https://www.um.edu.mt/library/oar/handle/123456789/34657 2026-04-11T11:26:31Z https://www.um.edu.mt/library/oar/handle/123456789/13828 Title: Polycystic ovary syndrome Authors: Vassallo, Josanne; Craus, Sara Abstract: Polycystic ovary syndrome (PCOS), previously referred to as Stein-Leventhal syndrome, is a worldwide disorder affecting about one fifth of women in their reproductive years. It causes disturbances in reproductive, endocrine and metabolic functions. PCOS is the focus of a great deal of research and studies indicate that its prevalence is on the increase. The main characteristics of PCOS are ovulatory dysfunction, hyperandrogenism, insulin resistance and obesity but one need to investigate and exclude other functional disorders which may resemble PCOS. A key feature of the PCOS is an increased level of luteinizing hormone (LH) which may prevent the maturation of the ovum when it completes the first meiotic division and may thus be responsible for causing infertility in some women 2014-01-01T00:00:00Z https://www.um.edu.mt/library/oar/handle/123456789/13827 Title: Is there a role for genetic risk prediction studies in type 2 diabetes? Authors: Pace, Nikolai Paul Abstract: Type 2 diabetes develops from the interaction between non-genetic (environmental/lifestyle) and genetic factors. One of the challenges of personalized genomics is the prediction of disease risk. This review examines the challenges of risk prediction studies and the barriers to their implementation in the clinic 2014-01-01T00:00:00Z https://www.um.edu.mt/library/oar/handle/123456789/13826 Title: Pharma's kryptonite Authors: Ellul, Ian C. Abstract: Editorial regarding the pharmaceutical industry. 2014 will herald existing and new challenges for the pharmaceutical industry. Diminishing pipelines, increasing development costs, generic competition... pharmaceutical companies are under constant pressure to innovate and collaborate if they want to survive. As a point of fact, over 700 biotechnology and pharma takeovers have occurred in the past four years 2014-01-01T00:00:00Z https://www.um.edu.mt/library/oar/handle/123456789/13823 Title: Bacterial conjunctivitis Authors: Gouder, Melvin J. Abstract: Bacterial conjunctivitis is a very common ophthalmic condition that can affect anyone from day one of life to old age. It is one of the commonest reasons for self-referrals of patients visiting eye specialists. It is defined ad an inflammation of the conjunctiva by bacteria where the palpebral, bulbar and forniceal parts of the conjunctiva become hyperaemic. The infection can be acute, hyperacute or chronic. Contrary to popular belief it can be self-limiting but it is frequently treated with broad-spectrum antibiotics most commonly in drop form. Very rarely it can progress to complications such as keratitis (corneal infection) or pre-septal cellulitis (skin infection of the lids) 2014-01-01T00:00:00Z