Please use this identifier to cite or link to this item:
Full metadata record
DC FieldValueLanguage
dc.contributor.authorChen, Xiao-Cui-
dc.contributor.authorCao, Jun-Ji-
dc.contributor.authorWard, Tony J.-
dc.contributor.authorTian, Lin-Wei-
dc.contributor.authorNing, Zhi-
dc.contributor.authorGali, Nirmal Kumar-
dc.contributor.authorAquilina, Noel-
dc.contributor.authorHung-Lam Yim, Steve-
dc.contributor.authorQu, Linli-
dc.contributor.authorHo, Kin-Fai-
dc.identifier.citationChen, X. C., Cao, J. J., Ward, T. J., Tian, L. W., Ning, Z., Gali, N. K.,... Ho, K. F. (2020). Characteristics and toxicological effects of commuter exposure to black carbon and metal components of fine particles (PM2.5) in Hong Kong. Science of the Total Environment, 742, 140501.en_GB
dc.description.abstractEpidemiological studies have demonstrated significant associations between traffic-related air pollution and adverse health outcomes. Personal exposure to fine particles (PM2.5) in transport microenvironments and their toxicological properties remain to be investigated. Commuter exposures were investigated in public transport systems (including the buses and Mass Transit Railway (MTR)) along two sampling routes in Hong Kong. Real-time sampling for PM2.5 and black carbon (BC), along with integrated PM2.5 sampling, were performed during the warm and cold season of 2016–2017, respectively. Commuter exposure to BC during 3-hour commuting time exhibited a wider range, from 3.4 to 4.6 μg/m3 on the bus and 5.5 to 8.7 μg/m3 in MTR cabin (p < .05). PM2.5 mass and major chemical constituents (including organic carbon (OC), elemental carbon (EC), and metals) were analyzed. Cytotoxicity, including cellular reactive oxygen species (ROS) production, was determined in addition to acellular ROS generation. PM2.5 treatment promoted the ROS generation in a concentration-dependent manner. Consistent diurnal variations were observed for commuter exposure to BC and PM2.5 components, along with cellular and acellular ROS generation, which marked with two peaks during the morning (08:00–11:00) and evening rush hours (17:30–20:30). Commuter exposures in the MTR system were characterized by higher levels of PM2.5 and elemental components (e.g., Ca, Cr, Fe, Zn, Ba) compared to riding the bus, along with higher cellular and acellular ROS production (p < .01). These metals were attributed to different sources: rail tracks, wheels, brakes, and crustal origin. Weak to moderate associations were shown for the analyzed transition metals with PM2.5-induced cell viability and cellular ROS. Multiple linear regression analysis revealed that Ni, Zn, Mn, Fe, Ti, and Co attributed to cytotoxicity and ROS generation. These findings underscore the importance of commuter exposures and their toxic effects, urging effective mitigating strategies to protect human health.en_GB
dc.publisherElsevier BVen_GB
dc.subjectSoot -- China -- Hong Kongen_GB
dc.subjectTransition metalsen_GB
dc.subjectAntibody-dependent cell cytotoxicityen_GB
dc.subjectAir -- Pollution -- China -- Hong Kongen_GB
dc.titleCharacteristics and toxicological effects of commuter exposure to black carbon and metal components of fine particles (PM2.5) in Hong Kongen_GB
dc.rights.holderThe copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder.en_GB
dc.publication.titleScience of the Total Environmenten_GB
Appears in Collections:Scholarly Works - FacSciGeo

Items in OAR@UM are protected by copyright, with all rights reserved, unless otherwise indicated.