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DC Field | Value | Language |
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dc.date.accessioned | 2020-04-14T08:44:53Z | - |
dc.date.available | 2020-04-14T08:44:53Z | - |
dc.date.issued | n.d. | - |
dc.identifier.citation | Vella, J., Zammit, C., Zammit, R., Borg, D., & Valentino, M. (n. d.). L-lactate reduces ischemia-induced oligodendrocyte injury and modulates white matter HCA1 expression in a mouse MCAO model. Laboratory for the Study of Neurological Disorders | en_GB |
dc.identifier.uri | https://www.um.edu.mt/library/oar/handle/123456789/54151 | - |
dc.description.abstract | Stroke is a leading cause of death and long-term disability. In ischemic stroke, arterial occlusion interrupts cerebral blood flow and substrate delivery to brain tissue, resulting in multicellular death due to energy failure. An ischemic core of necrotic cell death immediate to the occluded artery is surrounded by a peri-infarct penumbra where energy metabolism is preserved due to a less severe blood flow reduction. White cells within the ischemic core are irreversibly injured, tissue within the penumbra may be salvaged by timely recanalization, making the penumbra the target for several neuroprotective therapies. | en_GB |
dc.language.iso | en | en_GB |
dc.publisher | Laboratory for the Study of Neurological Disorders | en_GB |
dc.rights | info:eu-repo/semantics/openAccess | en_GB |
dc.subject | Transient ischemic attack | en_GB |
dc.subject | White matter | en_GB |
dc.subject | Oligodendroglia | en_GB |
dc.subject | Glucose -- Metabolism | en_GB |
dc.subject | Metabolic syndrome | en_GB |
dc.subject | Brain -- Research | en_GB |
dc.subject | Axons -- Diseases | en_GB |
dc.title | L-lactate reduces ischemia-induced oligodendrocyte injury and modulates white matter HCA1 expression in a mouse MCAO model | en_GB |
dc.type | other | en_GB |
dc.rights.holder | The copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder | en_GB |
dc.description.reviewed | N/A | en_GB |
dc.contributor.creator | Vella, Jasmine | - |
dc.contributor.creator | Zammit, Christian | - |
dc.contributor.creator | Zammit, Robert | - |
dc.contributor.creator | Borg, Daniel | - |
dc.contributor.creator | Valentino, Mario | - |
Appears in Collections: | Scholarly Works - FacM&SPB |
Files in This Item:
File | Description | Size | Format | |
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Llactate_reduces_ischemia_induced_oligodendrocyte_injury_and_modulates_white_matter_HCA1_expression_in_a_mouse_MCAO_model. MMSC. 2018.pdf | 1.07 MB | Adobe PDF | View/Open |
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