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dc.contributor.authorPace, Tamsin-
dc.contributor.authorMifsud, Janet-
dc.contributor.authorEllul-Micallef, Roger-
dc.contributor.authorFenech, A.-
dc.contributor.authorCali-Corleo, R.-
dc.identifier.citationPace, T., Mifsud, J., Ellul-Micallef, R., Fenech, A., & Cali-Corleo, R. (2004). The use of a non-sedating antihistamine in a hyperbaric environment. Clinical and Experimental Pharmacology and Physiology, 31(11), A223.en_GB
dc.description.abstractAntihistamines are associated with drowsiness and are commonly taken by divers to relieve ENT symptoms and prevent serious injury, especially where the diver has no intention to discontinue diving to allow the infection or allergy to subside. Few studies have been conducted to test whether antihistamines aggravate nitrogen narcosis, cognitive or motor functions due to any alteration in their pharmacodynamics and pharmacokinetics. Study I was a randomised double-blind placebo-controlled study, involving 50 subjects. The means of the 2 groups did not differ for diving experience, blood cell counts, liver and renal function (P< 0.05). Scales used to assess the subject mood and degree of sedation did not elucidate any statistically significant differences prior to the study. [excerpt]en_GB
dc.publisherJohn Wiley & Sons, Inc.en_GB
dc.subjectClinical pharmacology -- Maltaen_GB
dc.subjectHyperbaric oxygenation -- Maltaen_GB
dc.subjectAllergy -- Maltaen_GB
dc.subjectAsthma -- Maltaen_GB
dc.subjectDiving -- Maltaen_GB
dc.titleThe use of a non-sedating antihistamine in a hyperbaric environmenten_GB
dc.rights.holderThe copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder.en_GB
dc.bibliographicCitation.conferencename8th World Conference on Clinical Pharmacology and Therapeuticsen_GB
dc.bibliographicCitation.conferenceplaceBrisbane, Australia, 1-6/08/2004en_GB
dc.publication.titleClinical and Experimental Pharmacology and Physiologyen_GB
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