Please use this identifier to cite or link to this item:
Title: Early dialysis in acute kidney injury after cardiac surgery
Authors: Manche, Alexander
Casha, Aaron
Rychter, Jacek
Farrugia, Emanuel
Debono, Miriam
Keywords: Heart -- Surgery
Acute kidney injury
Issue Date: 2008
Publisher: Oxford University Press
Citation: Manche, A., Casha, A. R., Rychter, J., Farrugia, E., & Debono, M. (2008). Early dialysis in acute kidney injury after cardiac surgery. Interactive CardioVascular and Thoracic Surgery, 7(5), 829-832.
Abstract: Acute kidney injury following cardiac surgery (AKICS) remains a frequent cause of major morbidity and mortality. The aim of this study was to examine the influence of timing of dialysis. A retrospective analysis of 3528 patients undergoing cardiac surgery between April 1995 and July 2006 was performed. In group 1 (April 1995–January 2000) intermittent haemodialysis was resorted to when other supportive measures failed. In group 2 (January 2000–July 2006) intermittent haemodialysis was commenced immediately when oliguria did not respond to fluid replacement or single-dose diuretics. In group 1, 49/1511 (3.2%) patients developed AKICS. Thirty-four patients did not receive dialysis and six patients died (18%). Of the remaining 15 patients who underwent dialysis, 13 died (87%). The overall mortality for group 1 AKICS patients was 19/49 (39%). In group 2, 87/2017 (4.3%) patients developed AKICS. Thirty-one patients did not require dialysis and none died. Of the 56 patients who were dialysed, 14 died (25%). During January 2005–July 2006, mortality following dialysis fell further to 17% (4/24). The overall mortality for group 2 patients developing AKICS was 14/87 (16%). Although the incidence of AKICS increased from 3.2% to 4.2%, earlier dialysis resulted in significantly improved survival (P=0.00001).
Appears in Collections:Scholarly Works - FacM&SAna

Files in This Item:
File Description SizeFormat 
Early_dialysis_in_acute_kidney_injury_after_cardi_acsurgery_2008.pdf247.62 kBAdobe PDFView/Open

Items in OAR@UM are protected by copyright, with all rights reserved, unless otherwise indicated.