| CODE | PHB3501 | ||||||||||||
| TITLE | Applied Molecular Bioscience 3: Bioanalysis | ||||||||||||
| UM LEVEL | 03 - Years 2, 3, 4 in Modular Undergraduate Course | ||||||||||||
| MQF LEVEL | 6 | ||||||||||||
| ECTS CREDITS | 6 | ||||||||||||
| DEPARTMENT | Physiology and Biochemistry | ||||||||||||
| DESCRIPTION | This study-unit introduces students to the method of identification of a bioactive molecule, its isolation from source and the scaling up of its extraction. This is followed by a series of bioanalytical techniques that include forms of bioimaging that may be applied to the characterization of the bioactive molecule and the elucidation of its effect on biological systems. Study-unit Aims: This study-unit aims to provide students with the opportunity to consolidate and apply scientific principles that they have learnt in previously completed study-units to biotechnological applications. Through this unit, students will acquire the understanding and basic skills necessary to formulate a process of identification, extraction, characterisation of a bioactive molecule and to perform functional studies on cells in culture by the application of various molecular bioanalytical techniques and imaging. Learning Outcomes: 1. Knowledge & Understanding: By the end of the study-unit the student will be able to: - Describe the required criteria for the identification of an appropriate natural source for bioactive molecules; - Discuss aspects of toxicity; - Explain the chemical principles of extraction; - Discuss the methodology necessary for preparative extractions; - Describe the basic principles of the relevant bioanalytical and biophysical technology; and - Discuss the different applications of bioimaging. 2. Skills: By the end of the study-unit the student will be able to: - Assess biological characteristics of the natural source of the bioactive molecule; - Formulate a process of identification of an appropriate natural source for bioactive molecules; - Assess toxicity; - Apply chemical principles to the process of extraction and separation; - Devise protocols of extraction; - Scale up process of extraction; - Apply technology to prove a concept; and - Interpret data from different bioanalytical techniques. Main Text/s and any supplementary readings: Gault, V. A and McClenaghanm N. V. Understanding Bioanaytical Chemistry: Principles and Applications. 1st edition. New York Wiley-Blackman Publishers. 2009. |
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| STUDY-UNIT TYPE | Independent Study, Lecture, Practicum & Seminar | ||||||||||||
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The University makes every effort to ensure that the published Courses Plans, Programmes of Study and Study-Unit information are complete and up-to-date at the time of publication. The University reserves the right to make changes in case errors are detected after publication.
The availability of optional units may be subject to timetabling constraints. Units not attracting a sufficient number of registrations may be withdrawn without notice. It should be noted that all the information in the description above applies to study-units available during the academic year 2023/4. It may be subject to change in subsequent years. |
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