Dr Duncan Ayers

Dr Duncan Ayers

Dr Duncan Ayers

 B.Pharm.(Hons),M.Sc.(Manc.),Ph.D.(Manc.),M.R.Pharm.S.,A.M.R.S.C.

Research Support Officer IV

Room 040
Level -1
Biomedical Sciences Building
University of Malta
Msida
  +356 2545 3047
Research Interests

- RNA interference (RNAi) based diagnostic & therapeutics research in the context of tumor development

- Influence of gene, miRNA and other non-coding RNA expression in the development of human disease conditions

- High throughput semi-/quantitative gene (or miRNA, lncRNA, etc.) analytical techniques such as RT-qPCR and microarray
platform utilization

- Development of nanoparticle – based drug delivery systems for RNAi-based Therapeutics


Journal Publications

- Ayers D, Platt M, Javad F, Day PJ. Human papilloma virus strain detection
utilising custom-designed oligonucleotide microarrays. Methods Mol Biol.
2011;688:75-95.
http://www.ncbi.nlm.nih.gov/pubmed/20938834

- Logan J A, Kelly M, Ayers D, Shipilis N, Day P. Systems biology and modelling in
neuroblastoma: practicalities and perspectives. Expert Rev Mol Diagn. 2010
Mar;10(2):131-45.
http://www.expert-reviews.com/doi/pdf/10.1586/erm.10.4

- Duncan Ayers, Philip JR Day. Unlocking the potential of RNA interference as a therapeutic tool.
MMJ 21 (2009); 3:13-19.
http://www.um.edu.mt/umms/mmj/showpdf.php?article=252

- Duncan Ayers, Dylan N Clements, Fiona Salway, Philip JR Day. Expression stability of commonly used reference genes in
canine articular connective tissues.
BMC Veterinary Research 2007, 3:7.
http://www.biomedcentral.com/1746-6148/3/7/abstract


Book Publications

- Duncan Ayers. Implications of miRNA-directed gene silencing in cancer.
Book chapter included in: RNAi Technology. Edited by Drs. R.K. Gaur, Y. Gafni,
Pradeep Sharma and Vijai Kumar Gupta (Science Publishers, USA; 2011).

- Duncan Ayers, Mark Platt, Farzad Javad, Philip J R Day. Human Papilloma
Virus strand detection utilising custom-designed oligonucleotide microarrays.
Book chapter included in: PCR Mutation Detection Protocols, Vol.2. Edited by Drs.
B. Theophilus & R. Rapley (Humana Press, USA; 2010).

Selected Citations


Selection of reference genes for normalisation of real-time RT-PCR in brain-stem death injury in Ovis aries
Passmore M, Nataatmadja M, Fraser JF
BMC Molecular Biology 2009, 10:72 (23 July 2009)


Streptococcus pneumoniae nasopharyngeal colonization induces type I interferons and interferon-induced gene expression
Joyce EA, Popper SJ, Falkow S
BMC Genomics 2009, 10:404 (27 August 2009)
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