CODE | CPH1904 | ||||||||
TITLE | Drug Formulations and Routes of Administration | ||||||||
UM LEVEL | 01 - Year 1 in Modular Undergraduate Course | ||||||||
MQF LEVEL | 5 | ||||||||
ECTS CREDITS | 4 | ||||||||
DEPARTMENT | Clinical Pharmacology and Therapeutics | ||||||||
DESCRIPTION | Drugs need to be available in a particular form and administered via a specific route for them to have a therapeutic effect on patients. This study-unit will provide students with a background to formulation development and address the various routes by which drugs are administered. An introduction to chemistry of drug design and formulation will be provided. The processes used for the formulation of different dosage forms and drug delivery systems will be addressed. The various means by which drugs are introduced in the body and their relevance to safety and effectiveness will be addressed. Study-unit Aims: The aim of the study-unit is to provide students with a foundation in drug formulation and the relationship between formulation and route of administration. Students will be exposed to both traditional and innovative approaches to formulation development as well as to the rationale behind the selection of the most appropriate route of administration for a given situation. Learning Outcomes: 1. Knowledge & Understanding By the end of the study-unit the student will be able to: - Define the basic terminology used in drug formulation; - Explain the basic physical chemistry of drug formulation; - Review innovative drug delivery systems; - Differentiate the various routes of drug administration; - Relate drug formulation to route of drug administration; - Discuss the effects of formulation and route of administration on patient outcomes. 2. Skills By the end of the study-unit the student will be able to: - Differentiate between different formulations; - Differentiate between the various routes of administration; - Relate formulation to drug development; - Evaluate the literature within the field of drug formulations; - Propose suitable routes of administration within the context of specific drugs, diseases and patient characteristics. Main Text/s and any supplementary readings: Main Texts: - Taylor K, Aulton M. Aulton's Pharmaceutics: The design and manufacture of medicines. 2007. Churchill Livingstone. - Allen LV, Popovich NG, Ansel HC. Ansel's Pharmaceutical Dosage Forms and Drug Delivery Systems 2010. Lippincott, Williams & Wilkins. Supplementary Texts: - Florence AT, Siepmann J. Modern Pharmaceutics, 5th Ed. Vol 1: Basic Principles and Systems (Drugs and the Pharmaceutical Sciences). 2009. Informa Healthcare. |
||||||||
STUDY-UNIT TYPE | Lecture and Independent Study | ||||||||
METHOD OF ASSESSMENT |
|
||||||||
LECTURER/S | Corinne Maria Bowman Maria A. Cordina (Co-ord.) Janet Mifsud Lorna West Mark Zammit |
||||||||
The University makes every effort to ensure that the published Courses Plans, Programmes of Study and Study-Unit information are complete and up-to-date at the time of publication. The University reserves the right to make changes in case errors are detected after publication.
The availability of optional units may be subject to timetabling constraints. Units not attracting a sufficient number of registrations may be withdrawn without notice. It should be noted that all the information in the description above applies to study-units available during the academic year 2024/5. It may be subject to change in subsequent years. |