroke; 33(5): 1383-91.2001.

Ischemic depression of neuronal activity: real time comparison between DC potential changes and alterations of ion and transmitter homeostasis.  Brain activation and CBF control., Tomida, M. Kanno I and Hamel E,Editors. ISBN: 0444508740.2002.

Identification of malignant brain edema after hemispheric stroke by PET-imaging and microdialysis. Heiss W.-D, Dohmen C, Sobesky J, Kracht L, Bosche B, Staub F, Toyota S, Valentino M, Graf R.  Acta Neurochir, 86: 237-40.2003.

Prediction of malignant infarction: perifocal neurochemical monitoring following prolonged MCA occlusion in cats. Toyota S,Valentino M, Graf R, Yoshimine T, Heiss W.-D.  Acta Neurochir, 86: 153-7,2003.

Identification of malignant brain edema after hemispheric stroke by PET-imaging and microdialysis. Heiss W.-D, Dohmen C, Sobesky J, Kracht L, Bosche B, Staub F, Toyota S, Valentino M, Graf R. Acta Neurochirurgica,Springer-Verlag, 237-240, ISBN-10: 3211009191,2003.

Identification of oligodendrocytes in experimental disease models.  Invited review. J.K.Ness, M.Valentino, S. McIver and M.P. Goldberg. Glia. 50(4):321-8.2005.

Two-photon microscopy- sequential imaging studies in vivo. Mario Valentino, C. Zammit, G. Di Giovanni, R. Muscat.  Malta Medical Journal, 23,(3),2011.

Vulnerability of white matter to ischemia varies during development Christian Zammit, Mario Valentino and Richard Muscat. Malta Medical Journal, 23, (3),2011.

Lateral Habenular Contribution in Nicotine Addiction: Focous on Dopamine, GABA and Serotonin Interactions. Pierucci M, Pitruzzella A, Valentino M, Muscat R, Di Giovanni G. Malta Medical Journal, 23, (3),2011.

Nitric Oxide Modulation Of The Basal Ganglia Circuitry: Therapeutic Implication For Parkinson's Disease And Other Motor Disorders.  M. Pierucci, S.Galati, M. Valentino, V. Di Matteo, A. Benigno, A. Pitruzzella, R. Muscat and G. Di Giovanni. CNS & Neurological Disorders. Drug Targets, 10 (7):777-791, 2011.

Shedding Light on Brain Injury. Mario Valentino. ISBN: 978-99957-0-162-8. 2011.

Serotonin-Dopamine interaction in Nicotine Addiction: Focus on 5-HT2C Receptors. E. Esposito, V. Di Matteo, M. Pierucci, A. Benigno, M. Pessia, A. Pitruzzella, C. Zammit, M. Valentino, R. Muscat, G. Di Giovanni. Nicotine Addiction: Prevention, Health Effects and Treatment Options, Nova Publisher, New York, ISBN:978-1-62081, 25-52. 2012.

Exploring the dynamic brain in vivo. M.Valentino, C.Zammit, G.Gravino, B.Galea,  G.Di Giovanni and R.Muscat. Submitted to Scienza for review, 2012.

Dysfunction of voltage-gated K+ Channels Kv1.1 in sciatic nerve causes spontaneous and stress-induced neuromuscular hyperexcitability Brunetti O, Imbrici P, Botti FM, Pettorossi VE, D’Adamo MC,Valentino M, Zammit C Mora M, Di Giovanni G, Muscat R and Pessia M..  Neurobiology of Disease, 47, 310-321, 2012.

Central axons preparing for myelination are highly sensitivity to ischemic injury due to the transient expression of Ca2+ channels. A. James, C. Zammit, M. Valentino, S. Back and R.Fern.  Ann Neurology.72:936–951.2012.

Unraveling white matter neurometabolism: proof of astro-axonal shuttling and its regulation by the B2-adrenergic tone. Laureys G, Valentino M, Demol F, Michotte Y, Kooijman R, Dekeyser J, Clinckers R. (Submitted to Nature Neuroscience).

The spectrum of ischemia-induced white matter injury varies with age. C.Zammit, R.Muscat and M. Valentino. Submitted to Scienza, 2013.

Prof R Balzan

Azzopardi, M., Farrugia, G., Balzan, R. (2017) Cell-cycle involvement in autophagy and apoptosis in yeast. Mech. Ageing Dev. 161, 211–224.

Farrugia, G., & Balzan, R. 2013, "The Propoptotic Effect of Traditional and Novel Nonsteroidal Anti-Inflammatory Drugs in Mammalian and Yeast Cells.", Oxidative Medicine and Cellular Longevity, vol. 2013 Article ID 504230, pp. 1-17 doi: 10.1155/2013/504230.

Farrugia, G., Bannister, W., Vassallo, N. & Balzan, R. 2013. "Asprin-induced apoptosis of yeast cells is associated with mitochondrial superoxide radical accumulation and NAD(P)H oxidation.", FEMS Yeast Res 13, 755-768 doi: 10.1111/1567-1364.12075 [Epub ahead of print]

Farrugia, G. & Balzan, R. 2012, "Oxidative stress and programmed cell death in yeast.", Front. Oncol. 2:64. doi: 10.3389/fonc.2012.00064, , pp. 1-21.

Sapienza, K. and Balzan, R. 2008, " Aspirin and Apoptosis " in Aspirin and Health Research Progress , ed. P.I. Quinn, Nova Science Publishers, New York, pp. 77-110.

Sapienza, K., Bannister, W. & Balzan, R. 2008, "Mitochondrial involvement in aspirin-induced apoptosis in yeast", Microbiology, vol. 154, pp. 2740-2747.

Shaw, G.C., Cope, J.J., Li, L., Corson, K., Hersey, C., Ackermann, G.E., Gwynn, B., Lambert, A.J., Wingert, R.A., Traver, D., Trede, N.S., Barut, B.A., Zhou, Y., Minet, E., Donovan, A., Brownlie, A., Balzan, R., Weiss, M.J., Peters, L.L., Kaplan, J., Zon, L.I. & Paw, B.H. 2006, "Mitoferrin is essential for erythroid iron assimilation", Nature, vol. 440, no. 7080, pp. 96-100.

Sapienza, K. & Balzan, R. 2005, "Metabolic aspects of aspirin-induced apoptosis in yeast", FEMS Yeast Res, vol. 5, no. 12, pp. 1207-1213.

Balzan, R., Sapienza, K., Galea, D.R., Vassallo, N., Frey, H. & Bannister, W.H. 2004, "Aspirin commits yeast cells to apoptosis depending on carbon source", Microbiology, vol. 150, pp. 109-115.

Vassallo, N., Galea, D.R., Bannister, W.H. & Balzan, R. 2000, "Stimulation of yeast 3-phosphoglycerate kinase gene promoter by paraquat", Biochem Biophys Res Commun, vol. 270, no. 3, pp. 1036-1040.

Balzan, R., Agius, D.R. & Bannister, W.H. 1999, "Cloned prokaryotic iron superoxide dismutase protects yeast cells against oxidative stress depending on mitochondrial location", Biochem Biophys Res Commun, vol. 256, no. 1, pp. 63-67.

Agius, D.R., Bannister, W.H. & Balzan, R. 1998, "Prokaryotic iron superoxide dismutase replaces cytosolic copper, zinc superoxide dismutase in protecting yeast cells against oxidative stress", Biochem Mol Biol Int, vol. 44, no. 1, pp. 41-49.

Balzan, R., Bannister, W.H., Hunter, G.J. & Bannister, J.V. 1995, "Escherichia coli iron superoxide dismutase targeted to the mitochondria of yeast cells protects the cells against oxidative stress", Proc Natl Acad Sci U S A, vol. 92, no. 10, pp. 4219-4223.

Dr R Blundell

Peer Reviewed

Galea, S, Blundell R., (2011) Clinical correlates involving deficiency of Vit D and Calcium. International Journal of Molecular Medicine and Advanced Sciences. 7(3) 12-15.

Galea, S, Blundell R., (2011) Parathyroid hormone and calcitonin regulating calcium levels. Research Journal of Biological Sciences. 6(4): 183-186.

Galea, S, Blundell R., (2011) Physiology of Vitamin D. International Journal of Molecular Medicine and Advanced Sciences. 7(1): 1-4.

Gamudi, D, Blundell, R., (2010) Inherited Cancer Syndrome. International Journal of Molecular Medicine and Advance Sciences. 6(3): 38-42.

Gamudi, D, Blundell, R., (2010) Genetic Screening of Heredity Diseases. Journal of Molecular Genetics 2(2): 20-23.

Gamudi, D, Blundell, R., (2010) Tumor Suppresser Genes. Research Journal of Medical Sciences 4(4): 280-284.

Camilleri, G., Blundell, R., (2009) Pre-Invasive cervical disease and cervical carcinoma. Research Journal of Medical Sciences 3(1): 4-11.

Camilleri, G., Blundell, R., (2009) The Human Papilloma viruses (HPVs) and HPV DNA Testing. Research Journal of Biological Sciences 4(1): 29-36.

Camilleri, G., Blundell, R., (2008) The Mechanisms of HPV-Induced carcinogenesis and the HPV Vaccine. International Journal of Molecular Medicine and Advance Sciences 4(3): 55-61.

Vassallo, J., Blundell, R., (2008) Neurological Diseases and Stem Cell Transplantation – Review Paper. International Journal of Molecular Medicine and Advance Science 4(3): 62-73

Gamudi, N., Blundell, R. (2008) The Link between Stem Cells and Neoplasia. Research Journal of Medical Sciences 3(4): 413-417.

Agius, C.M., Blundell, R. (2008) The Cutting Edge in Stem Cell Medical Applications.  Research Journal of Medical Sciences 2(1): 47-50.

Xuereb, J., Blundell, R. (2008) Chronic Leukaemia. Research Journal of Medical Sciences 2(1): 28-32.

Agius, C.M., Blundell, R. (2008) Medical Applications of stem cell technology in diseases of blood and the circulatory system. Research Journal of Biological Sciences  3(3): 337-341.

Gamudi, N., Blundell, R. (2008) Atielogy and Pathophysiology of Neoplastic Growth. Research Journal of Biological Sciences 2 (2): 77-84.

Xuereb, J., Blundell, R. (2008) The role of cell cycle regulation in cancer. Research journal of Biological Sciences 3(2): 251-257.

Gamudi, N., Blundell, R. (2007) Stem Cells in Perspective. International Journal of Molecular Medicine and Advance Sciences 3(4): 160-165.

Agius, C.M., Blundell, R. (2007) What are Stem Cells? – Review paper. International Journal of Molecular Medicine and Advance Sciences 3(4): 145-150.

Xuereb, J., Blundell, R. (2007) Acute Leukaemia. International Journal of Molecular Medicine and Advance Sciences 3 (4): 138-144.

Blundell, R., Harrison, D.J. (2007) Effect of changes in the Extracellular Matrix (ECM) composition on Clara cell proliferation and death through p21 regulation.  Research Journal of Medical Sciences 1(2): 62-69,

Blundell, R., Harrison, D.J. (2007) Effect of changes in the Extracellular Matrix (ECM) composition on Clara cell differentiation through p21 regulation.  Research Journal of Biological Sciences 2(2): 183-187.

Blundell, R., Harrison, D.J. (2007) Effect of ECM on Clara cell’s expression of p21, p27 and p53.  Research Journal of Applied Sciences 2(3): 327-334.

Blundell, R. (2007) Causes of Infertility. International Journal of Molecular Medicine and Advance Sciences 3(1): 63-65.

Farrugia, A, Blundell R. (2007) In Vitro Fertilisation and other artificial reproductive technology methods. International Journal of Molecular Medicine and Advance Sciences 3(1): 16-23.

Blundell, R. (2007) Genome organization. Research Journal of Medical Sciences 1(1): 6-8.

Blundell, R. (2006) Transgenic Animals. Journal of Animal and Veterinary Advances 5(11): 935-938.

Blundell, R. (2006) The Biology of Small Airway Epithelium. International Journal of Molecular Medicine and Advance Science 2(4): 354-359.

Blundell, R. (2006) DNA fingerprinting. Research Journal of Applied Sciences 1(1-4): 136-140.

Blundell, R. (2006) Epithelial cells interactions. International Journal of Molecular Medicine and Advance Science 2(3): 299-306.

Blundell, R. (2006) What is Genomics?  Research Journal of Biological Sciences 1 (1-4): 40-42

Blundell, R. (2006) The biology of p21.  American Journal of Biochemistry and Biotechnology 2(1): 33-40.

Blundell, R. (2006) The biology of Clara Cells. International Journal of Molecular Medicine and Advance Science 2(3): 307-311.

Blundell, R., Harrison, D.J. (2006) Changes in the expression of p21, p27 and p53 following beta-1 integrin blocking in murine Clara cells cultures. International Journal of Molecular Medicine and Advance Science 2(3): 245-250.

Blundell, R., Felice, A.E., (2006) Detection of new genomic landmarks in the Maltese goat using RAPD PCR. Journal of Animal and Veterinary Advances 5(7); 602-607.

Blundell, R., Harrison, D.J. (2006) Increase in apoptosis by beta-1 integrin blocking through p21 –dependent and –independent mechanisms. International Journal of Molecular Medicine and Advance Science 2(3): 312-318

Blundell, R., Harrison, D.J. (2005) Integrin characterisation in pulmonary bronchioles.  Experimental and Molecular Pathology 79(1): 74-78.

Blundell, R., Kaminski, N., Harrison, D. (2004) Increase in the p21 expression independent of the p53 pathway in bleomycin-induced lung fibrosis. Experimental and Molecular Pathology 77(3): 231-7.

Blundell, R., Harrison, D.J., O’Dea,S (2004) p21Waf1/Cip1 regulates proliferation and apoptosis in airway epithelial cells and alternative forms have altered binding activities.  Experimental Lung Research.  30(6): 447-464.

Blundell, R., Harrison, D.J., Wallace, W.A.H., (2004) Emphysema: the challenge of the remodelled lung.  Journal of Pathology 202: 141-144

McBride, S., Tatrai, E., Blundell, R., Kovacikova, Z., Cardozo, L., Adamis, Z., Smith, T., Harrison, D.J., (2000) Characterisation of lectin binding patterns of mouse bronchiolar and rat alveolar epithelial cells in culture.  The Histochemical Journal, 32: 33-40.

Blundell, R.; (1995) Reintroduction of the local breeds of sheep and goats in Malta.  Cahiers Options Méditerranéennes. Volume 11 - Strategies for Sheep and Goat Breeding.  Pages 97 - 100.

Published Proceedings

Blundell, R., O’Dea, S., Harrison, D.J. (2001) Regulation of p21 induction and cellular localisation in primary lung epithelial cells by extracellular matrix proteins. Journal of Pathology, 193: 14A.

McBride, S., Tatrai, E., Blundell, R., Harrison, D.J. (2000) Characterisation of lectin binding patterns of mouse bronchiolar and rat alveolar epithelial cells in culture.  Journal of Pathology, 190: 47A.

Blundell, R.; Felice, A.E.; (1996) Animals for Bioreactors.  Proceedings of the Biotechnology Symposium, held at the University of Malta

Blundell, R.; (1995) Biotechnology in Curriculum Development.  Proceedings the FAO Regional Seminar, November 6-10, 1995, Malta.

Blundell, R.; (1995) Goats in Malta. Proceedings International Goat Production Course, February 6-17,1995. Zaragoza, Spain, Volume 1; 1 - 6.

Poster/Oral Presentations

O’Dea, S., Blundell, R., Harrison, D.J. (2003) Loss of p21Waf1/Cip1/Sdi1 increases proliferation and apoptotic rates in bronchiolar epithelial cells.  99th International Conference - American Thoracic Society, Seattle, Washington, USA (poster)

O’Dea, S., Blundell, R., Harrison, D.J. (2001) Effect of extracellular matrix proteins on p21 induction and cellular localisation in lung epithelial cells. American Thoracic Society Meeting (poster)

Felice, A.E., Alashtar, A., Vella, J., Al-Shinawi,C., Bezzina Wettinger, S., Blundell, R., Scerri, C., Grech, G. (2001) Human GM1-Ganlgiosidosis: identification of Three Mutations in the Maltese Populations. 10th International Congress of Human Genetics, Austria.

Blundell, R., McBride, S., Harrison, D.J. (2000) Regulation of p21 induction and cellular localisation in primary lung epithelial cells by extra cellular matrix proteins. British Society of Pathology meeting (poster)

Blundell, R., (1999) Genetic regulation of injury responses in lung epithelial cells. Department of Pathology, University of Edinburgh (oral)

McBride, S., Blundell, R., Cardozo, L., Smith,T., Harrison,D.J. (1999) Characterisation of lectins binding patterns of mouse bronchiolar epithelial cells in culture.  British Society of Pathology meeting. (poster)

Al-Ashtar, A., Al-Shinawi, C., Bezzina Wettinger, S., Blundell, R., Scerri, C., Grech, G., Vella, J., Felice, A.E., (1999) Human GM1-gangliosidosis identification of two mutations in IVS 7 in two Maltese families. IV Maltese Medical School Conference (oral)

Blundell, R.; Felice, A.E.; (1996) Animals for Bioreactors.  Biotechnology Symposium, University of Malta (oral)

Blundell, R.; (1995) Biotechnology in Curriculum Development.  Proceedings the FAO Regional Seminar, Malta. (oral)

Reports

Blundell, R. (2001) ‘Cloning Free’ DNA Sequencing Protocols. Submitted at the request of Prof. A. Felice, Department of Physiology and Biochemistry, University of Malta, Malta.

Blundell, R., Harrison, D.J. (1999) Genetics of emphysema - identifying high-risk individuals. Department of Pathology, University of Edinburgh (review paper)

Blundell, R. (1995) Statistics about Sheep and Goats in Malta. Department of Agriculture.

Blundell, R., Felice, A.E. (1995) Testing and treatment of Brucella using Molecular Genetics Techniques. Malta Council for Science and Technology.  Working Group: Agricultural Biotechnology.

Blundell, R.; Felice, A.E.; (1994) The use of genetically recombinant bovine growth Hormone (rbGH).  Malta Council for Science and Technology.  Working Group: Agricultural Biotechnology.

Newspapers

Eczema Spongiotic Dermatatis.  Kullhadd Newspaper.  2nd October, 2011. Page 32.

Dbabar bojod fuq il-gisem.  Kullhadd Newspaper.  11th September, 2011.  Page 22.

Nervi tal-period.  Kullhadd Newspaper.  28th August, 2011. Page 18.

Attakki ta’ paniku.  Kullhadd Newspaper. 24th July, 2011.  Page 22.

Saqajn hoxnin u c-cellulite. Kullhadd Newspaper. 10th July, 2011. Page 22.

Erezzjoni mhux b’sahhitha.  Kullhadd Newspaper. 20th March, 2011. Page 22.

Fellul mal-gisem kollu.  Kullhadd Newspaper. 27th February, 2011. Page 22.

Addressing market cartels.  Malta Independent. Sunday 20th February, 2011. Page 6-7.

Ugieh f’idejn.  Kullhadd Newspaper. 13th February, 2011. Page 24.

Sperm count baxx fl-irgiel.  Kullhadd Newspaper. 9th January, 2011. Page 22.

Ugiegh fis-saqajn.  Kullhadd Newspaper. 19th December, 2010. Page 30.

Fruit Juice Directive ‘useless’ without proper labelling. Malta Independent. 7th December, 2010.

Healthier sugar replacements banned in Malta.  Malta Independent. 7th December, 2010.

Dendil taz-zaqq wara it-tqala.  Kullhadd Newspaper.  28th November, 2010. Page 22.

Paternita’ bid-DNA legali u mhux legali.  Kullhadd Newspaper. 14th November, 2010.  Page 22.

Kolesterol gholi. Kullhadd Newspaper. 24th October, 2010. Page 22.

Allergiji Stagjonali.  Kullhadd Newspaper. 10th October, 2010. Page 22.

Allergiji mill-halib.  Kullhadd Newspaper.  19th September, 2010.  Page 23.

Problema li qed taffetwalu l-hajja sesswali.  Kullhadd Newspaper.  12th September, 2010. Page 23.

Motor Neurone Disease.  Kullhadd Newspaper. 29th August, 2010.  Page 24.

Ugieh fid-dar.  Kullhadd Newspaper. 22nd August, 2010. Page 23.

Tamiet godda gejjin mill-kurdun ta’ tarbija gdida. Kullhadd Newspaper.  22nd August, 2010. Page 21.

Artrite u wgiegh fl-ghonq.  Kullhadd Newspaper. 15th August, 2010. Page. 23.

Umbilical cords may now provide health insurance. Sunday Times. 8th August, 2010. Page 9.

Is-sajf u l-problemi tieghu.  Kullhadd Newspaper. 8th August, 2010. Page 23.

Il-problema tas-sigaretti.  Kullhadd Newspaper. 1st August, 2010. Page 23.

Kura ghad-dijabete bil-istem cells.  Kullhadd Newspaper. 25th July, 2010. Page 23.

Ugigh fis-sider kull xahar.  Kullhadd Newspaper.  18th July, 2010. Page 23.

Nuqqas ta’ memorja.  Kullhadd Newspaper. 11th July, 2010. Page 23.

Fwied Mahmug.  Kullhadd Newspaper. 4th July, 2010.  Page 23.

Problema dwar piz zejjed.  Kullhadd Newspaper. 27th June, 2010. Page 22.

Dry Bowel Movement.  Kullhadd Newspaper. 20th June, 2010. Page 23.

Il-Hirschsprung Disease.  Kullhadd Newspaper. 13th June, 2010. Page 23.

Problema ta’ cravings.  Kullhadd Newspaper.  22nd May, 2010. Page 23.

Telfien ta’ xaghar.  Kullhadd Newspaper.  16th May, 2010.  Page 23.

L-uzu tal-istem cells. Kullhadd Newspaper. 9th May, 2010. Page 23.

Stress, ugiegh u dwejjaq ta’ kull xahar. Kullhadd Newspaper. 18th April, 2010. Page 24.

Meta koppja ma jistax ikollhom tfal. Kullhadd Newspaper. 11st April, 2010. Page 22.

Tama ghal min ibati bl-Alzheimers.  Kullhadd Newspaper. 21st March, 2010. Page 22.

Nuqqas ta’ rqad. Kullhadd Newspaper. 14th March, 2010. Page 22.

Id-diabete. KullHadd Newspaper. 21st February, 2010. Page 22.

Problema fin-nisa waqt il-menopawsa.  KullHadd Newspaper. 14th February, 2010. Page 22.

Parkinson’s Disease u kura permezz ta’ stem cells.  KullHadd Newspaper.  22nd January, 2010. Page 22.

Problema fl-isports. KullHadd Newspaper. 17th January, 2010. Page 22.

Is-Celebral Palsy. KullHadd Newspaper. 10th January, 2010. Page 22.

Trattament ta’ mard bl-uzu ta’ Stem Cells. KullHadd Newspaper. 20th December, 2009. Page 18.

Tfal morda kif jaqleb it-temp. KullHadd Newspaper. 13th December, 2009. Page 26.

Meta l-protata ma tahdimx kif suppost. KullHadd Newspaper. 29th November, 2009. Page 16.

L-Ilma fil-Gisem.  KullHadd Newspaper. KullHadd Newspaper. 22nd November, 2009.  Page 22.

Pressjoni tad-demm gholja.  KullHadd Newspaper.  15th November, 2009.  Page 22.

Il-vini tas-saqajn.  KullHadd Newspaper. 8th November, 2009. Page 22.

X’inhu l-kolesterol? KullHadd Newspaper. 25th October, 2009. Page 18.

Kura tas-sahha mentali.  KullHadd Newspaper. 18th October, 2009. Page 18.

Maltese biochemist heading major research in stem cell treatment. Sunday Times of Malta. 11th October, 2009. Page 6.

Allergiji mill-ikel. KullHadd Newspaper. 11th October, 2009. Page 22.

Gilda, xaghar u dwiefer ahjar.  KullHadd Newspaper. 4th October, 2009. Page 22.

Spinta lill-ormoni fin-nisa. KullHadd Newspaper. 27th September, 2009. Page 25.

Inflammatory Bowel Disease. KullHadd Newspaper. 20th September, 2009. Page 26.

X’nifhmu bl-impotenza? KullHadd Newspaper. 13th September, 2009. Page 22.

Kif izzid u ssahhah l-immunita’. KullHadd Newspaper. 5th September, 2009. Page 22.

Fibromyalgia Syndrome.  KullHadd Newspaper. 30th August, 2009. Page 24.

Infezzjoni fil-kanal ta’ l-awrina.  KullHadd Newspaper. 23rd August, 2009. Page 24.

Il-problema ta’ l-acne. KullHadd Newspaper. 16th August, 2009. Page 22

Cirkulazzjoni tajba tad-demm fil-gisem. KullHadd Newspaper. 9th August. Page 22.

Ehles mill-hxuna. KullHadd Newspaper. 2nd August, 2009. Page 22.

Protezzjoni mis-Swine Flu. KullHadd Newspaper. 26th July, 2009. Page 26.

Arthrities. KullHadd Newspaper. 19th July, 2009. Page 22.

Infertilita’ fl-irgiel.  KullHadd Newspaper. 12th July, 2009. Page 22.

Stress, ugiegh ta’ ras, dipressjoni u panic attacks.  KullHadd Newspaper. 28th June, 2009. Page 16.

Kif tevita rih, influwenza u infezzjoni.  KullHadd Newspaper. 21st June, 2009. Page 18.

Meta ma tkunx tista’ torqod. KullHadd Newspaper. 14th June, 2009. page 22

L-Uzu ta’ hxejjex natural. KullHadd Newspaper. 31st May, 1009, page 18

L-uzu ta’ Stem Cells.  KullHadd Newspaper. 24th May, 2009, page 20

Id-DNA uzat fil-Forensika.  KullHadd Newspaper. 17th May, 2009, page 21

It-test tal-Paternity. KullHadd Newspaper. 10th May, 2009, page 17

Ic-Celloli u jien. KullHadd Newspaper. 26th April, 2009, page 30

Id-DNA tal-bniedem. KullHadd Newspaper. 19th April, 2009, page 16

DNA. Manic Magazine - The Malta Independent.  30th October, 2008, page 21.

DNA Paternity Testing. Alive and Healthy Magazine 27th April, 2008, page 71.

Stem Cells – A gift for life! Alive and Healthy Magazine 27th April, 2008, page 70.

Are you eating GM products? The Times Of Malta 15th March, 2008, page 19.

The right for DNA paternity testing!  The Malta Independent on Sunday 25th July. 2008, page 19.

Who’s your daddy? The Malta Independent on Sunday 15th June, 2008, page 41.

Books

Blundell, R. (2011) L’imhabba taht il-lenti. ISBN 978-9990-94451-8

Blundell, R. (2011) DNA, Celloli Staminali u Kura b’mod naturali. ISBN 978-9990-94449-5

Others

Blundell, R. (2002) The role of p21 in regulation of injury response in lung epithelial cells. Ph.D. Thesis. Faculty of Medicine, Department of Pathology, University of Edinburgh.

Blundell, R. (1998) Preliminary genome mapping of the Maltese Goat.  M.Phil Thesis.  Faculty of Medicine, Department of Pathology, University of Malta.

Blundell, R., Hunter T., Hunter G., Felice, A.E., (1998) Capra hircus hircus clone 7 RAPD sequence, genomic survey sequence.  Genbank  AF078174.

Blundell, R., Hunter T., Hunter G., Felice, A.E., (1998) Capra hircus hircus clone 12 RAPD sequence, genomic survey sequence, using forward primer.  Genbank  AF078175.

Blundell, R., Hunter T., Hunter G., Felice, A.E., (1998) Capra hircus hircus clone 12 RAPD sequence, genomic survey sequence, using reverse primer.  Genbank  AF078176.

Blundell, R., Hunter T., Hunter G., Felice, A.E., (1998) Capra hircus hircus clone 27 RAPD sequence, genomic survey sequence, using forward primer.  Genbank  AF078177.

Blundell, R., Hunter T., Hunter G., Felice, A.E., (1998) Capra hircus hircus clone 27 RAPD sequence, genomic survey sequence, using reverse primer.  Genbank  AF078178.

Blundell, R., Hunter T., Hunter G., Felice, A.E., (1998) Capra hircus hircus clone 8 RAPD sequence, genomic survey sequence.  Genbank  AF078170.

Blundell, R., Hunter T., Hunter G., Felice, A.E., (1998) Capra hircus hircus clone 22 RAPD sequence, genomic survey sequence.  Genbank  AF078171.

Blundell, R., Hunter T., Hunter G., Felice, A.E., (1998) Capra hircus hircus clone 23 RAPD sequence, genomic survey sequence.  Genbank  AF078172.

Blundell, R., Hunter T., Hunter G., Felice, A.E., (1998) Capra hircus hircus clone 26 RAPD sequence, genomic survey sequence.  Genbank  AF078173.

Blundell, R.; (1994) A Study on Legionella isolated from freshwater habitats. B.Sc.  Faculty of Science, Department of Biology, University of Malta.

Dr N Vassallo

Vassallo, N. and Scerri, C. Mediterranean diet and dementia of the Alzheimer type. Curr. Aging. Sci. [Epub ahead of print]

Hogen, T., Levin, J., Schmidt, F., Caruana, M., Vassallo, N., Kretzschmar, H., Botzel, K., Kamp, F. and Giese, A. (2012) Two different binding modes of alpha-synuclein to lipid vesicles depending on its aggregation state. Biophys J, 102, 1646-1655.

Caruana, M., Neuner, J., Hogen, T., Schmidt, F., Kamp, F., Scerri, C., Giese, A. and Vassallo, N. (2012) Polyphenolic compounds are novel protective agents against lipid membrane damage by alpha-synuclein aggregates in vitro. Biochim Biophys Acta. (Biomembranes), 1818, 2502-2510.

Caruana, M. and Vassallo, N. (2012) The potential role of dietary polyphenols in Parkinson's disease. Malta Medical Journal, 23, 52-55.

Huls, S., Hogen, T., Vassallo, N., Danzer, K. M., Hengerer, B., Giese, A. and Herms, J. (2011) AMPA-receptor-mediated excitatory synaptic transmission is enhanced by iron-induced alpha-synuclein oligomers. J Neurochem, 117, 868-878.

Gauci, A. J., Caruana, M., Giese, A., Scerri, C. and Vassallo, N. (2011) Identification of polyphenolic compounds and black tea extract as potent inhibitors of lipid membrane destabilization by Abeta aggregates. J Alzheimers Dis, 27, 767-779.

Caruana, M., Hogen, T., Levin, J., Hillmer, A., Giese, A. and Vassallo, N. (2011) Inhibition and disaggregation of alpha-synuclein oligomers by natural polyphenolic compounds. FEBS Lett, 585, 1113-1120.

Vassallo, N. (2009) Properties and pathogenicity of prion-derived peptides. Protein Pept Lett, 16, 230-238.

Priller, C., Mitteregger, G., Paluch, S., Vassallo, N., Staufenbiel, M., Kretzschmar, H. A., Jucker, M. and Herms, J. (2009) Excitatory synaptic transmission is depressed in cultured hippocampal neurons of APP/PS1 mice. Neurobiol Aging, 30, 1227-1237.

Vassallo, N. (2008) Polyphenols and Health - New and Recent Advances. Nova Publishers, New York.

Priller, C., Dewachter, I., Vassallo, N., Paluch, S., Pace, C., Kretzschmar, H. A., Van Leuven, F. and Herms, J. (2007) Mutant presenilin 1 alters synaptic transmission in cultured hippocampal neurons. J Biol Chem, 282, 1119-1127.

Krebs, B., Wiebelitz, A., Balitzki-Korte, B., Vassallo, N., Paluch, S., Mitteregger, G., Onodera, T., Kretzschmar, H. A. and Herms, J. (2007) Cellular prion protein modulates the intracellular calcium response to hydrogen peroxide. J Neurochem, 100, 358-367.

Hamid, R., Kilger, E., Willem, M. et al. (2007) Amyloid precursor protein intracellular domain modulates cellular calcium homeostasis and ATP content. J Neurochem, 102, 1264-1275.

Vassallo, N. and Herms, J. (2006) Prion proteins in signal transduction. New Research in Signal Transduction, Nova Publishers, New York.

Krebs, B., Dorner-Ciossek, C., Schmalzbauer, R., Vassallo, N., Herms, J. and Kretzschmar, H. A. (2006) Prion protein induced signaling cascades in monocytes. Biochem Biophys Res Commun, 340, 13-22.

Vassallo, N., Herms, J., Behrens, C., Krebs, B., Saeki, K., Onodera, T., Windl, O. and Kretzschmar, H. A. (2005) Activation of phosphatidylinositol 3-kinase by cellular prion protein and its role

in cell survival. Biochem Biophys Res Commun, 332, 75-82.

Dr T Hunter

Hunter, G. J., and Hunter, T. (2013) GroESL protects superoxide dismutase (SOD)-Deficient cells against oxidative stress and is a chaperone for SOD, Health 5, 1719-1729.

Marita Vella, T. H., Claude Farrugia, Arwen Pearson and Gary Hunter. (2014) Purification and characterisation of xanthin oxidoreductases from local bovids in Malta, Advances in Enzyme Research 2, 54-63.

Gary Hunter, M. V., Rosalin Bonetta, DIane Farrugia, Therese Hunter. (2014) The Structure of Protein Molecules: In celebration of the International Year of Crystallography, Xjenza 2, 43-48.

Kazarjan, J., Vaher, M., Hunter, T., Kulp, M., Hunter, G. J., Bonetta, R., Farrugia, D., and Kaljurand, M. (2015) Determination of metal content in superoxide dismutase enzymes by capillary electrophoresis, Journal of separation science 38, 1042-1045.

Hunter, G. J., Trinh, C. H., Bonetta, R., Stewart, E. E., Cabelli, D. E., and Hunter, T. (2015) The structure of the Caenorhabditis elegans manganese superoxide dismutase MnSOD-3-azide complex, Protein Sciences 24, 1777-1788.

Calendar
Notices
Freshers’ Orientation Agenda 2015
Freshers’ Orientation Agenda 2015
 
 
Last Updated: 6 March 2017

Log In back to UoM Homepage