Please use this identifier to cite or link to this item: https://www.um.edu.mt/library/oar/handle/123456789/55743
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dc.contributor.authorBorg, Michael Angelo-
dc.contributor.authorCamilleri, Liberato-
dc.date.accessioned2020-05-11T08:15:20Z-
dc.date.available2020-05-11T08:15:20Z-
dc.date.issued2019-
dc.identifier.citationBorg, M. A., & Camilleri, L. (2019). Broad-spectrum antibiotic use in Europe: more evidence of cultural influences on prescribing behaviour. Journal of Antimicrobial Chemotherapy, 74(11), 3379-3383.en_GB
dc.identifier.urihttps://www.um.edu.mt/library/oar/handle/123456789/55743-
dc.description.abstractObjectives: Sociocultural factors have been hypothesized as important drivers of inappropriate antibiotic prescribing in European ambulatory care. This study sought to assess whether they can also explain the reported variation in broad-spectrum antibiotic (Br-Ab) use among EU/European Economic Area (EEA) countries. Methods: Correlation and regression analysis were performed, using the bootstrap method, between Br-Ab ratios reported from 28 EU countries by the ECDC, and national Hofstede cultural dimensions and control of corruption (CoC) scores. Results: Significant bootstrapping correlation coefficients were identified between Br-Ab ratios and the dimension of uncertainty avoidance (UAI) as well as CoC. However, following both bootstrapping multiple regression and generalized linear modelling, only UAI was retained as the sole predictor. A logarithmic model explained 58.6% of the variation in European Br-Ab variability solely using national UAI scores (P,0.001). Conclusions: Br-Ab prescribing appears to be driven by the level of UAI within the country. Any interventions aimed at reducing Br-Ab in high-consuming EU/EEA countries need to address this cultural perception to maxi-mize their chances of success.en_GB
dc.language.isoenen_GB
dc.publisherOxford University Pressen_GB
dc.rightsinfo:eu-repo/semantics/openAccessen_GB
dc.subjectAntibioticsen_GB
dc.subjectAntibiotics -- Mechanism of actionen_GB
dc.subjectDrugs -- Prescribing -- Europeen_GB
dc.subjectDrugs -- Prescribing -- Cross-cultural studiesen_GB
dc.titleBroad-spectrum antibiotic use in Europe : more evidence of cultural influences on prescribing behaviouren_GB
dc.typearticleen_GB
dc.rights.holderThe copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder.en_GB
dc.description.reviewedpeer-revieweden_GB
dc.identifier.doi10.1093/jac/dkz312-
dc.publication.titleJournal of Antimicrobial Chemotherapyen_GB
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