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Full metadata record
DC Field | Value | Language |
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dc.contributor.author | Grech, Alfred | - |
dc.contributor.author | Balzan, Michael | - |
dc.date.accessioned | 2016-11-24T10:07:54Z | - |
dc.date.available | 2016-11-24T10:07:54Z | - |
dc.date.issued | 2016 | - |
dc.identifier.citation | Grech, A. & Balzan, M. (2016). The dark matter of the genome : some insights and clinical applications. The Synapse, 15(3), 7-9 | en_GB |
dc.identifier.uri | https://www.um.edu.mt/library/oar//handle/123456789/14272 | - |
dc.description.abstract | Only approximately 1.5% of the human genome encodes protein sequence; the rest is ‘dark matter’. Research on these noncoding regions shows that they play roles in cellular homeostasis, development, differentiation and metabolism. Cancer, cardiovascular, developmental, and neurological diseases are characterised by aberrant expression of these regions. Exploring their clinical utility as biomarkers and molecular targets in medical theranostics is a very promising way forward. | en_GB |
dc.language.iso | en | en_GB |
dc.publisher | Medical Portals Ltd. | en_GB |
dc.rights | info:eu-repo/semantics/openAccess | en_GB |
dc.subject | Human genome | en_GB |
dc.subject | Genomics | en_GB |
dc.subject | RNA | en_GB |
dc.title | The dark matter of the genome : some insights and clinical applications | en_GB |
dc.type | article | en_GB |
dc.rights.holder | The copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder. | en_GB |
dc.description.reviewed | peer-reviewed | en_GB |
Appears in Collections: | The Synapse, Volume 15, Issue 3 The Synapse, Volume 15, Issue 3 |
Files in This Item:
File | Description | Size | Format | |
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The dark matter of the genome.pdf | 2.33 MB | Adobe PDF | View/Open |
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