https://www.um.edu.mt/library/oar/handle/123456789/27487 2026-04-04T17:20:49Z 2026-04-04T17:20:49Z Vella, Cecil Calleja Stafrace, Damien https://www.um.edu.mt/library/oar/handle/123456789/15448 2019-10-15T08:11:36Z 2016-01-01T00:00:00Z

Title: Tuberous sclerosis associated with multiple hepatic lipomatous tumours Authors: Vella, Cecil; Calleja Stafrace, Damien Abstract: Tuberous sclerosis is a genetic multisystem disorder characterised by widespread hamartomas in several organs, including brain, heart, skin, eyes, kidney, lung and liver. Hepatic multiple angiomyolipomas (AML’s) are a rare and usually asymptomatic complication in patients with tuberous sclerosis. We present such a case. We report a 15 year old girl with tuberous sclerosis who was noted to have multiple AML’s of the liver and kidneys found on routine ultrasound screening. She was asymptomatic at this stage and in view of the small size of the AML’s a repeat ultrasound of the liver and kidneys was performed twelve months later

2016-01-01T00:00:00Z Muratori, Davide Meani, Paolo Quattrocchi, Giuseppina Pedrotti, Patrizia https://www.um.edu.mt/library/oar/handle/123456789/15445 2018-01-26T13:20:06Z 2016-01-01T00:00:00Z

Title: Association of unicuspid unicommissural aortic valve and complex congenital heart disease depicted by cardiac magnetic resonance Authors: Muratori, Davide; Meani, Paolo; Quattrocchi, Giuseppina; Pedrotti, Patrizia Abstract: A 12-year-old male child was referred for follow-up cardiac magnetic resonance (CMR) of complex congenital heart disease, characterized by aortic decoarctation, interventricular and interatrial septal defects (VSD and ASD) closure and bicuspid aortic valve.

2016-01-01T00:00:00Z Micallef Eynaud, Stephen Attard Montalto, Simon Grech, Victor E. https://www.um.edu.mt/library/oar/handle/123456789/15444 2018-01-04T14:43:21Z 2016-01-01T00:00:00Z

Title: A case of atypical Kawasaki disease with giant coronary artery aneurysm containing thrombus Authors: Micallef Eynaud, Stephen; Attard Montalto, Simon; Grech, Victor E. Abstract: Kawasaki disease (KD) is an acute febrile, systemic vasculitic syndrome of unknown etiology, occurring primarily in children younger than 5 years of age. Administration of IVIG within the first 10 days after onset of fever in combination with high dose aspirin reduces the risk of coronary artery damage in KD. Though rare, giant aneurysms of the coronary arteries may develop in untreated cases and prove extremely challenging to manage. A 9-month-old Caucasian boy presented to our paediatric emergency department with a 4-week history of intermittent pyrexia and irritability. Typical mucocutaneous signs of Kawasaki Disease were absent upon presentation. A trans-thoracic echocardiogram identified a giant aneurysm of the left anterior descending artery with thrombus formation in-situ and the child was managed with intravenous immunoglobulin, steroids, high dose aspirin therapy and later warfarinisation. Cardiovascular sequelae of Kawasaki disease include giant coronary artery aneurysms with thrombosis. Enlargement of a coronary aneurysm after the acute phase of Kawasaki disease is uncommon and the outcome of interventional approaches poorly studied.

2016-01-01T00:00:00Z Bugeja, Justine Cutajar, D. Zahra, C. Parascandalo, Raymond Grech, Victor E. De Giovanni, Joseph V. https://www.um.edu.mt/library/oar/handle/123456789/15442 2018-04-18T12:36:51Z 2016-01-01T00:00:00Z

Title: Aortic stenting for neonatal coarctation of the aorta : when should this be considered? Authors: Bugeja, Justine; Cutajar, D.; Zahra, C.; Parascandalo, Raymond; Grech, Victor E.; De Giovanni, Joseph V. Abstract: Aortic coarctation (CoA) constitutes the fifth most common congenital heart defect (1 in 2500 live births). This lesion comprises 5-8% of congenital heart disease and has variable severity and mode of presentation. Critical coarctation in newborns usually presents with severe narrowing of the upper thoracic aorta below the isthmus and adjacent to the arterial duct, and is dependent on duct patency for survival. Rapid deterioration of the patient usually results from spontaneous closure of the patent arterial duct (PDA). This deterioration is in part due to reduced renal perfusion resulting in fluid and acid retention causing heart failure and metabolic acidosis. This may be alleviated by the administration of intravenous prostaglandin, with temporary improvement of distal aortic blood flow, and overall condition. The treatment of choice is surgical resection with the ‘extended end-to-end’ technique. We present a case of a severely ill newborn with complex coarctation, multiorgan failure, disseminated intravascular coagulation and oedema, who was treated with emergency stenting on the tenth day of life. This was followed by surgical stent removal and repair of the arch on the 29th day of life. We followed the strategy of minimally invasive interventional bridging of a borderline patient with regard to the experience of stenting of native coarctations in older patients, or complex recurrent stenosis of previously surgically treated children

2016-01-01T00:00:00Z