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DC Field | Value | Language |
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dc.contributor.author | Xuereb, Sarah | - |
dc.contributor.author | Pavia, Jessica | - |
dc.contributor.author | Brincat, Mark R. | - |
dc.contributor.author | Tanti, Charmaine | - |
dc.contributor.author | Saliba, Isabelle | - |
dc.date.accessioned | 2020-01-09T12:53:22Z | - |
dc.date.available | 2020-01-09T12:53:22Z | - |
dc.date.issued | 2019-12 | - |
dc.identifier.citation | Xuereb, S., Pavia, J., Brincat, M. R., Tanti, C., & Saliba, I. (2019). Assessing the see-and-treat approach for the management of high-grade squamous intraepithelial cervical lesions. Malta Medical Journal, 8(2), 2-7. | en_GB |
dc.identifier.uri | https://www.um.edu.mt/library/oar/handle/123456789/50258 | - |
dc.description.abstract | Objectives: To assess local histological outcomes in patients with HSIL cytology results on cervical smears, in both the see-and-treat and three-step approach. Study Design: A retrospective analysis of patients with HSIL on cervical cytology was performed, obtaining an 83 patient cohort. The histological result following the primary investigation (colposcopic-directed biopsy or excisional procedure) was noted for each patient together with their demographic variables and HPV status. Results: Of 83 patients with HSIL cytology on cervical smear, 43 underwent LLETZ as a primary procedure, while 40 patients underwent a colposcopic-directed biopsy. There was no statistically significant difference in terms of dermographics and HPV status between the two groups. In those patients who had LLETZ as a primary procedure, 29 had CIN2+ on histology. On the other hand, following colposcopic-directed biopsies, 17 resulted in CIN2+ on histology. Conclusion: The conventional approach within our local setting potentially has inferior sensitivity in picking up CIN2+ lesions when compared to the see-and-treat approach. On the other hand, primary excisional procedures were associated with an overtreatment rate of at least 20.9%, subjecting patients to unnecessary risks. Local improvement of colposcopic skill will aid to reduce this overtreatment rate and missed lesions at biopsy. | en_GB |
dc.language.iso | en | en_GB |
dc.publisher | University of Malta. Medical School | en_GB |
dc.rights | info:eu-repo/semantics/openAccess | en_GB |
dc.subject | Colposcopy | en_GB |
dc.subject | Cervix uteri -- Cancer -- Diagnosis | en_GB |
dc.subject | Cervix uteri -- Cancer -- Treatment | en_GB |
dc.subject | Medical overuse | en_GB |
dc.title | Assessing the see-and-treat approach for the management of high-grade squamous intraepithelial cervical lesions | en_GB |
dc.type | article | en_GB |
dc.rights.holder | The copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder. | en_GB |
dc.description.reviewed | peer-reviewed | en_GB |
dc.publication.title | Malta Medical Journal | en_GB |
Appears in Collections: | MMJ, Volume 31, Issue 3 MMJ, Volume 31, Issue 3 Scholarly Works - FacM&SOG |
Files in This Item:
File | Description | Size | Format | |
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MMJ31(3)A1.pdf | 1.2 MB | Adobe PDF | View/Open |
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