https://www.um.edu.mt/library/oar/handle/123456789/34587 Mon, 06 Apr 2026 07:16:56 GMT 2026-04-06T07:16:56Z https://www.um.edu.mt/library/oar/handle/123456789/13161 Title: IgG4-related autoimmune disease : imaging findings Authors: Vassallo, Pierre Abstract: IgG4 autoimmune disease (or hyper IgG4 disease) is a relatively recently described systemic disease that is characterised by abundant infiltration of IgG4-positive plasma cells and lymphocytes with associated fibrosis leading to organ dysfunction. Tue, 01 Jan 2013 00:00:00 GMT https://www.um.edu.mt/library/oar/handle/123456789/13161 2013-01-01T00:00:00Z https://www.um.edu.mt/library/oar/handle/123456789/13134 Title: The Synapse : the medical professionals' network Editors: Galea, Wilfred; Ellul, Ian C. Abstract: Apart from the normal articles regarding medicine, this issue contains also the following: Postgraduate education for healthcare professionals - Janet Sultana; Successful business lunches - Massimo Azzopardi; The singing medicine man (Gianluca Bezzina) - Marika Azzopardi Tue, 01 Jan 2013 00:00:00 GMT https://www.um.edu.mt/library/oar/handle/123456789/13134 2013-01-01T00:00:00Z https://www.um.edu.mt/library/oar/handle/123456789/13132 Title: HERVs, transposons and human diseases : part 3 Authors: Grech, Alfred; Baldacchino, Sandra Abstract: Part 3 of the article. It has been found that the human genome is full of relic retroviral DNA sequences called HERVs (Human Endogenous RetroViruses). A HERV is a type of a transposon, the latter being a piece of DNA sequence that can move from one position to another position in the genome, hence its other name of ‘jumping gene’. HERVs and other transposons are held in check from doing havoc in the genome by several mechanisms, one of which is epigenetic in nature (namely DNA methylation and histone modifications). HERVs and other transposons are being implicated to have physiological and pathological functions in the genomes of the cells that host them. Accumulating evidence is showing that they may be associated with certain human diseases, specifically in some autoimmune diseases (e.g. rheumatoid arthritis, psoriasis, systemic lupus erythematosus, insulin-dependent diabetes mellitus), neurological diseases (e.g. schizophrenia, multiple sclerosis, motor neuron disease) and cancer. Understanding how these relic viruses and other jumping genes bring about these human diseases could help in their prevention and treatment. Description: Part 1 and 2 of this article can be found through theses links: https://www.um.edu.mt/library/oar//handle/123456789/12961 https://www.um.edu.mt/library/oar//handle/123456789/13012 Tue, 01 Jan 2013 00:00:00 GMT https://www.um.edu.mt/library/oar/handle/123456789/13132 2013-01-01T00:00:00Z https://www.um.edu.mt/library/oar/handle/123456789/13131 Title: Epidemiology of mixed vaginitis and its management Authors: Galea, Therese Abstract: Vaginitis is a common reason for visits to a health care provider, accounting for 6 million visits per year. Symptoms associated with vaginitis can cause substantial distress, resulting in time lost from work and altered self-esteem. It is estimated that over a billion dollars is spent annually on both self-treatment and visits to a medical provider. Tue, 01 Jan 2013 00:00:00 GMT https://www.um.edu.mt/library/oar/handle/123456789/13131 2013-01-01T00:00:00Z