| CODE | PHR2304 | ||||||
| TITLE | Pharmaceutics 2 | ||||||
| UM LEVEL | 02 - Years 2, 3 in Modular Undergraduate Course | ||||||
| MQF LEVEL | Not Applicable | ||||||
| ECTS CREDITS | 6 | ||||||
| DEPARTMENT | Pharmacy | ||||||
| DESCRIPTION | - Dispersed systems: advantages and disadvantages of dispersed systems, types of dispersed systems, classification of dispersed systems according to particle size - Surfactants: hydrophilic-lipophilic balance (HLB), pharmaceutical uses of surfactants, chemical classification of surfactants, HLB calculations - Solutions: physicochemical principles underlying drug solubility of slightly soluble electrolytes and weak electrolytes, effect of pH and solvents, co-solvency. - Suspensions: characteristics, physicochemical principles underlying the sedimentation, wetting, rheology, crystal growth and particle interaction of solids in suspension, suspension formulation, types of powders used in suspensions. - Emulsions: detection of emulsion type, theories of emulsification, physical stability and rheology of emulsions, emulsion components, optimisation factors, emulsification techniques. - Percutaneous drug delivery: Percutaneous absorption mechanism, topical dosage forms, various formulations, components and optimisation factors, manufacture and packaging - Aerosols: Dosage Form, propellants, surfactants, principle, systems, container and valve assembly, various formulations and biophysical issues, manufacture, packaging and labelling - Medicinal gases: Pharmaceutical gases, EU Directives and Harmonized standards, Management by hospital pharmacists - Practical sessions in the pharmaceutical industry Study unit aims: o to provide students with a comprehensive insight and clear understanding of the properties and aspects of different preparations that may be considered when formulating systems to be used as medicinal products. o to introduce students to practical examples in the pharmaceutical industry Learning outcomes: 1. Knowledge & Understanding: By the end of the study-unit the student will be able to: o give practical examples of practices in the pharmaceutical industry o comprehend how properties of materials influence the choice of formulating a drug delivery system, o understand the key properties of each individual preparation 2. Skills: By the end of the study-unit the student will be able to: o identify the characteristics of different drug delivery systems o identify the characteristics of different drug delivery systems, o acquire mathematical skills needed in pharmaceutical preparations. Main texts: o Sinko PJ. Martin's physical pharmacy and pharmaceutical sciences. USA: Lippincott Williams and Wilkins. 2006. o British Pharmacopoeia Commission Secretariat of the Medicines and Healthcare products Regulatory Agency. British Pharmacopoeia 2011. London: The Stationery Office. o Gennaro, A, Remington: The Science and Practice of Pharmacy. USA: Lippincott Williams & Wilkins. 21st edn 2000. |
||||||
| RULES/CONDITIONS | Before TAKING THIS UNIT YOU MUST TAKE PHR1303 | ||||||
| STUDY-UNIT TYPE | Lecture, Tutorial and Practical | ||||||
| METHOD OF ASSESSMENT |
|
||||||
| LECTURER/S | Edwina V. Brejza Marie Claire Zammit |
||||||
|
The University makes every effort to ensure that the published Courses Plans, Programmes of Study and Study-Unit information are complete and up-to-date at the time of publication. The University reserves the right to make changes in case errors are detected after publication.
The availability of optional units may be subject to timetabling constraints. Units not attracting a sufficient number of registrations may be withdrawn without notice. It should be noted that all the information in the description above applies to study-units available during the academic year 2023/4. It may be subject to change in subsequent years. |
|||||||