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DC Field | Value | Language |
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dc.contributor.author | Momeni, Jamal | - |
dc.contributor.author | Parejo, Melanie | - |
dc.contributor.author | Nielsen, Rasmus O. | - |
dc.contributor.author | Langa, Jorge | - |
dc.contributor.author | Montes, Iratxe | - |
dc.contributor.author | Papoutsis, Laetitia | - |
dc.contributor.author | Farajzadeh, Leila | - |
dc.contributor.author | Bendixen, Christian | - |
dc.contributor.author | Căuia, Eliza | - |
dc.contributor.author | Charrière, Jean-Daniel | - |
dc.contributor.author | Coffey, Mary F. | - |
dc.contributor.author | Costa, Cecilia | - |
dc.contributor.author | Dall’Olio, Raffaele | - |
dc.contributor.author | De la Rúa, Pilar | - |
dc.contributor.author | Drazic, M. Maja | - |
dc.contributor.author | Filipi, Janja | - |
dc.contributor.author | Galea, Thomas | - |
dc.contributor.author | Golubovski, Miroljub | - |
dc.contributor.author | Gregorc, Ales | - |
dc.contributor.author | Grigoryan, Karina | - |
dc.contributor.author | Hatjina, Fani | - |
dc.contributor.author | Ilyasov, Rustem | - |
dc.contributor.author | Ivanova, Evgeniya | - |
dc.contributor.author | Janashia, Irakli | - |
dc.contributor.author | Kandemir, Irfan | - |
dc.contributor.author | Karatasou, Aikaterini | - |
dc.contributor.author | Kekecoglu, Meral | - |
dc.contributor.author | Kezic, Nikola | - |
dc.contributor.author | Matray, Enikö Sz. | - |
dc.contributor.author | Mifsud, David | - |
dc.contributor.author | Moosbeckhofer, Rudolf | - |
dc.contributor.author | Nikolenko, Alexei G. | - |
dc.contributor.author | Papachristoforou, Alexandros | - |
dc.contributor.author | Petrov, Plamen | - |
dc.contributor.author | Pinto, M. Alice | - |
dc.contributor.author | Poskryakov, Aleksandr V. | - |
dc.contributor.author | Sharipov, Aglyam Y. | - |
dc.contributor.author | Siceanu, Adrian | - |
dc.contributor.author | Soysal, M. Ihsan | - |
dc.contributor.author | Uzunov, Aleksandar | - |
dc.contributor.author | Zammit-Mangion, Marion | - |
dc.contributor.author | Vingborg, Rikke | - |
dc.contributor.author | Bouga, Maria | - |
dc.contributor.author | Kryger, Per | - |
dc.contributor.author | Meixner, Marina D. | - |
dc.contributor.author | Estonba, Andone | - |
dc.date.accessioned | 2021-02-11T08:11:19Z | - |
dc.date.available | 2021-02-11T08:11:19Z | - |
dc.date.issued | 2021 | - |
dc.identifier.citation | Momeni, J., Parejo, M., Nielsen, R. O., Langa, J., Montes, I., Papoutsis, L., ... & Estonba, A. (2021). Authoritative subspecies diagnosis tool for European honey bees based on ancestry informative SNPs. BMC Genomics, 22(1), 1-12. | en_GB |
dc.identifier.uri | https://www.um.edu.mt/library/oar/handle/123456789/68879 | - |
dc.description.abstract | Background: With numerous endemic subspecies representing four of its five evolutionary lineages, Europe holds a large fraction of Apis mellifera genetic diversity. This diversity and the natural distribution range have been altered by anthropogenic factors. The conservation of this natural heritage relies on the availability of accurate tools for subspecies diagnosis. Based on pool-sequence data from 2145 worker bees representing 22 populations sampled across Europe, we employed two highly discriminative approaches (PCA and FST) to select the most informative SNPs for ancestry inference. | en_GB |
dc.description.abstract | Results: Using a supervised machine learning (ML) approach and a set of 3896 genotyped individuals, we could show that the 4094 selected single nucleotide polymorphisms (SNPs) provide an accurate prediction of ancestry inference in European honey bees. The best ML model was Linear Support Vector Classifier (Linear SVC) which correctly assigned most individuals to one of the 14 subspecies or different genetic origins with a mean accuracy of 96.2% ± 0.8 SD. A total of 3.8% of test individuals were misclassified, most probably due to limited differentiation between the subspecies caused by close geographical proximity, or human interference of genetic integrity of reference subspecies, or a combination thereof. | en_GB |
dc.description.abstract | Conclusions: The diagnostic tool presented here will contribute to a sustainable conservation and support breeding activities in order to preserve the genetic heritage of European honey bees. | en_GB |
dc.language.iso | en | en_GB |
dc.publisher | BMC | en_GB |
dc.rights | info:eu-repo/semantics/openAccess | en_GB |
dc.subject | Insects -- Malta | en_GB |
dc.subject | Hymenoptera -- Malta | en_GB |
dc.subject | Apidae -- Malta | en_GB |
dc.subject | Apis (Insects) -- Malta | en_GB |
dc.subject | Honeybee -- Malta | en_GB |
dc.subject | Honeybee -- Conservation | en_GB |
dc.subject | Bees -- Conservation | en_GB |
dc.subject | Biodiversity -- Malta | en_GB |
dc.title | Authoritative subspecies diagnosis tool for European honey bees based on ancestry informative SNPs | en_GB |
dc.type | article | en_GB |
dc.rights.holder | The copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder. | en_GB |
dc.description.reviewed | peer-reviewed | en_GB |
dc.identifier.doi | 10.1186/s12864-021-07379-7 | - |
dc.publication.title | BMC Genomics | en_GB |
Appears in Collections: | Scholarly Works - InsESRSF |
Files in This Item:
File | Description | Size | Format | |
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momeni_etal_2021.pdf | 1.08 MB | Adobe PDF | View/Open |
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