OAR@UM Collection:
https://www.um.edu.mt/library/oar/handle/123456789/12459
2024-03-29T08:50:39ZThe Synapse : the medical professionals' network : volume 13 : issue 4
https://www.um.edu.mt/library/oar/handle/123456789/13971
Title: The Synapse : the medical professionals' network : volume 13 : issue 4
Editors: Galea, Wilfred; Ellul, Ian C.
Abstract: Apart from the normal articles regarding medicine, this issue contains also the following: “A chance for Maltese medical students
to make their voice heard” - Rebecca Stoner (MMSA); From the pitch to the pharmacy (Josie Cachia) - Marika Azzopardi2014-01-01T00:00:00ZInflammation and insulin resistance : evolution, pathology and therapy
https://www.um.edu.mt/library/oar/handle/123456789/13969
Title: Inflammation and insulin resistance : evolution, pathology and therapy
Authors: Pace, Nikolai Paul
Abstract: Chronic low-level subclinical inflammation is an established
risk factor in the development of insulin resistance, endothelial
damage and atherosclerosis. The obesity-associated insulin
resistance in adipose, liver and muscle tissue is promoted by a
switch in macrophage activation driven by transcription factors
that play crucial roles in innate immunity. This review discusses
the evolutionary link between body defense mechanisms and
insulin resistance.2014-01-01T00:00:00ZUltra sound-guided thyroid fine needle aspiration
https://www.um.edu.mt/library/oar/handle/123456789/13968
Title: Ultra sound-guided thyroid fine needle aspiration
Authors: Vassallo, Pierre
Abstract: Fine Needle Aspiration (FNA) is a minimally invasive method for sampling focal lesions
that uses a small gauge hypodermic needle (20-24 Gauge) to obtain cells for microscopic
analysis. This is in contrast to core biopsy which obtains a core of tissue using larger
gauge cutting needles (14-18 Gauge). Both FNA and core biopsies are classified as closed
or percutaneous biopsies as opposed to open biopsy that is obtained during surgery.
Ultrasound (US)-guided FNA lends itself particularly well to
lesions in superficial organs such as the thyroid, lymph nodes
and the breast. However, since it is less traumatic than core
biopsy, it is safer for use in highly vascular organs such as the
thyroid gland. Smaller nodules are more amnable to FNA, while
larger nodules are better sampled with core biopsy.2014-01-01T00:00:00ZOncogene addiction might be the Achilles heel in cancer : part 2
https://www.um.edu.mt/library/oar/handle/123456789/13958
Title: Oncogene addiction might be the Achilles heel in cancer : part 2
Authors: Grech, Alfred; Baldacchino, Alexandra
Abstract: Part 2 of the article.
Multiple and complex genetic and epigenetic abnormalities underlie the multistage transformation of normal cells into cancerous ones. Among these abnormalities are the activation of oncogenes and loss of function of tumour suppressor genes. Besides these abnormalities, it is becoming evident that specific cancers are dependent on one or a few genes for their malignant phenotype, and this could be their ‘Achilles heel’. This survival dependency of cancer cells on an activated oncogene or inactivation of tumour suppressor gene is called ‘oncogene addiction’ and may well be a potential way to provide more rational molecular targeted therapy
Description: Part 1 of the article is found through this link :
https://www.um.edu.mt/library/oar//handle/123456789/139622014-01-01T00:00:00Z