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dc.identifier.citationAttard, E. (1995). Ecballium elaterium L. : a source of cucurbitacin E, a cytotoxic tetracyclic triterpenoid (Master’s dissertation).en_GB
dc.description.abstractEcballium elaterium L. is a local medicinal plant which stores several compounds, which fall under the name of cucurbitacins. Cucurbitacin E is obtained from the dried fruit juice and has been found to possess cytotoxic properties. In this dissertation a comparative study, regarding the cytotoxicity of cucurbitacin E and busulphan on two cell lines (ovarian and stomach cell lines), was carried out. AIMS: The investigation was divided into two parts: Part I: To determine the inhibition of ovarian and stomach cancer cell growth when these were exposed to different concentrations of the two compounds. The cell viability was followed up from day 0 to day 11 and using the Exclusion Dye Technique (Trypan Blue as dye). Part II: To observe any morphological changes provoked by the cytotoxic agents on the ovarian cancer cell line. The cells were examined after an hour and after twenty-four hours. The Papanicolau Staining Procedure was used.en_GB
dc.subjectMedicinal plants -- Maltaen_GB
dc.subjectCucumbers -- Maltaen_GB
dc.subjectCell linesen_GB
dc.subjectPlant toxinsen_GB
dc.titleEcballium elaterium L. : a source of cucurbitacin E, a cytotoxic tetracyclic triterpenoiden_GB
dc.rights.holderThe copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder.en_GB
dc.publisher.institutionUniversity of Maltaen_GB
dc.publisher.departmentInstitute of Earth Systemsen_GB
dc.contributor.creatorAttard, Everaldo-
Appears in Collections:Dissertations - InsES - 1994-2013

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