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Title: The role of genetic susceptibility in diabetic nephropathy : evidence from family studies
Authors: Fava, Stephen
Hattersley, Andrew T.
Keywords: Diabetes -- Malta
Diabetes -- Genetic aspects
Diabetes -- Complications
Diabetic nephropathies
Issue Date: 2002
Publisher: Oxford Academic
Citation: Fava, S., & Hattersley, A. T. (2002). The role of genetic susceptibility in diabetic nephropathy: evidence from family studies. Nephrology Dialysis Transplantation, 17(9), 1543-1546.
Abstract: Diabetic nephropathy is one of the long-term complications of both type 1 and type 2 diabetes. It is a leading cause of end-renal disease in many countries [1]. Furthermore, it is associated with increased cardiovascular mortality, with most of the excess mortality associated with diabetes being seen in those with nephropathy [2,3]. It is impossible to predict which diabetic patients will develop renal disease. Although duration of diabetes, tightness of glycaemic control, and blood pressure are undoubtedly implicated [4,5], these factors are insufficient on their own to predict which patients will develop the complication. Therefore, a patient with poor blood pressure and glycaemic control might not develop diabetic renal disease even many years after diagnosis of diabetes. Clearly, other factors must also be involved.
Appears in Collections:Scholarly Works - FacM&SMed

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