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Title: Male factors in ART outcome prediction
Authors: Brincat, Dale
Catania, Sarah
Schembri-Wismayer, Pierre
Calleja-Agius, Jean
Keywords: Reproductive technology
Biochemical markers
Infertility, Male
Issue Date: 2015
Publisher: Taylor & Francis
Citation: Brincat, D., Catania, S., Schembri Wismayer, P., & Calleja-Agius, J. (2015). Male factors in ART outcome prediction. Gynecological Endocrinology, 31(3), 169-175.
Abstract: Paternal influences on reproduction are significant causing about half of the infertile couples to turn to assisted reproductive techniques. Due to the increasing proportion of infertile couples adopting to conceive by in vitro fertilisation (IVF), predicting outcomes is of ever increasing importance. Since pregnancy rates following IVF are still quite low, prognostic information is very helpful in clinical decisions. Although significant research has been done on the maternal influence, male factor infertility is relatively understudied. To date, potential predictors include: method of fertilisation, age, reactive oxygen species, sperm quality parameters and DNA fragmentation. Predictors under investigation which show promising signs, even though there is no clear cut consensus on the predictive value to date include: folate and homocysteine, anti müllerian hormone measurement, environmental factors, body mass index, smoking, male age, stress, some subsets of antisperm antibodies and epigenetic features.
Appears in Collections:Scholarly Works - FacM&SAna

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