Please use this identifier to cite or link to this item:
https://www.um.edu.mt/library/oar/handle/123456789/22778
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Di Giovanni, Giuseppe | - |
dc.contributor.author | Di Matteo, Vincenzo | - |
dc.contributor.author | Esposito, Ennio | - |
dc.date.accessioned | 2017-10-17T13:27:46Z | - |
dc.date.available | 2017-10-17T13:27:46Z | - |
dc.date.issued | 2002 | - |
dc.identifier.citation | Di Giovanni, G., Di Matteo, V., & Esposito, E. (2002). Serotonin/dopamine interaction - focus on 5-HT2C receptor, a new target of psychotropic drugs. Indian Journal of Experimental Biology, 40, 1344-1352. | en_GB |
dc.identifier.uri | https://www.um.edu.mt/library/oar//handle/123456789/22778 | - |
dc.description.abstract | Several hypotheses regarding physiopathology of major psychiatric diseases exist. Attention has been focused on cerebral monoaminergic systems, the dysfunction of which is thought to underlie various aspects of their symptomatology. There are reports describing the involvement of serotonergic and dopaminergic systems in the mechanism of action of psychotropic drugs. This article reviews current knowledge on interaction between 5-hydroxytryptamine (5-HT), acting at 5-HT2C receptors in the central dopamine (DA) systems. Since 90s, a growing body of behavioural, neurochemical and electrophysiological evidence from animal studies have demonstrated a clear role for 5-HT2C receptors in modulation of activity of dopamine neurones. This evidence has led to the suggestion that drugs acting on 5-HT2C receptors have potential as novel antipsychotic and antidepressant agents and may also be used in the treatment of other neuropsychiatric disorders such as Parkinson's disease and psychoactive substance abuse. | en_GB |
dc.language.iso | en | en_GB |
dc.publisher | National Institute of Science Communication and Information Resources | en_GB |
dc.rights | info:eu-repo/semantics/restrictedAccess | en_GB |
dc.subject | Serotonin | en_GB |
dc.subject | Dopamine | en_GB |
dc.subject | Receptor, Serotonin, 5-HT2C | en_GB |
dc.title | Serotonin/dopamine interaction - focus on 5-HT2C receptor, a new target of psychotropic drugs | en_GB |
dc.type | article | en_GB |
dc.rights.holder | The copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder. | en_GB |
dc.description.reviewed | peer-reviewed | en_GB |
dc.publication.title | Indian Journal of Experimental Biology | en_GB |
Appears in Collections: | Scholarly Works - FacM&SPB |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
IJEB 40(12) 1344-1352.pdf Restricted Access | 1.92 MB | Adobe PDF | View/Open Request a copy |
Items in OAR@UM are protected by copyright, with all rights reserved, unless otherwise indicated.