| CODE | CHE3240 | ||||||||||||
| TITLE | Separation Techniques and Analytical Chemistry | ||||||||||||
| UM LEVEL | 03 - Years 2, 3, 4 in Modular Undergraduate Course | ||||||||||||
| MQF LEVEL | 6 | ||||||||||||
| ECTS CREDITS | 4 | ||||||||||||
| DEPARTMENT | Chemistry | ||||||||||||
| DESCRIPTION | Content Section A: Separation Techniques Principles and Introduction. - Introduction to partition chromatography, principles of solute movement, capacity factor, selectivity factor, band resolution, theoretical plate, rate theory of chromatography, adsorption processes, band broadening, some common chromatographic techniques. - Solvent extraction: partition coefficient, distribution ratio D, pH dependence of D, extraction efficiency, multiple extractions, solvent extraction equilibria, selective extraction of metal ions, some practical extraction techniques, solid phase extractions. Gas chromatography. - Basic set-up, packed columns, capillary columns, column characteristics, support material, the liquid phase, temperature effects and programming, injection systems, universal detectors, modem detectors, column efficiency and conditions, qualitative and quantitative analysis, trouble shooting, Liquid chromatography. - Classification of liquid chromatography (LC), bonded-phase partition LC, LC columns and support packings, the mobile phase, HPLC universal detectors, modern HPLC detectors, HPIC, column efficiency and conditions, qualitative and quantitative analysis, trouble shooting. Ion-exchange separations. - Cation and anion exchange resins, resin characteristics, applications of ion-exchange chromatography. Section B: Analytical Chemistry Chromatographic/spectrophotometric hyphenated techniques. - GC-MS: direct coupling interface, sample ionization: electron impact, chemical ionization, quadrupole and ion trap analysers, total ion chromatograms, selected ion monitoring, GC-FTIR: flow cell interface, cold trapping interface, data handling and processes, LC-MS: direct introduction, thermospray and particle beam introduction, atmospheric pressure ionization. LC-FTIR: flow cell interface, solvent elimination. Fourier Transform Spectroscopy. - Fourier transformation, Michaelson interferometer, FTIR. Performance tests. - Confidence limit and interval, tests of significance, comparing two sets of data, comparing a set of data with a true value, comparing several sets of data. Measurement uncertainty, traceability, validation. - Measurement equation, cause and effect diagram, combined uncertainties, control charts, calibration, use of reference materials, SI units in chemical metrology, method and instrument validation. Recommended Texts: - Analytical Chemistry - Approved Text to the Federation of European Chemical Society Curriculum, Ed. Robert Keilner Pubi: Wiley-VCH (1998) - Christian Gary D., Analytical Chemistry, 5th Edn., Wiley. (1994). - Quality in the Analytical Chemistry Laboratory. Co-ordinating Author: Elizabeth Prichard. Publ: John Wiley (1997) Supplementary Reading: - Skoog Douglas A. and West Donald M., Analytical Chemistry 6th Edn |
||||||||||||
| STUDY-UNIT TYPE | Lecture | ||||||||||||
| METHOD OF ASSESSMENT |
|
||||||||||||
| LECTURER/S | David C. Magri |
||||||||||||
|
The University makes every effort to ensure that the published Courses Plans, Programmes of Study and Study-Unit information are complete and up-to-date at the time of publication. The University reserves the right to make changes in case errors are detected after publication.
The availability of optional units may be subject to timetabling constraints. Units not attracting a sufficient number of registrations may be withdrawn without notice. It should be noted that all the information in the description above applies to study-units available during the academic year 2023/4. It may be subject to change in subsequent years. |
|||||||||||||