Professor Balzan’s work is focused on the following areas:
(1) The effect of aspirin on apoptosis in yeast cells
(2) Protein-mitochondrial targeting in yeast.
Yeast (Saccharomyces cerevisiae) is being used as a eukaryotic model. It has powerful experimental advantages for the study of human disease genes and feasible therapies. Investigations of the mechanisms by which aspirin and other nonsteroidal anti- inflammatory drugs (NSAIDs) function are very important because they may contribute towards a better understanding of the early stages of apoptosis and oxidative stress before cell damage has become irreversible.
Professor Balzan is also a reviewer for BBA - Biochimica et Biophysica Acta - General Subjects, and for Experimental Cell Research.