Study-Unit Description

Study-Unit Description


TITLE Renal Physiology and Haematology

LEVEL 01 - Year 1 in Modular Undergraduate Course


DEPARTMENT Physiology and Biochemistry

DESCRIPTION Important aspects and fundamental concepts of normal renal function and haematology provide the core material of the unit. Emphasis is placed on the clinical relevance of important physiologic principles.

Study-unit Aims:

This unit aims at providing students in the biomedical sciences with an integrated approach to study of the urinary systems and haematology, hence:
(i) a basic understanding of how the renal system functions in health and disease;
(iii) an introduction to haematology and haemopoeisis and the function of blood cells and other components.

Learning Outcomes:

1. Knowledge & Understanding:
By the end of the study-unit the student will be able to:

- outline factors determining glomerular filtration and its autoregulation;
- highlight transport mechanisms responsible for NaCl and water reabsorption by the nephron;
- discuss the major hormones regulating NaCl and water reabsorption in the kidneys and their sites of action: renin-angiotensin-aldosterone system, atrial natriuretic factor, and antidiuretic hormone;
- describe the role of loop of Henle and vasa recta in production of a dilute and concentrated urine;
- define the effective circulating volume and mechanisms by which body maintains its homeostasis;
- describe the regulation of plasma K+ and Na+ levels by hormones;
- comprehend the principles of acid-base homeostasis;
- comprehend the role of the Blood stem cell in the formation of all blood components;
- be able to identify the function of the blood cells;
- be able to comprehend cascade pathways such as the complement system and coagulation.

2. Skills:
By the end of the study-unit the student will be able to:

- interpret inulin and creatinine clearance to measure glomerular filtration in patients;
- assess patients with renal disease, including oedematous states, disorders of water balances, glomerular diseases, renal failure, ureteric pain, and urinary tract infections;
- interpret normal blood counts;
- identify possible coagulation deficiencies;
- understand the role of the blood cells, compliment system and vascular endothelium in the inflammation.

Main Text/s and any supplementary readings:

Main text:
"Textbook of Medical Physiology" (Ed. Guyton & Hall; Saunders) - or equivalent main physiology textbook.


Assessment Component/s Resit Availability Weighting
Examination (1 Hour) Yes 100%

LECTURER/S Rosienne Farrugia
Christian Scerri (Co-ord.)

The University makes every effort to ensure that the published Courses Plans, Programmes of Study and Study-Unit information are complete and up-to-date at the time of publication. The University reserves the right to make changes in case errors are detected after publication.
The availability of optional units may be subject to timetabling constraints.
Units not attracting a sufficient number of registrations may be withdrawn without notice.
It should be noted that all the information in the study-unit description above applies to the academic year 2017/8, if study-unit is available during this academic year, and may be subject to change in subsequent years.