https://www.um.edu.mt/library/oar/handle/123456789/754 2026-09-15T20:40:02Z 2026-09-15T20:40:02Z Suleiman, Sherif Schembri-Wismayer, Pierre Calleja-Agius, Jean https://www.um.edu.mt/library/oar/handle/123456789/149151 2026-09-15T10:45:28Z 2020-01-01T00:00:00Z

Title: The effect of a regeneration extract from the Mexican axolotl on the HL60 leukaemia cell line Authors: Suleiman, Sherif; Schembri-Wismayer, Pierre; Calleja-Agius, Jean Abstract: Even though the mortality rates from malignant cancers have decreased, a lot still needs to be done in terms of improving the overall treatment regimens and eliminate or reduce the “the one size fits all” strategy that is currently the case. Description: A poster presentation is available within this record.

2020-01-01T00:00:00Z Persson, Martin Westergren, Albert Hagell, Peter Jagomägi, Triin Vidya Mehendale, Felicity Radojcic, Julija Calleja-Agius, Jean Sharratt, Nicholas Davies, Gareth Koleventi, Katerina Laustsen, Christine E. https://www.um.edu.mt/library/oar/handle/123456789/149147 2026-09-15T10:33:08Z 2026-01-01T00:00:00Z

Title: Improving equity in cleft lip and/or palate care : findings from a European group concept mapping study Authors: Persson, Martin; Westergren, Albert; Hagell, Peter; Jagomägi, Triin; Vidya Mehendale, Felicity; Radojcic, Julija; Calleja-Agius, Jean; Sharratt, Nicholas; Davies, Gareth; Koleventi, Katerina; Laustsen, Christine E. Abstract: Objective: To identify feasible and high-priority actions to improve the equitable provision of care for individuals with cleft lip and/or palate (CL/P) across Europe.; Design: Participatory mixed-methods study using group concept mapping.; Setting: European cleft and craniofacial care systems.; Patients and Participants: Sixty-five stakeholders from 29 countries, including healthcare professionals, researchers, teachers and representatives from patient organisations involved in CL/P care. Interventions: Participants generated, sorted and rated statements in response to a structured focus prompt addressing equity in CL/P care, with ratings of importance and ease of implementation.; Main Outcome Measure(s): Conceptual clusters of actions to improve equity in CL/P care and prioritisation of actions based on importance and feasibility.; Results: A total of 111 statements were analysed using multi-dimensional scaling and hierarchical cluster analysis, resulting in 6 conceptual clusters: person-centred care; healthcare professional training, awareness and knowledge; resources and availability; inclusiveness and support strategies; European standardisation and governmental health policies. These clusters aligned with micro-, meso- and macro-level domains. Go-Zone analysis identified 31 actions rated as both highly important and feasible, alongside 28 actions rated as highly important but difficult to implement, reflecting longer-term structural and policy challenges.; Conclusions: This study provides an empirically grounded, multi-level roadmap for advancing equitable and high-quality CL/P care across Europe. While immediate improvements can be achieved through targeted clinical and organisational actions, sustained progress requires coordinated policy and governance reform. The identified principles may provide insights for cleft care service providers beyond Europe who face similar systemic challenges.

2026-01-01T00:00:00Z Calleja-Agius, Jean Muttukrishna, Shanthi Jauniaux, Eric R. M. https://www.um.edu.mt/library/oar/handle/123456789/149116 2026-09-15T08:53:11Z 2011-01-01T00:00:00Z

Title: The effect of coelomic fluid on the production of interleukin-10, tumor necrosis factor-α and receptors by the first trimester human placenta Authors: Calleja-Agius, Jean; Muttukrishna, Shanthi; Jauniaux, Eric R. M. Abstract: Context: The exocoelomic cavity plays an important role as a fetal biological reservoir and materno-fetal exchange interface during the fi rst trimester of human pregnancy.; Objective: We investigated the effect of coelomic fl uid on total production of cytokines and their receptors in normal fi rst trimester human placenta cultured at different concentrations of oxygen.

2011-01-01T00:00:00Z Calleja-Agius, Jean Jauniaux, Eric R.M. Muttukrishna, Shanthi https://www.um.edu.mt/library/oar/handle/123456789/149115 2026-09-15T08:45:17Z 2014-01-01T00:00:00Z

Title: Inflammatory cytokines in the placenta and maternal circulation of chromosomally abnormal first trimester miscarriages Authors: Calleja-Agius, Jean; Jauniaux, Eric R.M.; Muttukrishna, Shanthi Abstract: Study question: The impact of abnormal placental karyotype on the inflammatory response within the villous tissue and peripheral circulation of women with miscarriage was evaluated.; Summary answer: In miscarriage with abnormal karyotype, there is an exacerbated placental inflammatory response, in contrast to miscarriage of normal karyotype where maternal systemic response is increased.

2014-01-01T00:00:00Z