Browsing by Author Scicluna, Brendon P.

Jump to: 0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
or enter first few letters:  
Showing results 1 to 115 of 115
Issue DateTitleAuthor(s)
2021Adherence affects monocyte innate immune function and metabolic reprogramming after lipopolysaccharide stimulation in vitroOtto, Natasja A.; Butler, Joe M.; Ramirez Moral, Ivan; Weeghel, Michel van; Heijst, Jeroen W. J. van; Scicluna, Brendon P.; Houtkooper, Riekelt H.; Vos, Alex F. de; Poll, Tom van der
2018The adhesion G protein-coupled receptor GPR97/ADGRG3 is expressed in human granulocytes and triggers antimicrobial effector functionsHsiao, Cheng-Chih; Chu, Tai-Ying; Wu, Chia-Jung; Biggelaar, Maartje van den; Pabst, Caroline; Hébert, Josée; Kuijpers, Taco W.; Scicluna, Brendon P.; Yu, Kuan; Chen, Tse-Ching; Liebscher, Ines; Hamann, Jörg; Lin, Hsi-Hsien
2016Admission hyperglycemia in critically ill sepsis patients : association with outcome and host responseVught, Lonneke A. van; Wiewel, Maryse A.; Klein Klouwenberg, Peter M.C.; Hoogendijk, Arie J.; Scicluna, Brendon P.; Ong, David S.Y.; Cremer, Olaf L.; Horn, Janneke; Bonten, Marc M.J.; Schultz, Marcus J.; Poll, Tom van der; Molecular Diagnosis and Risk Stratification of Sepsis (MARS) Consortium
2021Alveolar epithelial TET2 is not involved in the development of bleomycin-induced pulmonary fibrosisQin, Wanhai; Crestani, Bruno; Arnold Spek, C.; Scicluna, Brendon P.; Poll, Tom van der; Duitman, JanWillem
2021Apc-mutant cells act as supercompetitors in intestinal tumour initiationNeerven, Sanne M. van; Groot, Nina E. de; Nijman, Lisanne E.; Scicluna, Brendon P.; Driel, Milou S. van; Lecca, Maria C.; Warmerdam, Daniël O.; Kakkar, Vaishali; Moreno, Leandro F.; Vieira Braga, Felipe A.; Sanches, Delano R.; Ramesh, Prashanthi; Ten Hoorn, Sanne; Aelvoet, Arthur S.; Boxel, Marouska F. van; Koens, Lianne; Krawczyk, Przemek M.; Koster, Jan; Dekker, Evelien; Medema, Jan Paul; Winton, Douglas J.; Bijlsma, Maarten F.; Morrissey, Edward; Léveillé, Nicolas; Vermeulen, Louis
2018Are histones real pathogenic agents in sepsis?Poll, Tom van der; Veerdonk, Frank L. van de; Scicluna, Brendon P.; Netea, Mihai G.
2022Association between age and the host response in critically ill patients with sepsisMichels, Erik H.A.; Butler, Joe M.; Reijnders, Tom D.Y.; Cremer, Olaf L.; Scicluna, Brendon P.; Uhel, Fabrice; Peters-Sengers, Hessel; Schultz, Marcus J.; Knight, Julian C.; Vught, Lonneke A. van; Poll, Tom van der; MARS consortium
2021Association between delay in intensive care unit admission and the host response in patients with community-acquired pneumoniaPereverzeva, Liza; Uhel, Fabrice; Peters-Sengers, Hessel; Cremer, Olaf L.; Schultz, Marcus J.; Bonten, Marc M.J.; Scicluna, Brendon P.; Poll, Tom van der; MARS Consortium
2016Association of diabetes and diabetes treatment with the host response in critically ill sepsis patientsVught, Lonneke A. van; Scicluna, Brendon P.; Hoogendijk, Arie J.; Wiewel, Maryse A.; Klein Klouwenberg, Peter M.C.; Cremer, Olaf L.; Horn, Janneke; Nürnberg, Peter; Bonten, Marc M.J.; Schultz, Marcus J.; Poll, Tom van der
2017Association of gender with outcome and host response in critically ill sepsis patientsVught, Lonneke A. van; Scicluna, Brendon P.; Wiewel, Maryse A.; Hoogendijk, Arie J.; Klein Klouwenberg, Peter M.C.; Ong, David S.Y.; Cremer, Olaf L.; Horn, Janneke; Franitza, Marek; Toliat, Mohammad Reza; Nürnberg, Peter; Bonten, Marc M.J.; Schultz, Marcus J.; Poll, Tom van der; MARS Consortium
2022Association of hyperferritinemia with distinct host response aberrations in patients with community-acquired pneumoniaBrands, Xanthe; Engelen, Tjitske S.R. van; Vries, Floris M. C. de; Haak, Bastiaan W.; Klarenbeek, Augustijn M.; Kanglie, Maadrika M. N. P.; Berk, Inge A. H. van den; Schuurman, Alex R.; Peters-Sengers, Hessel; Otto, Natasja A.; Faber, Daniël R.; Lutter, René; Scicluna, Brendon P.; Stoker, Jaap; Prins, Jan M.; Joost Wiersinga, W.; Poll, Tom van der
2022Bacterial and viral respiratory tract microbiota and host characteristics in adults with lower respiratory tract infections : a case-control studyHaak, Bastiaan W.; Brands, Xanthe; Davids, Mark; Peters-Sengers, Hessel; Kullberg, Robert F. J.; Houdt, Robin van; Hugenholtz, Floor; Faber, Daniël R.; Zaaijer, Hans L.; Scicluna, Brendon P.; Poll, Tom van der; Joost Wiersinga, W.
2021Biological subphenotypes of acute respiratory distress syndrome show prognostic enrichment in mechanically ventilated patients without acute respiratory distress syndromeHeijnen, Nanon F. L.; Hagens, Laura A.; Smit, Marry R.; Cremer, Olaf L.; Ong, David S.Y.; Poll, Tom van der; Vught, Lonneke A. van; Scicluna, Brendon P.; Schnabel, Ronny M.; Horst, Iwan C. C. van der; Schultz, Marcus J.; Bergmans, Dennis C. J. J.; Bos, Lieuwe D. J.
2021Biological subphenotypes of ARDS show prognostic enrichment in mechanically ventilated patients without ARDSHeijnen, Nanon F. L.; Hagens, Laura A.; Smit, Marry R.; Cremer, Olaf L.; Ong, David S.Y.; Poll, Tom van der; Vught, Lonneke A. van; Scicluna, Brendon P.; Schnabel, Ronny M.; Horst, Iwan C. C. van der; Schultz, Marcus J.; Bergmans, Dennis C. J. J.; Bos, Lieuwe D. J.
2018Biomarkers in sepsisEngelen, Tjitske S. R. van; Joost Wiersinga, Willem; Scicluna, Brendon P.; Poll, Tom van der
2022Blood leukocyte transcriptomes in Gram-positive and Gram-negative community-acquired pneumoniaPereverzeva, Liza; Uhel, Fabrice; Peters-Sengers, Hessel; Butler, Joe M.; Vught, Lonneke A. van; Burnham, Katie L.; Davenport, Emma E.; Knight, Julian C.; Cremer, Olaf L.; Schultz, Marcus J.; Bonten, Marc M.J.; Scicluna, Brendon P.; Poll, Tom van der; MARS Consortium
2016Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsisCheng, Shih-Chin; Scicluna, Brendon P.; Arts, Rob J.W.; Gresnigt, Mark S.; Lachmandas, Ekta; Giamarellos-Bourboulis, Evangelos J.; Kox, Matthijs; Manjeri, Ganesh R.; Wagenaars, Jori A. L.; Cremer, Olaf L.; Leentjens, Jenneke; Meer, Anne-Jan van der; Veerdonk, Frank L. van de; Bonten, Marc M.J.; Schultz, Marcus J.; Willems, Peter H. G. M.; Pickkers, Peter; Joosten, Leo A.B.; Poll, Tom van der; Netea, Mihai G.
2021Bronchial epithelial DNA methyltransferase 3b dampens pulmonary immune responses during pseudomonas aeruginosa infectionQin, Wanhai; Brands, Xanthe; Veer, Cornelis Van't; Vos, Alex F. de; Sirard, Jean-Claude; Roelofs, Joris J. T. H.; Scicluna, Brendon P.; Poll, Tom van der
2020Bronchial epithelial Tet2 maintains epithelial integrity during acute pseudomonas aeruginosa pneumoniaQin, Wanhai; Brands, Xanthe; Veer, Cornelis Van't; Vos, Alex F. de; Scicluna, Brendon P.; Poll, Tom van der
2009The cardiac sodium channel displays differential distribution in the conduction system and transmural heterogeneity in the murine ventricular myocardiumRemme, Carol Ann; Verkerk, Arie O.; Hoogaars, W. M. H.; Aanhaanen, W. T. J.; Scicluna, Brendon P.; Annink, C.; Hoff, Maurice J. B. van den; Wilde, Arthur A. M.; Veen, T. A. B. van; Veldkamp, Marieke W.; Bakker, Jacques M. T. de; Christoffels, V. M.; Bezzina, Connie R.
2015Chemokine ligand 9 modulates cardiac repolarization via Cxcr3 receptor bindingScicluna, Brendon P.; Remme, Carol Ann; Rivaud, Mathilde; Wilde, Arthur A. M.; Bezzina, Connie R.; Verkerk, Arie O.
2020The circular RNA landscape in specific peripheral blood mononuclear cells of critically ill patients with sepsisKhan, Hina N.; Brands, Xanthe; Aufiero, Simona; Hoogendijk, Arie J.; Klarenbeek, Augustijn M.; Engelen, Tjitske S.R. van; Haak, Bastiaan W.; Vught, Lonneke A. van; Horn, Janneke; Schultz, Marcus J.; Zwinderman, Aeilko H.; Poll, Tom van der; Scicluna, Brendon P.
2021The circulatory small non-coding RNA landscape in community-acquired pneumonia on intensive care unit admissionKhan, Hina N.; Jongejan, Aldo; Vught, Lonneke A. van; Horn, Janneke; Schultz, Marcus J.; Zwinderman, Aeilko H.; Cremer, Olaf L.; Bonten, Marc M.J.; Poll, Tom van der; Scicluna, Brendon P.
2017Classification of patients with sepsis according to blood genomic endotype : a prospective cohort studyScicluna, Brendon P.; Vught, Lonneke A. van; Zwinderman, Aeilko H.; Wiewel, Maryse A.; Davenport, Emma E.; Burnham, Katie L.; Nürnberg, Peter; Schultz, Marcus J.; Horn, Janneke; Cremer, Olaf L.; Bonten, Marc M.J.; Hinds, Charles J.; Wong, Hector R.; Knight, Julian C.; Poll, Tom van der; MARS Consortium
2018Classification of patients with septic shock : are we there yet?Wittebole, Xavier; Scicluna, Brendon P.
2020The coding and non-coding transcriptional landscape of subependymal giant cell astrocytomasBongaarts, Anika; Scheppingen, Jackelien van; Korotkov, Anatoly; Mijnsbergen, Caroline; Anink, Jasper J.; Jansen, Floor E.; Spliet, Wim G. M.; Dunnen, Wilfred F.A. den; Gruber, Victoria E.; Scholl, Theresa; Samueli, Sharon; Hainfellner, Johannes A.; Feucht, Martha; Kotulska, Katarzyna; Jozwiak, Sergiusz; Grajkowska, Wieslawa; Buccoliero, Anna Maria; Caporalini, Chiara; Giordano, Flavio; Genitori, Lorenzo; Coras, Roland; Blümcke, Ingmar; Krsek, Pavel; Zamecnik, Josef; Meijer, Lisethe; Scicluna, Brendon P.; Schouten-van Meeteren, Antoinette Y. N.; Mühlebner, Angelika; Mills, James D.; Aronica, Eleonora
2017Coding and small non-coding transcriptional landscape of tuberous sclerosis complex cortical tubers : implications for pathophysiology and treatmentMills, James D.; Iyer, Anand M.; Scheppingen, Jackelien van; Bongaarts, Anika; Anink, Jasper J.; Janssen, Bart; Zimmer, Till S.; Spliet, Wim G. M.; Rijen, Peter C. van; Jansen, Floor E.; Feucht, Martha; Hainfellner, Johannes A.; Krsek, Pavel; Zamecnik, Josef; Kotulska, Katarzyna; Jozwiak, Sergiusz; Jansen, Anna; Lagae, Lieven; Curatolo, Paolo; Kwiatkowski, David J.; Jeroen Pasterkamp, R.; Senthilkumar, Ketharini; Oerthel, Lars von; Hoekman, Marco F.; Gorter, Jan A.; Crino, Peter B.; Mühlebner, Angelika; Scicluna, Brendon P.; Aronica, Eleonora
2021Combined transcriptome and proteome leukocyte’s profiling reveals up-regulated module of genes/proteins related to low density neutrophils and impaired transcription and translation processes in clinical sepsisFiguerêido Leite, Giuseppe Gianini; Ferreira, Bianca Lima; Tashima, Alexandre Keiji; Nishiduka, Erika Sayuri; Cunha-Neto, Edecio; Colo Brunialti, Milena Karina; Assuncao, Murillo; Pontes Azevedo, Luciano Cesar; Freitas, Flávio; Poll, Tom van der; Scicluna, Brendon P.; Salomão, Reinaldo
2016Comparative analysis of the host response to community-acquired and hospital-acquired pneumonia in critically ill patientsVught, Lonneke A. van; Scicluna, Brendon P.; Wiewel, Maryse A.; Hoogendijk, Arie J.; Klein Klouwenberg, Peter M.C.; Franitza, Marek; Toliat, Mohammad Reza; Nürnberg, Peter; Cremer, Olaf L.; Horn, Janneke; Schultz, Marcus J.; Bonten, Marc M.J.; Poll, Tom van der
2020Concurrent immune suppression and hyperinflammation in patients with community-acquired pneumoniaBrands, Xanthe; Haak, Bastiaan W.; Klarenbeek, Augustijn M.; Otto, Natasja A.; Faber, Daniël R.; Lutter, René; Scicluna, Brendon P.; Joost Wiersinga, W.; Poll, Tom van der
2021Consumptive coagulopathy is associated with a disturbed host response in patients with sepsisVught, Lonneke A. van; Uhel, Fabrice; Ding, Chao; Veer, Cees Van't; Scicluna, Brendon P.; Peters-Sengers, Hessel; Klein Klouwenberg, Peter M.C.; Nürnberg, Peter; Cremer, Olaf L.; Schultz, Marcus J.; Poll, Tom van der; MARS Consortium
2020Corrigendum : concurrent immune suppression and hyperinflammation in patients with community-acquired pneumoniaBrands, Xanthe; Haak, Bastiaan W.; Klarenbeek, Augustijn M.; Otto, Natasja A.; Faber, Daniël R.; Lutter, René; Scicluna, Brendon P.; Joost Wiersinga, W.; Poll, Tom van der
2012Dissection of a quantitative trait locus for PR interval duration identifies Tnni3k as a novel modulator of cardiac conductionLodder, Elisabeth M.; Scicluna, Brendon P.; Milano, Annalisa; Sun, Albert Y.; Tang, Hao; Remme, Carol Ann; Moerland, Perry D.; Tanck, Michael W.T.; Pitt, Geoffrey S.; Marchuk, Douglas A.; Bezzina, Connie R.
2021Distinct DNA methylation patterns of subependymal giant cell astrocytomas in tuberous sclerosis complexBongaarts, Anika; Mijnsbergen, Caroline; Anink, Jasper J.; Jansen, Floor E.; Spliet, Wim G. M.; Dunnen, Wilfred F.A. den; Coras, Roland; Blümcke, Ingmar; Paulus, Werner; Gruber, Victoria E.; Scholl, Theresa; Hainfellner, Johannes A.; Feucht, Martha; Kotulska, Katarzyna; Jozwiak, Sergiusz; Grajkowska, Wieslawa; Buccoliero, Anna Maria; Caporalini, Chiara; Giordano, Flavio; Genitori, Lorenzo; Söylemezoğlu, Figen; Pimentel, José; Jones, David T. W.; Scicluna, Brendon P.; Schouten-van Meeteren, Antoinette Y. N.; Mühlebner, Angelika; Mills, James D.; Aronica, Eleonora
2022DNA methyltransferase 3b in myeloid cells does not affect the acute immune response in the airways during pseudomonas pneumoniaQin, Wanhai; Brands, Xanthe; Veer, Cornelis Van't; Vos, Alex F. de; Scicluna, Brendon P.; Poll, Tom van der
2020Dysregulation of the MMP/TIMP proteolytic system in subependymal giant cell astrocytomas in patients with tuberous sclerosis complex : modulation of MMP by MicroRNA-320d in vitroBongaarts, Anika; Jong, Jody M. de; Broekaart, Diede W. M.; Scheppingen, Jackelien van; Anink, Jasper J.; Mijnsbergen, Caroline; Jansen, Floor E.; Spliet, Wim G. M.; Dunnen, Wilfred F.A. den; Gruber, Victoria E.; Scholl, Theresa; Hainfellner, Johannes A.; Feucht, Martha; Borkowska, Julita; Kotulska, Katarzyna; Jozwiak, Sergiusz; Grajkowska, Wieslawa; Buccoliero, Anna Maria; Caporalini, Chiara; Giordano, Flavio; Genitori, Lorenzo; Scicluna, Brendon P.; Schouten-van Meeteren, Antoinette Y. N.; Vliet, Erwin A. van; Mühlebner, Angelika; Mills, James D.; Aronica, Eleonora
2014The effect of age on the systemic inflammatory response in patients with community-acquired pneumoniaVught, Lonneke A. van; Endeman, H.; Meijvis, S. C.; Zwinderman, Aeilko H.; Scicluna, Brendon P.; Biesma, D. H.; Poll, Tom van der
2022Effect of intravenous clarithromycin in patients with sepsis, respiratory and multiple organ dysfunction syndrome : a randomized clinical trialKarakike, Eleni; Scicluna, Brendon P.; Roumpoutsou, Maria; Mitrou, Ioannis; Karampela, Niki; Karageorgos, Athanasios; Psaroulis, Konstantinos; Massa, Eleni; Pitsoulis, Achillefs; Chaloulis, Panagiotis; Pappa, Evanthia; Schrijver, Irene T.; Frantzeskaki, Frantzeska; Lada, Malvina; Dauby, Nicolas; Bels, David De; Floros, Ioannis; Anisoglou, Souzana; Antoniadou, Eleni; Patrani, Maria; Vlachogianni, Glykeria; Mouloudi, Eleni; Antoniadou, Anastasia; Grimaldi, David; Roger, Thierry; Joost Wiersinga, W.; Tsangaris, Iraklis; Giamarellos-Bourboulis, Evangelos J.
2020Elevated trefoil factor 3 plasma levels in critically ill patients with abdominal sepsis or non-infectious abdominal illnessMeijer, Mariska T.; Uhel, Fabrice; Cremer, Olaf L.; Scicluna, Brendon P.; Schultz, Marcus J.; Poll, Tom van der; MARS Consortium
2021An epigenetic and transcriptomic signature of immune tolerance in human monocytes through multi-omics integrationBrands, Xanthe; Haak, Bastiaan W.; Klarenbeek, Augustijn M.; Butler, Joe M.; Uhel, Fabrice; Qin, Wanhai; Otto, Natasja A.; Jakobs, Marja E.; Faber, Daniël R.; Lutter, René; Joost Wiersinga, W.; Poll, Tom van der; Scicluna, Brendon P.
2021Flagellin induces innate immune genes in bronchial epithelial cells in vivo : role of TET2Qin, Wanhai; Brands, Xanthe; Veer, Cornelis Van't; Vos, Alex F. de; Scicluna, Brendon P.; Poll, Tom van der
2012Functional Nav1.8 channels in intracardiac neurons : the link between SCN10A and cardiac electrophysiologyVerkerk, Arie O.; Remme, Carol Ann; Schumacher, Cees A.; Scicluna, Brendon P.; Wolswinkel, Rianne; Jonge, Berend de; Bezzina, Connie R.; Veldkamp, Marieke W.
2019Genetic signature related to heme-hemoglobin metabolism pathway in sepsis secondary to pneumoniaFiguerêido Leite, Giuseppe Gianini; Scicluna, Brendon P.; Poll, Tom van der; Salomão, Reinaldo
2009Genetically determined differences in sodium current characteristics modulate conduction disease severity in mice with cardiac sodium channelopathyRemme, Carol Ann; Scicluna, Brendon P.; Verkerk, Arie O.; Amin, Ahmad S.; Brunschot, Sandra van; Beekman, Leander; Deneer, Vera H. M.; Chevalier, Catherine; Oyama, Fumitaka; Miyazaki, Haruko; Nukina, Nobuyuki; Wilders, Ronald; Escande, Denis; Houlgatte, Rémi; Wilde, Arthur A. M.; Tan, Hanno L.; Veldkamp, Marieke W.; Bakker, Jacques M. T. de; Bezzina, Connie R.
2010Genome-wide association study identifies a susceptibility locus at 21q21 for ventricular fibrillation in acute myocardial infarctionBezzina, Connie R.; Pazoki, Raha; Bardai, Abdennasser; Marsman, Roos F.; Jong, Jonas S.S.G. de; Blom, Marieke T.; Scicluna, Brendon P.; Wouter Jukema, J.; Bindraban, Navin R.; Lichtner, Peter; Pfeufer, Arne; Bishopric, Nanette H.; Roden, Dan M.; Meitinger, Thomas; Chugh, Sumeet S.; Myerburg, Robert J.; Jouven, Xavier; Kääb, Stefan; Dekker, Lukas R.C.; Tan, Hanno L.; Tanck, Michael W.T.; Wilde, Arthur A. M.
2017The gut microbiota as a modulator of innate immunity during melioidosisLankelma, Jacqueline M.; Birnie, Emma; Weehuizen, Tassili A. F.; Scicluna, Brendon P.; Belzer, Clara; Houtkooper, Riekelt H.; Roelofs, Joris J. T. H.; Vos, Alex F. de; Poll, Tom van der; Budding, Andries E.; Joost Wiersinga, W.
2016The gut microbiota plays a protective role in the host defence against pneumococcal pneumoniaSchuijt, Tim J.; Lankelma, Jacqueline M.; Scicluna, Brendon P.; Sousa e Melo, Felipe de; Roelofs, Joris J. T. H.; Boer, J. Daan de; Hoogendijk, Arjan J.; Beer, Regina de; Vos, Alex F. de; Belzer, Clara; Vos, Willem M. de; Poll, Tom van der; Joost Wiersinga, W.
2021HIVEP1 is a negative regulator of NF-κB that inhibits systemic inflammation in sepsisMatsumoto, Hisatake; Scicluna, Brendon P.; Jim, Kin Ki; Falahi, Fahimeh; Qin, Wanhai; Gürkan, Berke; Malmström, Erik; Meijer, Mariska T.; Butler, Joe M.; Khan, Hina N.; Takagi, Tsuyoshi; Ishii, Shunsuke; Schultz, Marcus J.; Beek, Diederik van de; Vos, Alex F. de; Veer, Cornelis Van't; Poll, Tom van der
2018The host response in critically ill sepsis patients on statin therapy : a prospective observational studyWiewel, Maryse A.; Scicluna, Brendon P.; Vught, Lonneke A. van; Hoogendijk, Arie J.; Zwinderman, Aeilko H.; Lutter, René; Horn, Janneke; Cremer, Olaf L.; Bonten, Marc M.J.; Schultz, Marcus J.; Poll, Tom van der
2022The host response in different aetiologies of community-acquired pneumoniaSchuurman, Alex R.; Reijnders, Tom D. Y.; Engelen, Tjitske S.R. van; Léopold, Valentine; Brabander, Justin de; Linge, Christine van; Schinkel, Michiel; Pereverzeva, Liza; Haak, Bastiaan W.; Brands, Xanthe; Kanglie, Maadrika M. N. P.; Berk, Inge A. H. van den; Douma, Renée A.; Faber, Daniël R.; Nanayakkara, Prabath W. B.; Stoker, Jaap; Prins, Jan M.; Scicluna, Brendon P.; Joost Wiersinga, W.; Poll, Tom van der
2017The host response in patients with sepsis developing intensive care unit–acquired secondary infectionsVught, Lonneke A. van; Wiewel, Maryse A.; Hoogendijk, Arie J.; Frencken, Jos F.; Scicluna, Brendon P.; Klein Klouwenberg, Peter M.C.; Zwinderman, Aeilko H.; Lutter, René; Horn, Janneke; Schultz, Marcus J.; Bonten, Marc M.J.; Cremer, Olaf L.; Poll, Tom van der
2019Human adipose-derived mesenchymal stem cells modify lung immunity and improve antibacterial defense in pneumosepsis caused by Klebsiella pneumoniaePerlee, Desirée; Vos, Alex F. de; Scicluna, Brendon P.; Mancheño, Pablo; Rosa, Olga de la; Dalemans, Wilfried; Nürnberg, Peter; Lombardo, Eleuterio; Poll, Tom van der
2015IFN-γ priming of macrophages represses a part of the inflammatory program and attenuates neutrophil recruitmentHoeksema, Marten A.; Scicluna, Brendon P.; Boshuizen, Marieke C. S.; Velden, Saskia van der; Neele, Annette E.; Bossche, Jan Van den; Matlung, Hanke L.; Berg, Timo K. van den; Goossens, Pieter; Winther, Menno P. J. de
2022An immune dysfunction score for stratification of patients with acute infection based on whole-blood gene expressionCano-Gamez, Eddie; Burnham, Katie L.; Goh, Cyndi; Allcock, Alice; Malick, Zunaira H.; Overend, Lauren; Kwok, Andrew; Smith, David A.; Peters-Sengers, Hessel; Antcliffe, David; McKechnie, Stuart; Hall, Sally; Addison, Jenni; Roughton, Sian; Tennant, Heather; Guleri, Achyut; Waddington, Natalia; Arawwawala, Dilshan; Durcan, John; Short, Alasdair; Swan, Karen; Raymode, Parizade; Williams, Sarah; Smolen, Susan; Mitchell-Inwang, Christine; Gordon, Tony; Errington, Emily; Templeton, Maie; Venatesh, Pyda; Ward, Geraldine; McCauley, Marie; Baudouin, Simon; Thompson, Jonathan; Higham, Charley; Soar, Jasmeet; Grier, Sally; Hall, Elaine; Brett, Stephen; Kitson, David; Wilson, Robert; Mountford, Laura; Moreno, Juan; Hall, Peter; Bowrey, Sarah; Hewlett, Jackie; McKechnie, Stuart; Garrard, Christopher; Millo, Julian; Young, Duncan; Hutton, Paula; Parsons, Penny; Smiths, Alex; Faras-Arraya, Roser; Soar, Jasmeet; Kazembe, Sandra; Rich, Natalie; Andreou, Prem; Hales, Dawn; Roberts, Emma; Fletcher, Simon; Rosbergen, Melissa; Lowes, Sarah; Glister, Georgina; Moreno Cuesta, Jeronimo; Bion, Julian; Millar, Joanne; Perry, Elsa Jane; Willis, Heather; Mitchell, Natalie; Ruel, Sebastian; Carrera, Ronald; Wilde, Jude; Higham, Charley; Nilson, Annette; Lees, Sarah; Kapila, Atul; Jacques, Nicola; Atkinson, Jane; Brown, Abby; Prowse, Heather; Krige, Anton; Bland, Martin; Bullock, Lynne; Walsh, Helen; Harrison, Donna; Mills, Gary; Humphreys, John; Armitage, Kelsey; Laha, Shond; Baldwin, Jacqueline; Walsh, Angela; Doherty, Nicola; Drage, Stephen; Ortiz-Ruiz de Gordoa, Laura; Calder, Verity; Swan, Catherine; Payne, Heather; Higgins, David; Andrews, Sarah; Mappleback, Sarah; Hind, Charles; Scicluna, Brendon P.; Garrard, Chris; Watson, D.; McLees, Eleanor; Purdy, Alice; Stotz, Martin; Ochelli-Okpue, Adaeze; Bonner, Stephen; Whitehead, Iain; Hugil, Keith; Goodridge, Victoria; Poll, Tom van der; Cawthor, Louisa; Kuper, Martin; Pahary, Sheik; Bellingan, Geoffrey; Marshall, Richard; Montgomery, Hugh; Hyun Ryu, Jung; Bercades, Georgia; Boluda, Susan; Bentley, Andrew; Gordon, Anthony C.; Mccalman, Katie; Jefferies, Fiona; Knight, Julian; Davenport, Emma; Burnham, Katie L.; Maugeri, Narelle; Radhakrishnan, Jayachandran; Mi, Yuxin; Allcock, Alice; Goh, Cyndi; Hinds, Charles J.; Davenport, Emma E.; Knight, Julian C.; Webster, Nigel; Galley, Helen; Taylor, Jane; GAinS Investigators
2022Immune suppression is associated with enhanced systemic inflammatory, endothelial and procoagulant responses in critically ill patientsBrands, Xanthe; Uhel, Fabrice; Vught, Lonneke A. van; Wiewel, Maryse A.; Hoogendijk, Arie J.; Lutter, René; Schultz, Marcus J.; Scicluna, Brendon P.; Poll, Tom van der
2017The immunopathology of sepsis and potential therapeutic targetsPoll, Tom van der; Veerdonk, Frank L. van de; Scicluna, Brendon P.; Netea, Mihai G.
2016The impact of HIV co-infection on the genomic response to sepsisHuson, Michaëla A. M.; Scicluna, Brendon P.; Vught, Lonneke A. van; Wiewel, Maryse A.; Hoogendijk, Arie J.; Cremer, Olaf L.; Bonten, Marc M.J.; Schultz, Marcus J.; Franitza, Marek; Toliat, Mohammad Reza; Nürnberg, Peter; Grobusch, Martin P.; Poll, Tom van der
2016Incidence, risk factors, and attributable mortality of secondary infections in the intensive care unit after admission for sepsisVught, Lonneke A. van; Klein Klouwenberg, Peter M.C.; Spitoni, Cristian; Scicluna, Brendon P.; Wiewel, Maryse A.; Horn, Janneke; Schultz, Marcus J.; Nürnberg, Peter; Bonten, Marc M.J.; Cremer, Olaf L.; Poll, Tom van der; MARS Consortium
2021Integrated single-cell analysis unveils diverging immune features of COVID-19, influenza, and other community-acquired pneumoniaSchuurman, Alex R.; Reijnders, Tom D. Y.; Saris, Anno; Ramirez Moral, Ivan; Schinkel, Michiel; Brabander, Justin de; Linge, Christine van; Vermeulen, Louis; Scicluna, Brendon P.; Joost Wiersinga, W.; Vieira Braga, Felipe A.; Poll, Tom van der
2014Integrative genomic approach identifies multiple genes involved in cardiac collagen depositionLodder, Elisabeth M.; Scicluna, Brendon P.; Beekman, Leander; Arends, Danny; Moerland, Perry D.; Tanck, Michael W.T.; Adriaens, Michiel E.; Bezzina, Connie R.
2012Interleukin-27 : a potential new sepsis biomarker exposed through genome-wide transcriptional profilingScicluna, Brendon P.; Poll, Tom van der
2022Intracellular pyruvate levels positively correlate with cytokine production capacity in tolerant monocytes from patients with pneumoniaOtto, Natasja A.; Butler, Joe M.; Schuurman, Alex R.; Brands, Xanthe; Haak, Bastiaan W.; Klarenbeek, Augustijn M.; Weeghel, Michel van; Houtkooper, Riekelt H.; Jakobs, Marja E.; Faber, Daniël R.; Vos, Alex F. de; Joost Wiersinga, W.; Scicluna, Brendon P.; Poll, Tom van der
2018Intravenous infusion of human adipose mesenchymal stem cells modifies the host response to lipopolysaccharide in humans : a randomized, single-blind, parallel group, placebo controlled trialPerlee, Desirée; Vught, Lonneke A. van; Scicluna, Brendon P.; Maag, Anja; Lutter, René; Kemper, Elles M.; Veer, Cornelis Van't; Punchard, Marie A.; González, Jesús; Richard, Marie Paule; Dalemans, Wilfried; Lombardo, Eleuterio; Vos, Alex F. de; Poll, Tom van der
2019The itaconate pathway is a central regulatory node linking innate immune tolerance and trained immunityDomínguez-Andrés, Jorge; Novakovic, Boris; Li, Yang; Scicluna, Brendon P.; Gresnigt, Mark S.; Arts, Rob J.W.; Oosting, Marije; Moorlag, Simone J.C.F.M.; Groh, Laszlo A.; Zwaag, Jelle; Koch, Rebecca M.; Horst, Robter; Joosten, Leo A.B.; Wijmenga, Cisca; Michelucci, Alessandro; Poll, Tom van der; Kox, Matthijs; Pickkers, Peter; Kumar, Vinod; Stunnenber, Henk; Netea, Mihai G.
2019Kinase activity is impaired in neutrophils of sepsis patientsHoogendijk, Arie J.; Vught, Lonneke A. van; Wiewel, Maryse A.; Fuhler, Gwenny M.; Belkasim-Bohoudi, Hakima; Horn, Janneke; Schultz, Marcus J.; Scicluna, Brendon P.; Peppelenbosch, Maikel P.; Veer, Cornelis Van't; Vos, Alex F. de; Poll, Tom van der
2020The leukocyte non-coding RNA landscape in critically ill patients with sepsisScicluna, Brendon P.; Uhel, Fabrice; Vught, Lonneke A. van; Wiewel, Maryse A.; Hoogendijk, Arie J.; Baessman, Ingelore; Franitza, Marek; Nürnberg, Peter; Horn, Janneke; Cremer, Olaf L.; Bonten, Marc M.J.; Schultz, Marcus J.; Poll, Tom van der; Molecular Diagnosis and Risk Stratification of Sepsis (MARS) Consortium
2019Leukocyte transcriptional signatures dependent on LPS dosage in human endotoxemiaKhan, Hina N.; Perlee, Desirée; Schoenmaker, Lieke; Meer, Anne-Jan van der; Franitza, Marek; Toliat, Mohammad Reza; Nürnberg, Peter; Zwinderman, Aeilko H.; Poll, Tom van der; Scicluna, Brendon P.
2011Load-reducing therapy prevents development of arrhythmogenic right ventricular cardiomyopathy in plakoglobin-deficient miceFabritz, Larissa; Hoogendijk, Mark G.; Scicluna, Brendon P.; Amersfoorth, Shirley C.M. van; Fortmueller, Lisa; Wolf, Susanne; Laakmann, Sandra; Kreienkamp, Nina; Piccini, Ilaria; Breithardt, Günter; Ruiz Noppinger, Patricia; Witt, Henning; Ebnet, Klaus; Wichter, Thomas; Levkau, Bodo; Franke, Werner W.; Pieperhoff, Sebastian; Bakker, Jacques M. T. de; Coronel, Ruben; Kirchhof, Paulus
2022The long non-coding antisense RNA JHDM1D-AS1 regulates inflammatory responses in human monocytesMalmström, Erik; Khan, Hina N.; Veer, Cornelis van’t; Stunnenberg, Melissa; Meijer, Mariska T.; Matsumoto, Hisatake; Otto, Natasja A.; Geijtenbeek, Teunis B. H.; Vos, Alex F. de; Poll, Tom van der; Scicluna, Brendon P.
2019Matrix metalloproteinase-8 : a useful biomarker to refine the diagnosis of community-acquired pneumonia upon intensive care unit admission?Uhel, Fabrice; Scicluna, Brendon P.; Vught, Lonneke A. van; Cremer, Olaf L.; Bonten, Marc M.J.; Schultz, Marcus J.; Poll, Tom van der
2015Modular transcriptional networks of the host pulmonary response during early and late pneumococcal pneumoniaScicluna, Brendon P.; Lieshout, Miriam H. van; Blok, Dana C.; Florquin, Sandrine; Poll, Tom van der
2018Molecular biomarker to assist in diagnosing abdominal sepsis upon ICU admissionScicluna, Brendon P.; Wiewel, Maryse A.; Vught, Lonneke A. van; Hoogendijk, Arie J.; Klarenbeek, Augustijn M.; Franitza, Marek; Toliat, Mohammad Reza; Nürnberg, Peter; Horn, Janneke; Bonten, Marc M.J.; Schultz, Marcus J.; Cremer, Olaf L.; Poll, Tom van der
2015A molecular biomarker to diagnose community-acquired pneumonia on intensive care unit admissionScicluna, Brendon P.; Klein Klouwenberg, Peter M.C.; Vught, Lonneke A. van; Wiewel, Maryse A.; Ong, David S.Y.; Zwinderman, Aeilko H.; Franitza, Marek; Toliat, Mohammad Reza; Nürnberg, Peter; Hoogendijk, Arie J.; Horn, Janneke; Cremer, Olaf L.; Schultz, Marcus J.; Bonten, Marc M.J.; Poll, Tom van der
2015A molecular host response assay to discriminate between sepsis and infection-negative systemic inflammation in critically ill patients : discovery and validation in independent cohortsMcHugh, Leo C.; Seldon, Therese A.; Brandon, Roslyn A.; Kirk, James T.; Rapisarda, Antony; Sutherland, Allison J.; Presneill, Jeffrey J.; Venter, Deon J.; Lipman, Jeffrey; Thomas, Mervyn R.; Klein Klouwenberg, Peter M.C.; Vught, Lonneke A. van; Scicluna, Brendon P.; Bonten, Marc M.J.; Cremer, Olaf L.; Schultz, Marcus J.; Poll, Tom van der; Yager, Thomas D.; Brandon, Richard B.
2020Mortality and host response aberrations associated with transient and persistent acute kidney injury in critically ill patients with sepsis: a prospective cohort studyUhel, Fabrice; Peters-Sengers, Hessel; Falahi, Fahimeh; Scicluna, Brendon P.; Vught, Lonneke A. van; Bonten, Marc M.J.; Cremer, Olaf L.; Schultz, Marcus J.; Poll, Tom van der; MARS Consortium
2022Myeloid cell tet methylcytosine dioxygenase 2 does not affect the host response during gram-negative bacterial pneumonia and sepsisQin, Wanhai; Brands, Xanthe; Veer, Cornelis Van't; Vos, Alex F. de; Scicluna, Brendon P.; Poll, Tom van der
2022Myeloid DNA methyltransferase3b deficiency aggravates pulmonary fibrosis by enhancing profibrotic macrophage activationQin, Wanhai; Arnold Spek, C.; Scicluna, Brendon P.; Poll, Tom van der; Duitman, JanWillem
2009Myocyte necrosis underlies progressive myocardial dystrophy in mouse dsg2-related arrhythmogenic right ventricular cardiomyopathyPilichou, Kalliopi; Remme, Carol Ann; Basso, Cristina; Campian, Maria E.; Rizzo, Stefania; Barnett, Phil; Scicluna, Brendon P.; Bauce, Barbara; Hoff, Maurice J. B. van den; Bakker, Jacques M. T. de; Tan, Hanno L.; Valente, Marialuisa; Nava, Andrea; Wilde, Arthur A. M.; Moorman, Antoon F. M.; Thiene, Gaetano; Bezzina, Connie R.
2014NLRP3 and ASC differentially affect the lung transcriptome during pneumococcal pneumoniaLieshout, Miriam H. van; Scicluna, Brendon P.; Florquin, Sandrine; Poll, Tom van der
2022Patients with hypothermic sepsis have a unique gene expression profile compared to patients with fever and sepsisHarmon, Matthew B. A.; Scicluna, Brendon P.; Wiewel, Maryse A.; Schultz, Marcus J.; Horn, Janneke; Cremer, Olaf L.; Poll, Tom van der; Joost Wiersinga, W.; Juffermans, Nicole P.; MARS Consortium
2019A pilot study of a novel molecular host response assay to diagnose infection in patients after high-risk gastro-intestinal surgeryVerboom, Diana M.; Koster-Brouwer, Maria E.; Ruurda, Jelle P.; Hillegersberg, Richard van; Berge Henegouwen, Mark I. van; Gisbertz, Suzanne S.; Scicluna, Brendon P.; Bonten, Marc M.J.; Cremer, Olaf L.; MARS Consortium
2021Plasma ferritin as marker of macrophage activation-like syndrome in critically ill patients with community-acquired pneumoniaBrands, Xanthe; Vries, Floris M. C. de; Uhel, Fabrice; Haak, Bastiaan W.; Peters-Sengers, Hessel; Schuurman, Alex R.; Engelen, Tjitske S.R. van; Lutter, René; Cremer, Olaf L.; Bonten, Marc M.J.; Schultz, Marcus J.; Scicluna, Brendon P.; Poll, Tom van der; MARS Consortium
2015Plasma fractalkine is a sustained marker of disease severity and outcome in sepsis patientsHoogendijk, Arie J.; Wiewel, Maryse A.; Vught, Lonneke A. van; Scicluna, Brendon P.; Belkasim-Bohoudi, Hakima; Horn, Janneke; Zwinderman, Aeilko H.; Klein Klouwenberg, Peter M.C.; Cremer, Olaf L.; Bonten, Marc M.J.; Schultz, Marcus J.; Poll, Tom van der; MARS Consortium
2020Prekallikrein inhibits innate immune signaling in the lung and impairs host defense during pneumosepsis in miceDing, Chao; Scicluna, Brendon P.; Stroo, Ingrid; Yang, Jack; Roelofs, Joris J. T. H.; Boer, Onno J. de; Vos, Alex F. de; Nürnberg, Peter; Revenko, Alexey S.; Crosby, Jeff; Veer, Cornelis Van't; Poll, Tom van der
2008The primary arrhythmia syndromes : same mutation, different manifestations. Are we starting to understand why?Scicluna, Brendon P.; Wilde, Arthur A. M.; Bezzina, Connie R.
2017Prior use of calcium channel blockers is associated with decreased mortality in critically ill patients with sepsis : a prospective observational studyWiewel, Maryse A.; Vught, Lonneke A. van; Scicluna, Brendon P.; Hoogendijk, Arie J.; Frencken, Jos F.; Zwinderman, Aeilko H.; Horn, Janneke; Cremer, Olaf L.; Bonten, Marc M.J.; Schultz, Marcus J.; Poll, Tom van der; Molecular Diagnosis and Risk Stratification of Sepsis (MARS) Consortium
2021Protease-activated receptor 1 drives and maintains ductal cell fates in the premalignant pancreas and ductal adenocarcinomaTekin, Cansu; Scicluna, Brendon P.; Lodestijn, Sophie C.; Shi, Kun; Bijlsma, Maarten F.; Arnold Spek, C.
2003Proteomic detection of globin gene expression nuclear factors : implementation of an HPLC-CE two-dimensional separation system.Scicluna, Brendon P.
2011Quantitative trait loci for electrocardiographic parameters and arrhythmia in the mouseScicluna, Brendon P.; Tanck, Michael W.T.; Remme, Carol Ann; Beekman, Leander; Coronel, Ruben; Wilde, Arthur A. M.; Bezzina, Connie R.
2021Rectal bacteriome and virome signatures and clinical outcomes in community-acquired pneumonia : an exploratory studyKullberg, Robert F. J.; Hugenholtz, Floor; Brands, Xanthe; Kinsella, Cormac M.; Peters-Sengers, Hessel; Butler, Joe M.; Deijs, Martin; Klein, Michelle; Faber, Daniël R.; Scicluna, Brendon P.; Poll, Tom van der; Hoek, Lia Van der; Joost Wiersinga, W.; Haak, Bastiaan W.
2022Rectal microbiota are coupled with altered cytokine production capacity following community-acquired pneumonia hospitalizationKullberg, Robert F.J.; Brands, Xanthe; Klarenbeek, Augustijn M.; Butler, Joe M.; Otto, Natasja A.; Faber, Daniël R.; Scicluna, Brendon P.; Poll, Tom van der; Joost Wiersinga, W.; Haak, Bastiaan W.
2015Reduced responsiveness of blood leukocytes to lipopolysaccharide does not predict nosocomial infections in critically ill patientsVught, Lonneke A. van; Wiewel, Maryse A.; Hoogendijk, Arie J.; Scicluna, Brendon P.; Belkasim-Bohoudi, Hakima; Horn, Janneke; Schultz, Marcus J.; Poll, Tom van der
2015Reply : comprehensive validation of the FAIM3:PLAC8 ratio in time-matched public gene expression dataScicluna, Brendon P.; Klein Klouwenberg, Peter M.C.; Poll, Tom van der
2016Reply : FAIM3:PLAC8 ratio compared with existing biomarkers for diagnosis of severe community-acquired pneumonia: comparing apples to oranges?Scicluna, Brendon P.; Vught, Lonneke A. van; Poll, Tom van der; Klein Klouwenberg, Peter M.C.; Cremer, Olaf L.
2022Resolving patient heterogeneity in critical illness requires multi-scale approachesScicluna, Brendon P.
2016Risk factors, host response and outcome of hypothermic sepsisWiewel, Maryse A.; Harmon, Matthew B.; Vught, Lonneke A. van; Scicluna, Brendon P.; Hoogendijk, Arie J.; Horn, Janneke; Zwinderman, Aeilko H.; Cremer, Olaf L.; Bonten, Marc M.J.; Schultz, Marcus J.; Poll, Tom van der; Juffermans, Nicole P.; Joost Wiersinga, W.
2021The role of host cell DNA methylation in the immune response to bacterial infectionQin, Wanhai; Scicluna, Brendon P.; Poll, Tom van der
2021Role of myeloid Tet methylcytosine dioxygenase 2 in pulmonary and peritoneal inflammation induced by lipopolysaccharide and peritonitis induced by Escherichia coliQin, Wanhai; Brands, Xanthe; Matsumoto, Hisatake; Butler, Joe M.; Veer, Cornelis Van't; Vos, Alex F. de; Roelofs, Joris J. T. H.; Scicluna, Brendon P.; Poll, Tom van der
2019Role of tissue factor in the procoagulant and antibacterial effects of human adipose-derived mesenchymal stem cells during pneumosepsis in micePerlee, Desirée; Vos, Alex F. de; Scicluna, Brendon P.; Maag, Anja; Mancheño, Pablo; Rosa, Olga de la; Dalemans, Wilfried; Florquin, Sandrine; Veer, Cornelis Van't; Lombardo, Eleuterio; Poll, Tom van der
2013Role of tumor necrosis factor-α in the human systemic endotoxin-induced transcriptomeScicluna, Brendon P.; Veer, Cornelis Van't; Nieuwdorp, Max; Felsmann, Karen; Wlotzka, Britta; Stroes, Erik S.G.; Poll, Tom van der
2019The search for efficacious new therapies in sepsis needs to embrace heterogeneityScicluna, Brendon P.; Kenneth Baillie, J.
2015The selective sirtuin 1 activator SRT2104 reduces endotoxin-induced cytokine release and coagulation activation in humansMeer, Anne-Jan van der; Scicluna, Brendon P.; Moerland, Perry D.; Lin, Jiang; Jacobson, Eric W.; Vlasuk, George P.; Poll, Tom van der
2017Sepsis patients display a reduced capacity to activate nuclear factor-κB in multiple cell typesHoogendijk, Arie J.; Garcia-Laorden, M. Isabel; Vught, Lonneke A. van; Wiewel, Maryse A.; Belkasim-Bohoudi, Hakima; Willem Duitman, Jan; Horn, Janneke; Schultz, Marcus J.; Scicluna, Brendon P.; Veer, Cornelis Van't; Vos, Alex F. de; Poll, Tom van der
2021Sepsis subclasses : a framework for development and interpretationDeMerle, Kimberley M.; Angus, Derek C.; Kenneth Baillie, J.; Brant, Emily; Calfee, Carolyn S.; Carcillo, Joseph; Chang, Chung-Chou H.; Dickson, Robert; Evans, Idris; Gordon, Anthony C.; Kennedy, Jason; Knight, Julian C.; Lindsell, Christopher J.; Liu, Vincent; Marshall, John C.; Randolph, Adrienne G.; Scicluna, Brendon P.; Shankar-Hari, Manu; Shapiro, Nathan I.; Sweeney, Timothy E.; Talisa, Victor B.; Tang, Benjamin; Taylor Thompson, B.; Tsalik, Ephraim L.; Poll, Tom van der; Vught, Lonneke A. van; Wong, Hector R.; Yende, Sachin; Zhao, Huiying; Seymour, Christopher W.
2022Source-specific host response and outcomes in critically ill patients with sepsis : a prospective cohort studyPeters-Sengers, Hessel; Butler, Joe M.; Uhel, Fabrice; Schultz, Marcus J.; Bonten, Marc M.J.; Cremer, Olaf L.; Scicluna, Brendon P.; Vught, Lonneke A. van; Poll, Tom van der; MARS Consortium
2021Steroid-resistant human inflammatory ILC2s are marked by CD45RO and elevated in type 2 respiratory diseasesPloeg, Esmee K. van der; Golebski, Korneliusz; Nimwegen, Menno van; Fergusson, Joannah R.; Heesters, Balthasar A.; Martinez-Gonzalez, Itziar; Kradolfer, Chantal M.A.; Tol, Sophie van; Scicluna, Brendon P.; Bruijn, Marjolein J.W. de; Boer, Geertje M. de; Tramper-Stranders, Gerdien A.; Braunstahl, Gert-Jan; IJcken, Wilfred F.J. van; Paul Nagtegaal, A.; Drunen, Cornelis M. van; Fokkens, Wytske J.; Huylebroeck, Danny; Spits, Hergen; Hendriks, Rudi W.; Stadhouders, Ralph; Bal, Suzanne M.
2021Tenascin C has a modest protective effect on acute lung pathology during methicillin-resistant staphylococcus aureus-induced pneumonia in miceMeijer, Mariska T.; Vos, Alex F. de; Peters-Sengers, Hessel; Scicluna, Brendon P.; Roelofs, Joris J. T. H.; Fayçal, Chérine Abou; Uhel, Fabrice; Orend, Gertraud; Poll, Tom van der
2021Tenascin-C deficiency is associated with reduced bacterial outgrowth during Klebsiella pneumoniae-evoked pneumosepsis in miceMeijer, Mariska T.; Vos, Alex F. de; Scicluna, Brendon P.; Roelofs, Joris J. T. H.; Abou Fayçal, Chérine; Orend, Gertraud; Uhel, Fabrice; Poll, Tom van der
2016Thrombocytopenia is associated with a dysregulated host response in critically ill sepsis patientsClaushuis, Theodora A. M.; Vught, Lonneke A. van; Scicluna, Brendon P.; Wiewel, Maryse A.; Klein Klouwenberg, Peter M.C.; Hoogendijk, Arie J.; Ong, David S.Y.; Cremer, Olaf L.; Horn, Janneke; Franitza, Marek; Toliat, Mohammad Reza; Nürnberg, Peter; Zwinderman, Aeilko H.; Bonten, Marc M.J.; Schultz, Marcus J.; Poll, Tom van der; Molecular Diagnosis and Risk Stratification of Sepsis (MARS) Consortium
2021Transcriptional changes in alveolar macrophages from adults with asthma after allergen challengeYang, Jack; Scicluna, Brendon P.; Engelen, Tjitske S.R. van; Bonta, Peter I.; Majoor, Christof J.; Veer, Cornelis Van't; Vos, Alex F. de; Bel, Elisabeth H.; Poll, Tom van der
2010Tubulin polymerization modifies cardiac sodium channel expression and gatingCasini, Simona; Tan, Hanno L.; Demirayak, Ilker; Remme, Carol Ann; Amin, Ahmad S.; Scicluna, Brendon P.; Chatyan, Houssine; Ruijter, Jan M.; Bezzina, Connie R.; Ginneken, Antoni C. G. van; Veldkamp, Marieke W.
2017Turning a new page in sepsis molecular diagnostics necessitates context-specific biomarkersScicluna, Brendon P.; Poll, Tom van der
2019Understanding heterogeneity in biologic phenotypes of acute respiratory distress syndrome by leukocyte expression profilesBos, Lieuwe D. J.; Scicluna, Brendon P.; Ong, David S.Y.; Cremer, Olaf L.; Poll, Tom van der; Schultz, Marcus J.
2018Validation of a host response assay, septicyte LAB, for discriminating sepsis from systemic inflammatory response syndrome in the ICUMiller 3rd, Russell R.; Lopansri, Bert K.; Burke, John P.; Levy, Mitchell; Opal, Steven; Rothman, Richard E.; D'Alessio, Franco R.; Sidhaye, Venkataramana K.; Aggarwal, Neil R.; Balk, Robert; Greenberg, Jared A.; Yoder, Mark; Patel, Gourang; Gilbert, Emily; Afshar, Majid; Parada, Jorge P.; Martin, Greg S.; Esper, Annette M.; Kempker, Jordan A.; Narasimhan, Mangala; Tsegaye, Adey; Hahn, Stella; Mayo, Paul; Poll, Tom van der; Schultz, Marcus J.; Scicluna, Brendon P.; Klein Klouwenberg, Peter M.C.; Rapisarda, Antony; Seldon, Therese A.; McHugh, Leo C.; Yager, Thomas D.; Cermelli, Silvia; Sampson, Dayle; Rothwell, Victoria; Newman, Richard; Bhide, Shruti; Fox, Brian A.; Kirk, James T.; Navalkar, Krupa; Davis, Roy F.; Brandon, Roslyn A.; Brandon, Richard B.
2018Validation of a novel molecular host response assay to diagnose infection in hospitalized patients admitted to the ICU with acute respiratory failureKoster-Brouwer, Maria E.; Verboom, Diana M.; Scicluna, Brendon P.; Groep, Kirsten van de; Frencken, Jos F.; Janssen, Davy; Schuurman, Rob; Schultz, Marcus J.; Poll, Tom van der; Bonten, Marc M.J.; Cremer, Olaf L.; MARS Consortium