https://www.um.edu.mt/library/oar/handle/123456789/3597 2026-04-08T16:40:11Z https://www.um.edu.mt/library/oar/handle/123456789/3876 Title: Diagnosis and management of pulmonary arteriovenous malformations Authors: Papagiannis, John; Apostolopoulou, Sotiria C.; Rammos, Spyridon; Sarris, G.E. Abstract: Pulmonary arteriovenous malformation is a rare anomaly that presents in several different ways. It can present as an isolated finding, or more often in the context of hereditary haemorrhagic telangiectasia. It can also complicate palliative surgery such as the Glenn operation for complex congenital heart disease with single ventricle physiology. Its management includes transcatheter embolization, which is the preferred mode of therapy, surgery (including resection of the affected lobe, segment, or the fistula itself), or rarely, medical therapy. Complications of the disease itself and of various modes of treatment are relatively common, and patients require close surveillance for possible recurrence, or development of new fistulas. In cases related to the Glenn operation, redirection of hepatic venous flow or heart transplantation may cure the problem. 2002-01-01T00:00:00Z https://www.um.edu.mt/library/oar/handle/123456789/3860 Title: Ethical issues in paediatric practice : part II : issues relating to disability Authors: Attard-Montalto, Simon Abstract: Ethical issues in child care are often complicated by the child's inability to take responsibility in their own management decisions and, therefore, their reliance on third parties. This situation is further complicated in those children who have an underlying disability which may influence judgement decisions of the child's surrogate guardians, both toward over or under treatment. This is particularly the case with regard to decisions relating to life support, ongoing and quality of life, appropriate use of limited healthcare resources, and medical research. This article will explore the ethical principles which help to guide the medical management of such difficult cases. 2002-01-01T00:00:00Z https://www.um.edu.mt/library/oar/handle/123456789/3857 Title: The legitimacy and advantages of electronic publication Abstract: This article discusses the diverse challenges that online publication has created for academic institutions, authors, journal editorial boards, publishers, libraries and readers. 2002-01-01T00:00:00Z https://www.um.edu.mt/library/oar/handle/123456789/3856 Title: Inhaled nitric oxide applications in paediatric practice Authors: Bernasconi, A.; Beghetti, Maurice Abstract: The nitric oxide pathway plays a pivotal, yet diverse, role in human physiology, including modulation of vascular tone, neural transmission and inflammation. Inhaled nitric oxide is a selective pulmonary vasodilator that has emerged rapidly as an important therapeutic agent. It finds its best applications in paediatrics; the use of iNO in term neonates with hypoxaemic respiratory failure, in the assessment of pulmonary vascular reactivity and in the treatment of postoperative pulmonary hypertension in congenital heart disease is well recognised and accepted. This review details the delivery and monitoring aspects of inhaled nitric oxide, its potential toxic and side effects and its applications in several cardiopulmonary disorders in paediatrics. 2002-01-01T00:00:00Z