Study-Unit Description

Study-Unit Description


CODE CHE1004

 
TITLE Introduction to Chemistry in the Life Sciences

 
LEVEL 01 - Year 1 in Modular Undergraduate Course

 
ECTS CREDITS 4

 
DEPARTMENT Chemistry

 
DESCRIPTION 1. Solutions
Concentration (g/dm3, molarity, % by volume, % by mass, ppm, ppb)
Standard solutions
Dilutions, and related calculations

2. Second Law of Thermodynamics
A basic treatment of the relationship ?G = ?H - T?S, spontaneity of reactions
Related relationships: ?? = ?E + P?V,??G = ?GO - RTlnK

3. Chemical Kinetics
Basic treatment: rate versus concentration, energy profiles, order of reaction, elementary step reactions and mechanisms, transition state
Mathematical notation
Rate laws
Catalysed and uncatalysed reactions
Reactions catalysed by enzymes, the Michaelis-Menten model

4. Basic Spectroscopy
The electromagnetic spectrum
The interaction of electromagnetic radiation with atoms and molecules
Quantisation of energy, E = h?
Basic theory of: emission and absorption spectra, fluorescence spectra, UV-visible spectroscopy, mass spectroscopy

5. Redox reactions
Definitions
Electrolytic cell - the basics
The concept of reduction potentials
Using reduction potentials to predict redox reactions
The Nernst equation
?G = ?nFE
Use of electrochemistry in analysis: ion-selective electrodes

6. Organic Chemistry
Homologous series, functional groups
Reactivity and stereochemistry of the different functional groups
The SN1 and SN2 mechanisms
The E1 and E2 mechanisms
The mechanism of electrophilic substitution in aromatic compounds

Main Texts

- Musumeci, M. M., Introduction to Chemistry in the Life Science - Notes, 2005
- Atkins, P., De Paula, J., Elements of Physical Chemistry, Oxford University Press, 2005 (ISBN 0199271836)
- Hollas, J. M., Basic Atomic and Molecular Spectroscopy, The Royal Society of Chemistry, 2002 (ISBN 0854046674)
- Morrison, R. T., Boyd, R. N., Organic Chemistry, Pearson US Imports & PHIPEs, 1999 (ISBN 0132678160)

Further References

- Jones, A., et al., Access to Chemistry, The Royal Society of Chemistry, 1999 (ISBN 0854045643)
- Holman, J., Hill, G., Chemistry in Context, Nelson Thornes, 2000 (ISBN 0174482760)
- Ramsden, E. N., A-Level Chemistry: Core Text, Nelson Thornes, 2000 (ISBN 0748752994)
- Lister, T., Renshaw, J., New Understanding Chemistry for Advanced Level, Nelson Thornes, 1999 (ISBN 0748739580)
- Stryer, L., et al., Biochemistry, W H Freeman & Co, 2002 (ISBN 0716746840)
- Depaula, J., Atkins, P. W., Physical Chemistry for the Life Sciences, Oxford University Press, 2005 (ISBN 0199280959)
- Mortimer, M., Taylor, P. G. (Eds.), Chemical Kinetics and Mechanism, The Royal Society of Chemistry, 2002 (ISBN 0854046704)
- Hammes, G. G., Thermodynamics and Kinetics for the Biological Sciences, John Wiley & Sons Inc., 2000 (ISBN 0471374911)
- Silverstein, R. M., The Spectrometric Identification of Organic Compounds, John Wiley and Sons, 2004 (ISBN 0471429139)
- Whittaker, D., Interpreting Organic Spectra, The Royal Society of Chemistry, 2000 (ISBN 0854046011)
- Anderson, R. J., Bendell, D., Organic Spectroscopic Analysis, The Royal Society of Chemistry, 2004 (ISBN 0854044760)
- Website: Spectroscopic Techniques
http://www.chemsoc.org/networks/learnnet/Spec_Techniques.htm

 
STUDY-UNIT TYPE Lecture

 
METHOD OF ASSESSMENT
Assessment Component/s Assessment Due Resit Availability Weighting
Online Examination (2 Hours) SEM1 Yes 100%

 
LECTURER/S Liana Vella Zarb

 
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