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  <title>OAR@UM Collection:</title>
  <link rel="alternate" href="https://www.um.edu.mt/library/oar/handle/123456789/28030" />
  <subtitle />
  <id>https://www.um.edu.mt/library/oar/handle/123456789/28030</id>
  <updated>2026-04-06T23:44:07Z</updated>
  <dc:date>2026-04-06T23:44:07Z</dc:date>
  <entry>
    <title>The effect of exercise on the gait biomechanics of the neuro-ischemic diabetic foot with peripheral neuropathy</title>
    <link rel="alternate" href="https://www.um.edu.mt/library/oar/handle/123456789/34107" />
    <author>
      <name />
    </author>
    <id>https://www.um.edu.mt/library/oar/handle/123456789/34107</id>
    <updated>2018-09-28T01:47:56Z</updated>
    <published>2017-01-01T00:00:00Z</published>
    <summary type="text">Title: The effect of exercise on the gait biomechanics of the neuro-ischemic diabetic foot with peripheral neuropathy
Abstract: The aim of the study was to investigate the effect of a six-week exercise program on the kinetics and&#xD;
kinematics during gait in people diagnosed with ischemia and diabetic peripheral neuropathy. The&#xD;
peak plantar pressures, pressure-time integral, lower limb joint angles in the sagittal plane and ground&#xD;
reaction forces were tested before and after the exercise program. Research in this area is lacking,&#xD;
providing only small scale studies with mixed results and decreased significance. The researcher&#xD;
aimed to add to the body of knowledge and provide further insight into the possible use of exercise&#xD;
to prevent and manage the complications of diabetic peripheral neuropathy such as the development&#xD;
of pressure ulcers.&#xD;
Methodology: Twelve participants were chosen for this pilot study, and were asked to carry out a&#xD;
specialised exercise program for six weeks, twice weekly. The kinematics and ground reaction forces&#xD;
were tested using 3D motion analysis (Vicon) and force plates (AMTI) and plantar pressures and&#xD;
pressure-time integral were tested via the TekScan HR mat. The patients acted as their own control,&#xD;
comparing pre- and post- intervention results.&#xD;
Results showed a statistically significant decrease in plantar pressures in all areas and in the pressuretime&#xD;
integral at the forefoot. Hip flexion at toe-off and knee extension at heel strike showed a&#xD;
statistically significant improvement. All other areas showed a slight improvement but were not&#xD;
statistically significant, thus failing to reject the null hypothesis.&#xD;
Conclusion: Although improvements were seen, this pilot study requires further research to support&#xD;
the findings in this study and possibly implement these findings in clinical practice in the future.
Description: M.SC.CLINICAL BIOMECHANICS</summary>
    <dc:date>2017-01-01T00:00:00Z</dc:date>
  </entry>
  <entry>
    <title>A comparison of standard wound care vs. standard wound care with adjunct hyperbaric oxygen therapy in diabetic arterial ulceration</title>
    <link rel="alternate" href="https://www.um.edu.mt/library/oar/handle/123456789/28653" />
    <author>
      <name />
    </author>
    <id>https://www.um.edu.mt/library/oar/handle/123456789/28653</id>
    <updated>2018-04-25T06:35:02Z</updated>
    <published>2017-01-01T00:00:00Z</published>
    <summary type="text">Title: A comparison of standard wound care vs. standard wound care with adjunct hyperbaric oxygen therapy in diabetic arterial ulceration
Abstract: Background: As the incidence of diabetes increases so does the prevalence of diabetic&#xD;
arterial ulcerations, which if not treated promptly, may lead to loss of morbidity posing a&#xD;
great burden on the patient’s quality of life and the health care system. Diverse treatment&#xD;
modalities and protocols for arterial ulcerations are available, however further studies should&#xD;
be conducted to compare and evaluate the clinical efficacy of such treatments.&#xD;
Aim: The aim of this study was to compare Standard Wound Care versus Standard Wound&#xD;
Care with Adjunct Hyperbaric Oxygen Therapy in the treatment of diabetic arterial foot&#xD;
ulceration.&#xD;
Research Design and Method: A quasi-experimental, matched-control clinical trial was&#xD;
conducted at the Tissue Viability Unit and at the Hyperbaric Oxygen Therapy Unit. &#xD;
Twenty-six&#xD;
participants living with Type 2 Diabetes and presenting with a newly diagnosed arterial&#xD;
foot ulcer were recruited. Subjects were divided into 2 groups. Group A underwent Standard&#xD;
Wound Care with adjunct Hyperbaric Oxygen Therapy and Group B underwent Standard&#xD;
Wound Care only. Following application of treatment, participants were reviewed every&#xD;
week for a period of four weeks and their ulcers were measured for their surface area and&#xD;
depth to assess any change in wound size.&#xD;
Results: Both Standard Wound Care with adjunct Hyperbaric Oxygen Therapy and Standard&#xD;
Wound Care only were effective in reducing the surface area and depth of ulcer (p=0.00).&#xD;
Nonetheless, SWC with adjunctive HBOT was 3.57 times better in reducing the surface area&#xD;
(p=0.000) of the ulcer and 4.61 times in reducing the depth of the ulcer (p=0.000) when&#xD;
compared to SWC only.&#xD;
Conclusion: Standard Wound Care with adjunctive Hyperbaric Oxygen Therapy, could be&#xD;
considered as a more practical and effective modality when treating diabetic arterial foot&#xD;
ulcerations, owing to its advantages in reducing the surface area and depth of ulcers in&#xD;
comparison to Standard Wound Care only. Provision of optimal wound care, would promote&#xD;
wound healing, bringing about significant reductions in the number of amputations which&#xD;
will eventually improve the patients’ quality of life and reduce both morbidity and mortality&#xD;
in this high-risk population.
Description: B.SC.(HONS)PODIATRY</summary>
    <dc:date>2017-01-01T00:00:00Z</dc:date>
  </entry>
  <entry>
    <title>The effect of Type 2 Diabetes Mellitus on plantar pressure and contact area within the Maltese population</title>
    <link rel="alternate" href="https://www.um.edu.mt/library/oar/handle/123456789/28373" />
    <author>
      <name />
    </author>
    <id>https://www.um.edu.mt/library/oar/handle/123456789/28373</id>
    <updated>2018-03-29T13:32:13Z</updated>
    <published>2017-01-01T00:00:00Z</published>
    <summary type="text">Title: The effect of Type 2 Diabetes Mellitus on plantar pressure and contact area within the Maltese population
Abstract: Aim :&#xD;
The aim of this study was to determine whether plantar pressure and contact area in&#xD;
participants living with Type 2 Diabetes are affected by the duration of Type 2 Diabetes&#xD;
Mellitus.&#xD;
Research Design and Method : &#xD;
The study employed a non-experimental quantitative matched subject design. A group of 36&#xD;
participants were recruited and divided into three groups (Group 1: 0-5 years, Group 2: 6-&#xD;
10 years, Group 3: 11-15 years) matched for age, gender, weight and duration of diabetes.&#xD;
Foot pressure mapping utilizing the 2-step protocol was employed to obtain the mean peak&#xD;
plantar pressure, mean pressure-time integral and mean contact area for the hallux, 1st&#xD;
metatarsophalangeal joint region, 2nd - 4th metatarsophalangeal joint region, 5th&#xD;
metatarsophalangeal joint region and heel for both feet.&#xD;
Results :&#xD;
The results indicate that there was a significant difference in mean peak plantar pressure&#xD;
between the three groups under the left (p=0.012) and right 2nd - 4th metatarsophalangeal&#xD;
joint (MPJ) region of interest (ROI) (p=0.022) and left heel (p=0.049), as well as a&#xD;
significant difference in mean pressure-time integral under the left 2nd - 4th MPJ ROI&#xD;
(p=0.021) and right heel (p=0.048). There was also a significant difference between Group&#xD;
1 and Group 2 (p=0.044) for left 2nd – 4th MPJ ROI and (p=0.028) right left 2nd – 4th MPJ&#xD;
ROI and between Group 1 and Group 3 (p=0.016) for mean peak plantar pressure of the left&#xD;
2nd – 4th MPJ ROI. No significant difference was found in contact area for both left (p=0.893)&#xD;
and right feet (p=0.800) between the three groups.&#xD;
Conclusion&#xD;
As the duration of diabetes increases, peak plantar pressure increases significantly under the&#xD;
left and right 2nd - 4th metatarsophalangeal joint region of interest. The highest peak plantar&#xD;
pressure at the right 2nd - 4th metatarsophalangeal joint region of interest was 348.93 kPa&#xD;
which is very near to the threshold peak plantar pressures quoted in other research. These&#xD;
findings demonstrate that podiatrists should be encouraged to make more use of pressure&#xD;
mapping technology as part of their clinical treatment plan in patients living with Type 2&#xD;
Diabetes Mellitus without any complications or deformities.
Description: B.SC.(HONS)PODIATRY</summary>
    <dc:date>2017-01-01T00:00:00Z</dc:date>
  </entry>
  <entry>
    <title>The influence of peripheral arterial disease on lower limb surface myoelectric signals in patients living with Type II Diabetes Mellitus</title>
    <link rel="alternate" href="https://www.um.edu.mt/library/oar/handle/123456789/28372" />
    <author>
      <name />
    </author>
    <id>https://www.um.edu.mt/library/oar/handle/123456789/28372</id>
    <updated>2018-06-20T07:41:52Z</updated>
    <published>2017-01-01T00:00:00Z</published>
    <summary type="text">Title: The influence of peripheral arterial disease on lower limb surface myoelectric signals in patients living with Type II Diabetes Mellitus
Abstract: Aim:&#xD;
The aim of this study was to evaluate whether there are any significant differences in muscle&#xD;
activity between individuals living with type II diabetes mellitus (DM) and individuals living&#xD;
with type II DM and peripheral arterial disease (PAD), during gait, at a self-selected speed&#xD;
and at various gait transition speeds. The influence of different stages of PAD on muscle&#xD;
activity during gait was also assessed with the use of surface electromyography.&#xD;
Research Design and Method:&#xD;
A prospective, comparative, non-experimental study was conducted. Ninety participants&#xD;
were divided into three groups namely Group A (thirty participants living with type II DM),&#xD;
Group B(i) (thirty participants living with type II DM and mild PAD) and Group B(ii) (thirty&#xD;
participants living with type II DM and severe PAD). Surface electrode sensors were placed&#xD;
according to SENIAM guidelines, on six lower limb muscles on both limbs, namely, rectus&#xD;
femoris, biceps femoris, tibialis anterior, medial head of gastrocnemius, peroneus longus and&#xD;
extensor hallucis longus. Muscle activity was recorded using a 16-channel Trigno™&#xD;
Wireless System by Delsys®, where participants were instructed to walk at a self-selected&#xD;
speed on a 10-m walkway. This procedure was repeated at 5% and 10% above the step&#xD;
frequency using a digital metronome. The raw data was transferred to Delsys EMGworks®&#xD;
Analysis software to be processed and analysed. Averaged Burst RMS was used to analyse&#xD;
the amplitude (mV) and the duration of muscle activation (s) of each signal.&#xD;
Results:&#xD;
There was a significant increase in muscle amplitude and duration of activation in the&#xD;
presence of lower limb ischaemia during gait at a self-selected speed and at 5% and 10%&#xD;
above the baseline step frequency. The largest significant difference (p = &lt; 0.05) in EMG&#xD;
amplitude and duration of activation when looking at the six muscles in general was found&#xD;
between participants living with Type II DM [Group A] and participants living with Type II&#xD;
DM and severe PAD [Group B(ii)]. No significant difference was found between baseline&#xD;
step frequency, 5% above the baseline step frequency (Speed 2) and 10% above the baseline&#xD;
step frequency (Speed 3) in the mean EMG muscle amplitude and duration of activation in&#xD;
all six muscles tested.&#xD;
Conclusion:&#xD;
The findings in this study show that there was an increase in muscle EMG amplitude and&#xD;
duration of activation in individuals living with PAD during gait. This indicates that there&#xD;
are musculoskeletal and biomechanical changes in the lower limb musculature with&#xD;
increasing severity of PAD. Higher muscle exertion demands are required during gait to&#xD;
produce the desired action which may result in earlier fatigue. Electromyographic tests in&#xD;
the clinical setting would be beneficial for detecting muscle dysfunction objectively and noninvasively,&#xD;
even during early stages of the disease, thus reducing the risk of lower limb&#xD;
complications associated with type II DM and PAD.
Description: M.SC.CLINICAL BIOMECHANICS</summary>
    <dc:date>2017-01-01T00:00:00Z</dc:date>
  </entry>
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