https://www.um.edu.mt/library/oar/handle/123456789/72983 Tue, 05 May 2026 22:10:54 GMT 2026-05-05T22:10:54Z https://www.um.edu.mt/library/oar/handle/123456789/72834 Title: Cancer epigenetics and its clinical applications Authors: Grech, Alfred; Balzan, Michael Abstract: Epigenetics is defined as 'somatically inheritable changes that are not accompanied by alterations in DNA sequence'. DNA methylation, histone modifications and non-coding RNAs are all epigenetic mechanisms. Epigenetic aberrations (or epimutations) have been found to be responsible for carcinogenesis. The research of these epimutations is providing a platform for their application in cancer diagnosis, prognosis and therapeutics. Wed, 01 Jan 2020 00:00:00 GMT https://www.um.edu.mt/library/oar/handle/123456789/72834 2020-01-01T00:00:00Z https://www.um.edu.mt/library/oar/handle/123456789/72833 Title: Getting to grips with SPMS Abstract: DR JOSANNE AQUILINA discusses the management of Secondary Progressive Multiple Sclerosis with DR IAN ELLUL. Wed, 01 Jan 2020 00:00:00 GMT https://www.um.edu.mt/library/oar/handle/123456789/72833 2020-01-01T00:00:00Z https://www.um.edu.mt/library/oar/handle/123456789/72830 Title: The Synapse : the Medical Professionals' Network : volume 19 : issue 5 Editors: Galea, Wilfred; Ellul, Ian C. Abstract: Table of contents:; 1/ ELLUL, I. C. - Vaccination : quo vadis?; 2/ ELLUL, I. C., AQUILINA, J. - Getting to grips with SPMS; 3/ CILIA-VINCENTI, A. - Can bronchial carcinoma be ascribed to asbestos exposure for industrial disease compensation purposes?; 4/ GRECH, A., & BALZAN, M. - Cancer epigenetics and its clinical applications; 5/ CAUCHI, M. - Doctors for the Environment Malta; 6/ CAMILLERI, M. - Smoking in the 21st century; 7/ FALZON, S., COLLICT, M., & SALIBA, I. - Cervical cancer : the importance of screening and vaccination; 8/ VASSALLO, P. - Imaging back pain : part 2 Wed, 01 Jan 2020 00:00:00 GMT https://www.um.edu.mt/library/oar/handle/123456789/72830 2020-01-01T00:00:00Z https://www.um.edu.mt/library/oar/handle/123456789/72829 Title: Vaccination : quo vadis? Abstract: Evidence has it that the multi-organ effect of Sars-CoV-2 is primarily attributed to hypercytokinemia, especially in the elderly & immunocompromised. Malta has suffered the brunt of this. According to the European Centre for Disease Prevention and Control, as of 30 September 2020, the 14-day cumulative number of Covid-19 deaths per 100,000 was 3.6 for Malta, topping the EU/EEA charts. If Covid-19 excess deaths were factored in, Malta would possibly fare better; nonetheless Malta is facing a serious problem stemming from the ingrained laissez-faire attitude of the general public. [excerpt] Wed, 01 Jan 2020 00:00:00 GMT https://www.um.edu.mt/library/oar/handle/123456789/72829 2020-01-01T00:00:00Z