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MSc Project on offer
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MSc (Chemistry) by Research

Title: Targeted and ultrasensitive nanoparticle-based assays for heart function evaluation via cardiac biomarkers

Supervisor: Prof Emmanuel Sinagra

The development and optimisation of metallic nanoparticles as a part of feasibility study as part of a larger project of constructing a novel colorimetric based diagnostic tool that enables quantitative multiplexed detection of circulating microRNA (miRNA). The assays developed will aim for multiplexing, high sensitivity and excellent specificity, which in turn allow the monitoring of CVD patients with the added advantage of being a non-invasive technique. The assay will be designed in a way that by facile modification of the plasmonic nanoparticles it can be eventually ‘tuned’ to detect other biomarkers (e.g. antigens and aberrantly methylated cell-free DNA) thus obtaining a multi-species sensing platform, which can therefore be readily employed in a clinical setting.

There is a grant for consumables.

Applicants need to hold or hope to achieve a BSc  (Hons) degree with Chemistry as a main area of study classified as 2.2.

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MSc Project on offer

Targeted and ultrasensitive nanoparticle-based assays for heart function evaluation via cardiac biomarkers.
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