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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Navailles, Sylvia | - |
| dc.contributor.author | Di Giovanni, Giuseppe | - |
| dc.contributor.author | De Deurwaerdère, Philippe | - |
| dc.date.accessioned | 2017-10-13T16:19:37Z | - |
| dc.date.available | 2017-10-13T16:19:37Z | - |
| dc.date.issued | 2014 | - |
| dc.identifier.citation | Navailles, S., Di Giovanni, G., & De Deurwaerdère, P. (2014). Predicting dopaminergic effects of L-DOPA in the treatment for Parkinson's disease. CNS Neuroscience & Therapeutics, 20(7), 699-701. | en_GB |
| dc.identifier.uri | https://www.um.edu.mt/library/oar//handle/123456789/22584 | - |
| dc.description.abstract | Numerous advances have been made in the understanding of the mechanism of action of the antiparkinsonian medicine L-DOPA. This has allowed for the development of interesting predictive models regarding the positive and side effects of this medication. Recently, a mathematical model has been developed to investigate the impact of L-DOPA on dopamine (DA) release from serotonergic (5-HT) terminals in the striatum. The parameters used to elaborate this model were partially based on experimental data and may not be sufficient to illustrate the biochemical effects of L-DOPA inside 5-HT terminals. | en_GB |
| dc.language.iso | en | en_GB |
| dc.publisher | Wiley-Blackwell Publishing Ltd. | en_GB |
| dc.rights | info:eu-repo/semantics/restrictedAccess | en_GB |
| dc.subject | Parkinson's disease -- Treatment | en_GB |
| dc.subject | Levodopa | en_GB |
| dc.title | Predicting dopaminergic effects of L-DOPA in the treatment for Parkinson's disease | en_GB |
| dc.type | article | en_GB |
| dc.rights.holder | The copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder. | en_GB |
| dc.description.reviewed | peer-reviewed | en_GB |
| dc.identifier.doi | 10.1111/cns.12252 | - |
| dc.publication.title | CNS Neuroscience & Therapeutics | en_GB |
| Appears in Collections: | Scholarly Works - FacM&SPB | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Navailles et al 2014.pdf Restricted Access | 82.56 kB | Adobe PDF | View/Open Request a copy |
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