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Study-Unit Description
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TITLE Renal Physiology and Haematology

LEVEL 01 - Year 1 in Modular Undergraduate Course


DEPARTMENT Physiology and Biochemistry

DESCRIPTION Renal Physiology

1. General Instructional Objectives
    • An understanding of the function of the kidneys and their control
    • An understanding of the chemistry and physiology of acid-base balance in the body and the application of this knowledge to clinical situations

2. Required Abilities
    a. To describe the functional anatomy of the kidneys
    b. To describe glomerular filtration and tubular function
    c. To explain the counter-current mechanisms in the kidney
    d. To explain the mechanisms involved in the regulation of renal function
    e. To outline the endocrine functions of the kidney
    f. To describe the role of the kidneys in the maintenance of acid/base balance
    g. To describe the role of the kidneys in the maintenance of fluid and electrolyte balance
    h. To describe the role of the kidneys in the maintenance of osmolality
    i. To describe the role of the kidney in the handling of glucose and nitrogenous products
    j. To describe the principles of measurement of glomerular filtration rate and renal blood flow
    k. To describe the physiological effects and clinical assessment of renal dysfunction
    l. To explain the renal responses to hypovolaemia
    m. To describe the chemistry of buffer mechanisms and to explain their relevant roles in the body
    n. To describe the regulation of acid-base balance


1. General Instructional Objectives
    • An understanding of the normal physiology of blood and its constituents
    • An understanding of basic immunological principles
    • An understanding of the mechanisms of haemostasis and coagulation

2. Required Abilities
    a. To outline the constituents and functions of plasma
    b. To outline the production of blood constituents including red blood cells, haemoglobin, and plasma proteins
    c. To describe abnormal haemoglobins and their clinical significance
    d. To describe the constituents and physiology of the white blood cell group
    e. To describe passive and active immunity
    f. To use basic immunological principles to explain how the body defends against infection
    g. To describe the role of complement
    h. To explain the origin and importance of blood groups
    i. To describe platelets and their role in coagulation
    j. To describe the intrinsic and extrinsic coagulation pathways
    k. To describe the normal mechanisms of preventing thrombosis including endothelial factors and natural anticoagulants
    l. To describe fibrinolysis and its regulation


Assessment Component/s Resit Availability Weighting
Examination (2 Hours) Yes 100%

LECTURER/S Rosienne Farrugia
Christian Scerri (Co-ord.)

The University makes every effort to ensure that the published Courses Plans, Programmes of Study and Study-Unit information are complete and up-to-date at the time of publication. The University reserves the right to make changes in case errors are detected after publication.
The availability of optional units may be subject to timetabling constraints.
Units not attracting a sufficient number of registrations may be withdrawn without notice.
It should be noted that all the information in the study-unit description above applies to the academic year 2017/8, if study-unit is available during this academic year, and may be subject to change in subsequent years.

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