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Please use this identifier to cite or link to this item: https://www.um.edu.mt/library/oar/handle/123456789/32227
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dc.contributor.authorBosica, Giovanna-
dc.contributor.authorZammit, Ramon-
dc.date.accessioned2018-07-25T06:00:22Z-
dc.date.available2018-07-25T06:00:22Z-
dc.date.issued2018-
dc.identifier.citationBosica, G., & Zammit, R. (2018). One-pot multicomponent nitro-Mannich reaction using a heterogeneous catalyst under solvent-free conditions. PeerJ, 6(e5065), 1-29.en_GB
dc.identifier.urihttps://www.um.edu.mt/library/oar//handle/123456789/32227-
dc.description.abstractAn environmentally-friendly, one-pot multicomponent reaction of various aldehydes, amines and nitroalkanes for the synthesis of β-nitroamines is here described. Amberlyst A-21 supported CuI was found to be a highly efficient novel heterogeneous catalyst for the three-component nitro-Mannich reaction between aldehydes, amines and nitroalkanes. The developed protocol is performed in a solvent-free medium to produce a variety of β-nitroamines in good to excellent yields within short reaction times. The catalyst can be easily prepared and recovered. It has been tested up to eight times with only a minor activity loss.en_GB
dc.language.isoenen_GB
dc.publisherPeerJ Inc.en_GB
dc.rightsinfo:eu-repo/semantics/openAccessen_GB
dc.subjectHeterogeneous catalysisen_GB
dc.subjectSolventsen_GB
dc.subjectAsymmetric synthesisen_GB
dc.subjectAldehydesen_GB
dc.subjectNitroalkanesen_GB
dc.subjectChemistry, Organicen_GB
dc.titleOne-pot multicomponent nitro-Mannich reaction using a heterogeneous catalyst under solvent-free conditionsen_GB
dc.typearticleen_GB
dc.rights.holderThe copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holderen_GB
dc.description.reviewedpeer-revieweden_GB
dc.identifier.doi10.7717/peerj.5065-
dc.publication.titlePeerJen_GB
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