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dc.identifier.citationBorg, H. (1998). Crataegus monogyna Jacq. : a source of oleanolic acid, a potential angiotensin-converting enzyme inhibitor (Master’s dissertation).en_GB
dc.description.abstractCrataeugus monogyna Jacq., a local wild medicinal plant, contains several compounds that possess various pharmacological properties, including effects on the cardiovascular system. The compound of interest in this dissertation was oleanolic acid, a penacyclic triterpenoid present in the free state of salt form. This investigation was aimed at the extraction of oleanolic acid and determination of its quality and quantity by several analytical assays. Oleanolic acid (0.0496%) was extracted from air-dried fruit. This involved Soxhlet extraction, partitioning of the compound in diethyl ether, dissolution in acetone and preparative layer chromatography, successively. The purity of oleanolic acid was determined by TLC, IR and UV spectroscopy. The ethanolic extract was tested for other compounds by spectrophotometric and colorimetric techniques. It resulted that this extract contained favonoids and coumarins, but no catecholamines or organic acids. The quantity of triterpenoids obtrained from the plant material was 0.8976%, of which oleanolic acid constituted only 5.53%. Therefore the yield of oleanolic acid by the ripe fruit was low.en_GB
dc.subjectMedicinal plants -- Maltaen_GB
dc.subjectBotanical chemistryen_GB
dc.subjectChromatographic analysisen_GB
dc.subjectCrataegus monogynaen_GB
dc.subjectAngiotensin converting enzyme -- Inhibitors -- Therapeutic useen_GB
dc.titleCrataegus monogyna Jacq. : a source of oleanolic acid, a potential angiotensin-converting enzyme inhibitoren_GB
dc.rights.holderThe copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder.en_GB
dc.publisher.institutionUniversity of Maltaen_GB
dc.publisher.departmentInstitute of Earth Systemsen_GB
dc.contributor.creatorBorg, Henrietta (1998)-
Appears in Collections:Dissertations - InsES - 1994-2013

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