Polymorphisms in the Osteoprotegerin gene are associated with bone mineral density and fracture risk in Maltese postmenopausal women

Formosa, Melissa Marie; Xuereb-Anastasi, Angela

Please use this identifier to cite or link to this item: https://www.um.edu.mt/library/oar/handle/123456789/93267

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DC Field	Value	Language
dc.contributor.author	Formosa, Melissa Marie	-
dc.contributor.author	Xuereb-Anastasi, Angela	-
dc.date.accessioned	2022-04-08T15:58:48Z	-
dc.date.available	2022-04-08T15:58:48Z	-
dc.date.issued	2016	-
dc.identifier.citation	Formosa, M. M., & Xuereb-Anastasi, A. (2016). Polymorphisms in the Osteoprotegerin gene are associated with bone mineral density and fracture risk in Maltese postmenopausal women. European Journal of Human Genetics, 24, P04.072.	en_GB
dc.identifier.uri	https://www.um.edu.mt/library/oar/handle/123456789/93267	-
dc.description.abstract	INTRODUCTION: Osteoprotegerin (OPG) is a decoy receptor for the Receptor activator of nuclear factor kappa-B ligand (RANKL), which blocks the interaction between RANKL and RANK thereby inhibiting osteoclastogenesis and bone resorption. Four polymorphisms within the OPG gene, and one polymorphism located 43kB upstream of OPG were analysed in relation to bone mineral density (BMD) and low-trauma fractures in Maltese postmenopausal women.	en_GB
dc.description.abstract	METHODS: A case-control collection of 1045 women was used. Cases were women who suffered a fracture, whereas controls had no fracture history. Genotyping was performed by polymerase chain reaction followed by restriction fragment length polymorphism or real-time PCR.	en_GB
dc.description.abstract	[excerpt]	en_GB
dc.language.iso	en	en_GB
dc.publisher	Springer	en_GB
dc.rights	info:eu-repo/semantics/restrictedAccess	en_GB
dc.subject	Osteoprotegerin	en_GB
dc.subject	Bone density	en_GB
dc.subject	Fractures -- Risk factors	en_GB
dc.subject	Menopause -- Complications	en_GB
dc.subject	Genetic polymorphisms	en_GB
dc.title	Polymorphisms in the Osteoprotegerin gene are associated with bone mineral density and fracture risk in Maltese postmenopausal women	en_GB
dc.type	article	en_GB
dc.rights.holder	The copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder.	en_GB
dc.bibliographicCitation.conferencename	49th European Society of Human Genetics Conference	en_GB
dc.bibliographicCitation.conferenceplace	Barcelona, Spain, 21-24/05/2016	en_GB
dc.description.reviewed	peer-reviewed	en_GB
dc.publication.title	European Journal of Human Genetics	en_GB
Appears in Collections:	Scholarly Works - FacHScABS

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