Please use this identifier to cite or link to this item:
https://www.um.edu.mt/library/oar/handle/123456789/136617| Title: | Expression of cell cycle regulators and biomarkers of proliferation and regrowth in human pituitary adenomas |
| Authors: | Gruppetta, Mark Formosa, Robert Falzon, Sharon Ariff Scicluna, Sabrina Falzon, Edward DeGaetano, James Vassallo, Josanne |
| Keywords: | Pituitary gland -- Tumors Somatostatin Carcinogenesis Regeneration (Biology) |
| Issue Date: | 2018 |
| Publisher: | University of Malta. Medical School |
| Citation: | Gruppetta, M., Formosa, R., Falzon, S., Ariff Scicluna, S., Falzon, E., DeGaetano, J., & Vassallo, J. (2018). Expression of cell cycle regulators and biomarkers of proliferation and regrowth in human pituitary adenomas. Malta Medical Journal, 30(S), 49-50. |
| Abstract: | Introduction: The pathogenesis of pituitary adenomas
(PA) is complex. Ki-67, pituitary tumour transforming gene
(PTTG), vascular endothelial growth factor (VEGF), cyclin
D1, c-MYC and pituitary adenylate cyclase-activating peptide (PACAP) protein expression were analysed and
correlated with tumour and patient characteristics. Methods: A total of 74 pituitary tumour samples (48 nonfunctional PA, 26 functional PA); Immunohistochemical analysis of protein expression, retrospective analysis of MR images and in vitro analysis of octreotide treatment was carried out on GH3 cells. |
| URI: | https://www.um.edu.mt/library/oar/handle/123456789/136617 |
| ISSN: | 18133339 |
| Appears in Collections: | Scholarly Works - FacM&SMed |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Expression of cell cycle regulators and biomarkers of proliferation and regrowth in human pituitary adenomas 2018.pdf | 130.17 kB | Adobe PDF | View/Open |
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