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Title: Heart disease in thalassemia heterozygotes with sickle cell anemia
Authors: Covitz, Wesley
Felice, Alex
Milner, Paul F.
McKie, Virgil C.
McKie, Kathleen Mood
Strong, William B.
Davis, Harry C.
Keywords: Heart -- Diseases
Sickle cell anemia
Issue Date: 1987
Publisher: Nature Publishing Group
Citation: Covitz, W., Felice, A. E., Milner, P. F., McKie, V. C., McKie, K. M., Strong, W. B., & Davis, H. C. (1987). Heart disease In thalassemia heterozygotes with sickle cell anemia. Pediatric Research, 21(4), 188A.
Abstract: The purpose of this study was to ascertain whether thalassemia heterozygotes (α thal) who have sickle cell anemia (SCA) suffer fewer cardiac effects of their SCA due to an increased oxygen carrying capacity or decreased sickling. Echocardiograms and graded, maximal exercise tests were performed in 22 subjects withα thal and SCA, and in 22 age and sex matched controls (C) with SCA alone. The patients ranged in age from 8-32 years.
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