Please use this identifier to cite or link to this item:
https://www.um.edu.mt/library/oar/handle/123456789/93810
Title: | Maternal exposure to influenza and paranoid schizophrenia |
Authors: | Grech, Anton Takei, Noriyoshi Murray, Robin M. |
Keywords: | Schizophrenia -- Etiology Prenatal influences Schizophrenia -- Genetic aspects Schizophrenia -- Pathophysiology Schizophrenia -- Diagnosis |
Issue Date: | 1997 |
Publisher: | Elsevier |
Citation: | Grech, A., Takei, N., & Murray, R. M. (1997). Maternal exposure to influenza and paranoid schizophrenia. Schizophrenia Research, 26(2-3), 121-125. |
Abstract: | Previous research has suggested that schizophrenics exposed to influenza in the second trimester have more delusions of jealousy, delusions of reference and suspiciousness. We therefore hypothesised that the risk-increasing effect of in utero exposure to influenza would be particularly demonstrable in paranoid schizophrenia. We studied patients with an ICD diagnosis of schizophrenia in England and Wales who were born each month between 1923 and 1965 (N=17 247). Chi-square test for trend showed that an increase in influenza exposure level during the fifth month of gestation was accompanied by an increase in the proportion of patients with paranoid schizophrenia. However, logistic regression analysis including sex, seasonality and birth period in the model resulted in the loss of any significant association between in utero exposure to influenza and the development of paranoid schizophrenia, the loss of this significance being mainly accounted for by birth period. Therefore, the association between in utero exposure to influenza and subsequent development of paranoid schizophrenia we hypothesised was not supported by our data. |
URI: | https://www.um.edu.mt/library/oar/handle/123456789/93810 |
Appears in Collections: | Scholarly Works - FacM&SPsy |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Maternal exposure to influenza and paranoid schizophrenia.pdf Restricted Access | 63.18 kB | Adobe PDF | View/Open Request a copy |
Items in OAR@UM are protected by copyright, with all rights reserved, unless otherwise indicated.