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dc.contributor.authorCalleja-Agius, Jean
dc.contributor.authorMuscat Baron, Yves
dc.contributor.authorBrincat, Mark P.
dc.identifier.citationMenopause International. 2007, Vol.13(2), p.60-64en_GB
dc.description.abstractCutaneous ageing manifests itself as a progressive reduction in maximum function and reserve capacity of skin tissue. It is not a unique and uniform biological event. Skin comprises three layers: epidermis, dermis and subcutaneous tissue. Collagen atrophy is a major factor in skin ageing. There is a strong correlation between skin collagen loss and estrogen deficiency due to the menopause. Skin ageing, especially in the face, is associated with a progressive increase in extensibility and a reduction in elasticity. With increasing age, the skin also becomes more fragile and susceptible to trauma, leading to more lacerations and bruising. Furthermore, wound healing is impaired in older women. Estrogen use after the menopause increases collagen content, dermal thickness and elasticity, and it decreases the likelihood of senile dry skin. Large-scale clinical trials are necessary to help make informed recommendations regarding postmenopausal estrogen use and its role in the prevention of skin ageing.en_GB
dc.publisherMenopause Internationalen_GB
dc.subjectSkin -- Agingen_GB
dc.subjectSkin -- Physiologyen_GB
dc.subjectMenopause -- Hormone therapyen_GB
dc.subjectHormone therapyen_GB
dc.titleSkin ageingen_GB
dc.rights.holderThe copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder.en_GB
Appears in Collections:Scholarly Works - FacM&SAna
Scholarly Works - FacM&SOG

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