A mutation in the LRP4 gene is associated with bone mineral density in Maltese postmenopausal women

Formosa, Melissa Marie; Borg, Joseph J.; Bezzina Wettinger, Stephanie; Farrugia, Rosienne; Xuereb-Anastasi, Angela

Please use this identifier to cite or link to this item: https://www.um.edu.mt/library/oar/handle/123456789/93233

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DC Field	Value	Language
dc.contributor.author	Formosa, Melissa Marie	-
dc.contributor.author	Borg, Joseph J.	-
dc.contributor.author	Bezzina Wettinger, Stephanie	-
dc.contributor.author	Farrugia, Rosienne	-
dc.contributor.author	Xuereb-Anastasi, Angela	-
dc.date.accessioned	2022-04-08T13:20:45Z	-
dc.date.available	2022-04-08T13:20:45Z	-
dc.date.issued	2014-05	-
dc.identifier.citation	Formosa, M. M., Borg, J., Bezzina-Wettinger, S., Farrugia, R., & Xuereb-Anastasi, A. (2014). A mutation in the LRP4 gene is associated with bone mineral density in Maltese postmenopausal women. European Journal of Human Genetics, 22(s1), 97.	en_GB
dc.identifier.uri	https://www.um.edu.mt/library/oar/handle/123456789/93233	-
dc.description.abstract	BACKGROUND: Osteoporosis is a hereditary multifactorial skeletal disease characterised by low bone mass and increased fracture susceptibility. The low-density lipoprotein receptor-related protein 4 (LRP4) controls the actions of sclerostin which is a known inhibitor of the Wingless (Wnt)/Beta (β) catenin pathway involved in bone formation.	en_GB
dc.description.abstract	OBJECTIVE: To evaluate the effect of two non-synonymous coding polymorphisms rs6485702 (A>G) and rs2306033 (C>T) in relation to Bone Mineral Density (BMD) and different low-trauma fractures in Maltese postmenopausal women.	en_GB
dc.description.abstract	[excerpt]	en_GB
dc.language.iso	en	en_GB
dc.publisher	Springer Nature Limited	en_GB
dc.rights	info:eu-repo/semantics/restrictedAccess	en_GB
dc.subject	Osteoporosis -- Genetic aspects	en_GB
dc.subject	Bone density	en_GB
dc.subject	Osteoporosis in women -- Malta	en_GB
dc.title	A mutation in the LRP4 gene is associated with bone mineral density in Maltese postmenopausal women	en_GB
dc.type	article	en_GB
dc.rights.holder	The copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder.	en_GB
dc.bibliographicCitation.conferencename	47th European Society of Human Genetics Conference	en_GB
dc.bibliographicCitation.conferenceplace	Milan, Italy, 31/05-3/06/2014	en_GB
dc.description.reviewed	peer-reviewed	en_GB
dc.publication.title	European Journal of Human Genetics	en_GB
Appears in Collections:	Scholarly Works - FacHScABS

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