Browsing by Author Scicluna, Brendon P.

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Issue DateTitleAuthor(s)
2021Rectal bacteriome and virome signatures and clinical outcomes in community-acquired pneumonia : an exploratory studyKullberg, Robert F. J.; Hugenholtz, Floor; Brands, Xanthe; Kinsella, Cormac M.; Peters-Sengers, Hessel; Butler, Joe M.; Deijs, Martin; Klein, Michelle; Faber, Daniël R.; Scicluna, Brendon P.; Poll, Tom van der; Hoek, Lia Van der; Joost Wiersinga, W.; Haak, Bastiaan W.
2022Rectal microbiota are coupled with altered cytokine production capacity following community-acquired pneumonia hospitalizationKullberg, Robert F.J.; Brands, Xanthe; Klarenbeek, Augustijn M.; Butler, Joe M.; Otto, Natasja A.; Faber, Daniël R.; Scicluna, Brendon P.; Poll, Tom van der; Joost Wiersinga, W.; Haak, Bastiaan W.
2015Reduced responsiveness of blood leukocytes to lipopolysaccharide does not predict nosocomial infections in critically ill patientsVught, Lonneke A. van; Wiewel, Maryse A.; Hoogendijk, Arie J.; Scicluna, Brendon P.; Belkasim-Bohoudi, Hakima; Horn, Janneke; Schultz, Marcus J.; Poll, Tom van der
2015Reply : comprehensive validation of the FAIM3:PLAC8 ratio in time-matched public gene expression dataScicluna, Brendon P.; Klein Klouwenberg, Peter M.C.; Poll, Tom van der
2016Reply : FAIM3:PLAC8 ratio compared with existing biomarkers for diagnosis of severe community-acquired pneumonia: comparing apples to oranges?Scicluna, Brendon P.; Vught, Lonneke A. van; Poll, Tom van der; Klein Klouwenberg, Peter M.C.; Cremer, Olaf L.
2022Resolving patient heterogeneity in critical illness requires multi-scale approachesScicluna, Brendon P.
2016Risk factors, host response and outcome of hypothermic sepsisWiewel, Maryse A.; Harmon, Matthew B.; Vught, Lonneke A. van; Scicluna, Brendon P.; Hoogendijk, Arie J.; Horn, Janneke; Zwinderman, Aeilko H.; Cremer, Olaf L.; Bonten, Marc M.J.; Schultz, Marcus J.; Poll, Tom van der; Juffermans, Nicole P.; Joost Wiersinga, W.
2021The role of host cell DNA methylation in the immune response to bacterial infectionQin, Wanhai; Scicluna, Brendon P.; Poll, Tom van der
2021Role of myeloid Tet methylcytosine dioxygenase 2 in pulmonary and peritoneal inflammation induced by lipopolysaccharide and peritonitis induced by Escherichia coliQin, Wanhai; Brands, Xanthe; Matsumoto, Hisatake; Butler, Joe M.; Veer, Cornelis Van't; Vos, Alex F. de; Roelofs, Joris J. T. H.; Scicluna, Brendon P.; Poll, Tom van der
2019Role of tissue factor in the procoagulant and antibacterial effects of human adipose-derived mesenchymal stem cells during pneumosepsis in micePerlee, Desirée; Vos, Alex F. de; Scicluna, Brendon P.; Maag, Anja; Mancheño, Pablo; Rosa, Olga de la; Dalemans, Wilfried; Florquin, Sandrine; Veer, Cornelis Van't; Lombardo, Eleuterio; Poll, Tom van der
2013Role of tumor necrosis factor-α in the human systemic endotoxin-induced transcriptomeScicluna, Brendon P.; Veer, Cornelis Van't; Nieuwdorp, Max; Felsmann, Karen; Wlotzka, Britta; Stroes, Erik S.G.; Poll, Tom van der
2019The search for efficacious new therapies in sepsis needs to embrace heterogeneityScicluna, Brendon P.; Kenneth Baillie, J.
2015The selective sirtuin 1 activator SRT2104 reduces endotoxin-induced cytokine release and coagulation activation in humansMeer, Anne-Jan van der; Scicluna, Brendon P.; Moerland, Perry D.; Lin, Jiang; Jacobson, Eric W.; Vlasuk, George P.; Poll, Tom van der
2017Sepsis patients display a reduced capacity to activate nuclear factor-κB in multiple cell typesHoogendijk, Arie J.; Garcia-Laorden, M. Isabel; Vught, Lonneke A. van; Wiewel, Maryse A.; Belkasim-Bohoudi, Hakima; Willem Duitman, Jan; Horn, Janneke; Schultz, Marcus J.; Scicluna, Brendon P.; Veer, Cornelis Van't; Vos, Alex F. de; Poll, Tom van der
2021Sepsis subclasses : a framework for development and interpretationDeMerle, Kimberley M.; Angus, Derek C.; Kenneth Baillie, J.; Brant, Emily; Calfee, Carolyn S.; Carcillo, Joseph; Chang, Chung-Chou H.; Dickson, Robert; Evans, Idris; Gordon, Anthony C.; Kennedy, Jason; Knight, Julian C.; Lindsell, Christopher J.; Liu, Vincent; Marshall, John C.; Randolph, Adrienne G.; Scicluna, Brendon P.; Shankar-Hari, Manu; Shapiro, Nathan I.; Sweeney, Timothy E.; Talisa, Victor B.; Tang, Benjamin; Taylor Thompson, B.; Tsalik, Ephraim L.; Poll, Tom van der; Vught, Lonneke A. van; Wong, Hector R.; Yende, Sachin; Zhao, Huiying; Seymour, Christopher W.
2022Source-specific host response and outcomes in critically ill patients with sepsis : a prospective cohort studyPeters-Sengers, Hessel; Butler, Joe M.; Uhel, Fabrice; Schultz, Marcus J.; Bonten, Marc M.J.; Cremer, Olaf L.; Scicluna, Brendon P.; Vught, Lonneke A. van; Poll, Tom van der; MARS Consortium
2021Steroid-resistant human inflammatory ILC2s are marked by CD45RO and elevated in type 2 respiratory diseasesPloeg, Esmee K. van der; Golebski, Korneliusz; Nimwegen, Menno van; Fergusson, Joannah R.; Heesters, Balthasar A.; Martinez-Gonzalez, Itziar; Kradolfer, Chantal M.A.; Tol, Sophie van; Scicluna, Brendon P.; Bruijn, Marjolein J.W. de; Boer, Geertje M. de; Tramper-Stranders, Gerdien A.; Braunstahl, Gert-Jan; IJcken, Wilfred F.J. van; Paul Nagtegaal, A.; Drunen, Cornelis M. van; Fokkens, Wytske J.; Huylebroeck, Danny; Spits, Hergen; Hendriks, Rudi W.; Stadhouders, Ralph; Bal, Suzanne M.
2021Tenascin C has a modest protective effect on acute lung pathology during methicillin-resistant staphylococcus aureus-induced pneumonia in miceMeijer, Mariska T.; Vos, Alex F. de; Peters-Sengers, Hessel; Scicluna, Brendon P.; Roelofs, Joris J. T. H.; Fayçal, Chérine Abou; Uhel, Fabrice; Orend, Gertraud; Poll, Tom van der
2021Tenascin-C deficiency is associated with reduced bacterial outgrowth during Klebsiella pneumoniae-evoked pneumosepsis in miceMeijer, Mariska T.; Vos, Alex F. de; Scicluna, Brendon P.; Roelofs, Joris J. T. H.; Abou Fayçal, Chérine; Orend, Gertraud; Uhel, Fabrice; Poll, Tom van der
2016Thrombocytopenia is associated with a dysregulated host response in critically ill sepsis patientsClaushuis, Theodora A. M.; Vught, Lonneke A. van; Scicluna, Brendon P.; Wiewel, Maryse A.; Klein Klouwenberg, Peter M.C.; Hoogendijk, Arie J.; Ong, David S.Y.; Cremer, Olaf L.; Horn, Janneke; Franitza, Marek; Toliat, Mohammad Reza; Nürnberg, Peter; Zwinderman, Aeilko H.; Bonten, Marc M.J.; Schultz, Marcus J.; Poll, Tom van der; Molecular Diagnosis and Risk Stratification of Sepsis (MARS) Consortium