Study-Unit Description

Study-Unit Description


CODE CPH5403

 
TITLE Clinical Toxicology and Management of Poisoning of Commonly Used Pharmaceuticals 1

 
LEVEL 05 - Postgraduate Modular Diploma or Degree Course

 
ECTS CREDITS 5

 
DEPARTMENT Clinical Pharmacology and Therapeutics

 
DESCRIPTION This unit provides the background and introduction for the management of poisoning of commonly used chemicals and pharmaceuticals. It will include a description of the commonly used diagnostic tools and how to make management choices including use of antidotes in the context of best research evidence and clinical expertise, taking into account an individual patient views and needs. The management in cases of paediatric toxicology will also be covered.

Study-unit Aims:

This study-unit aims to:
- Provide candidates with the knowledge needed to be able to interpret and apply the diagnostic tools and management plans in treating poisoned patient;
- Review triage principles in the context of the poisoned patient (including the paediatric patient), making the initial evaluation of such patient;
- Appreciate the toxicity effects of commonly used chemicals and pharmaceuticals and accurately identify the features of poisoning by such substances;
- Provide candidates with the knowledge needed in the selection of antidotes in urgency and supply procedures.

Learning Outcomes:

1. Knowledge & Understanding
By the end of the study-unit the student will be able to:

- Evaluate the management of overdose with commonly used pharmaceuticals;
- Correlate symptoms with the possible identification of commonly used pharmaceuticals;
- Integrate the use of diagnostic tools and management methods for the diagnosis and treatment of poisoned patients including the paediatric patient;
- formulate appropriate questions to use when intervening to treat poisoned patients;
- Analyse the relevance of different management options in the context of specific groups of poisoned patients, including use of antidotes;
- Translate their knowledge of medical toxicology and the related principles of diagnosis and management into their clinical arena.

2. Skills
By the end of the study-unit the student will be able to:

- Interpret symptoms of poisoning with the identification of commonly used pharmaceuticals;
- Interpret the results of diagnostic tools and apply correct methods for the diagnosis and management of poisoned patients including the paediatric patient;
- Plan appropriate questions to use when intervening to treat poisoned patients;
- Plan the correct management options, including use of antidotes in the context of specific groups of poisoned patients;
- Apply their knowledge of medical toxicology and the related principles of diagnosis and management into their clinical arena;
- Formulate plans for management of patients in relation to poisoning.

Main Text/s and any supplementary readings:

Main readings

- Klaassen, Curtis D. Casarett and Doull's toxicology: the basic science of poisons. 9th edition New York McGraw-Hill Education 2019 ISBN 978-1-259-86374-5
- Lewis Nelson, Robert Hoffman,Mary Ann Howland, Neal Lewin), Lewis Goldfrank, Silas W Smith Goldfrank's toxicologic emergencies. 11th edition New York McGraw Hill Medical 2019 ISBN 978-1259859618 (Health Sciences Library Reference RA1224.5.G6 2019 )
- Curtis Klaassen, John Watkins. Casarett & Doull's Essentials of Toxicology, Third Edition. 2015. McGraw Hill ISBN 978-0071847087
- Lindsay Murray MBBS FACEM, Mark Little MBBS FACEM MPH&TM DTM&H IDHA, Ovidiu Pascu MD FACEM, Kerry Anne Hoggett MBBS GCertClinTox FACEM. Toxicology Handbook 2015 Churchill Livngsston ISBN 978-0729542241(Health Sciences library RA1215.T683 2015).

Supplementary readings

- Ira S Richards Marie Bourgeois. Principles and Practice of Toxicology in Public Health - 2nd edition 2014 Jones and Bartlett Publishers ISBN 9781449645267
- Kareen E Stine Thomas M Brown Principles of Toxicology 2015 CRS Press ISBN 9781466503427 (main library RA1211 .S75 2015)
- Abby Calvin Textbook of Pharmacology and Toxicology. 2016 Syraword Publishing House ISBN 978-1682861912
- Lester M. Haddad, Michael W. Shannon, James F. Winchester Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose 4th Edition 2007 Sunders ISBN 978-0721606934.

Journals (available in Main Library and Health Sciences Library and as e-journals subscribed by UM)

Toxicology
Pharmacology & toxicology
Clinical toxicology
Clinical toxicology
International journal of toxicology
Critical reviews in toxicology
Toxicology and applied pharmacology.

 
STUDY-UNIT TYPE Lecture and Independent Study

 
METHOD OF ASSESSMENT
Assessment Component/s Assessment Due Resit Availability Weighting
Presentation (15 Minutes) SEM2 Yes 20%
Assignment SEM2 Yes 80%

 
LECTURER/S Jeffrey Bonnici
Robert Chircop
Janet Mifsud (Co-ord.)

 
The University makes every effort to ensure that the published Courses Plans, Programmes of Study and Study-Unit information are complete and up-to-date at the time of publication. The University reserves the right to make changes in case errors are detected after publication.
The availability of optional units may be subject to timetabling constraints.
Units not attracting a sufficient number of registrations may be withdrawn without notice.
It should be noted that all the information in the description above applies to study-units available during the academic year 2021/2. It may be subject to change in subsequent years.

https://www.um.edu.mt/course/studyunit