Please use this identifier to cite or link to this item:
Full metadata record
DC FieldValueLanguage
dc.contributor.authorScerri, Charles-
dc.identifier.citationScerri, C. (2008). Neural stem cells and the aging brain : part 2. The Synapse : the Medical Professionals' Network, 2, 8-10.en_GB
dc.description.abstractNeural stem cells have a number of potential applications in treating neurodegenerative disorders. Neurons lost duri~g the disease process may be replaced either by facilitating the proliferation of neural stem cells already present in the brain (endogenous replacement) or else by transplantation of neural stem cells in the damaged area of the brain (exogenous replacement). For transplantation to be viable, cells have to fulfill three important criteria. Firstly, the transplanted cells must survive the procedure. Secondly, the transplanted neural stem cell has to develop in the required type of brain cell and finally, the transplanted cell must make the necessary connections to survive and be part of the existent neural network. If transplantation occurs in a diseased brain, the newly transplanted cell must also survive in the dis eased environment. Although recent studies using animal models showed promising results, exogenous transplantation of neural stem cells is still a long way to go. One of the major limitations is that it is still difficult to produce the type of replacement cell needed following differentiation in vivo.en_GB
dc.publisherMedical Portals Ltd.en_GB
dc.subjectNeural stem cells -- Transplantationen_GB
dc.subjectNeural stem cells -- Regenerationen_GB
dc.subjectBrain -- Agingen_GB
dc.subjectNervous system -- Diseases -- Treatmenten_GB
dc.titleNeural stem cells and the aging brain : part 2en_GB
dc.rights.holderThe copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder.en_GB
dc.publication.titleThe Synapse : the Medical Professionals' Networken_GB
Appears in Collections:The Synapse, Issue 02/08
The Synapse, Issue 02/08

Files in This Item:
File Description SizeFormat 
The_Synapse,_2-08_-_A4.pdf1.58 MBAdobe PDFView/Open

Items in OAR@UM are protected by copyright, with all rights reserved, unless otherwise indicated.