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Title: | Comparison of manual and semi-automatic measuring techniques in MSCT scans of patients with lymphoma : a multicentre study |
Authors: | Höink, A. J. Weßling, J. Koch, R. Schülke, C. Kohlhase, N. Wassenaar, L. Mesters, R. M. D'Anastasi, Melvin Fabel, M. Wulff, A. Pinto dos Santos, D. Kießling, A. Graser, A. Dicken, V. Karpitschka, M. Bornemann, L. Heindel, W. Buerke, B. |
Keywords: | Tomography -- Data processing Multidetector computed tomography Lymph nodes -- Diseases -- Diagnosis -- Data processing Lymph nodes -- Tomography Lymphomas -- Cancer -- Patients |
Issue Date: | 2014 |
Publisher: | Springer |
Citation: | Höink, A. J., Weßling, J., Koch, R., Schülke, C., Kohlhase, N., Wassenaar, L.,...Buerke, B. (2014). Comparison of manual and semi-automatic measuring techniques in MSCT scans of patients with lymphoma: a multicentre study. European Radiology, 24(11), 2709-2718. |
Abstract: | Objectives Multicentre evaluation of the precision of semiautomatic 2D/3D measurements in comparison to manual, linear measurements of lymph nodes regarding their interobserver variability inmulti-slice CT (MSCT) of patients with lymphoma.Methods MSCT data of 63 patients were interpreted before and after chemotherapy by one/two radiologists in five university hospitals. In 307 lymph nodes, short (SAD)/long (LAD) axis diameter and WHO area were determined manually and semi-automatically. Volume was solely calculated semi-automatically. To determine the precision of the individual parameters, a mean was calculated for every lymph node/parameter. Deviation of the measured parameters from this mean was evaluated separately. Statistical analysis entailed intraclass correlation coefficients (ICC) and Kruskal–Wallis tests. Results Median relative deviations of semi-automatic parameters were smaller than deviations of manually assessed parameters, e.g. semi-automatic SAD 5.3 vs. manual 6.5 %. Median variations among different study sites were smaller if the measurement was conducted semi-automatically, e. g. manual LAD 5.7/4.2 % vs. semi-automatic 3.4/3.4 %. Semi-automatic volumetry was superior to the other parameters (2.8 %). Conclusions Semi-automatic determination of different lymph node parameters is (compared to manually assessed parameters) associated with a slightly greater precision and a marginally lower inter-observer variability. These results are with regard to the increasing mobility of patients among different medical centres and in relation to the quality management of multicentre trials of importance. |
URI: | https://www.um.edu.mt/library/oar/handle/123456789/94373 |
Appears in Collections: | Scholarly Works - FacM&SCRNM |
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