| CODE | CPH5404 | ||||||||||||
| TITLE | Clinical Toxicology and Management of Poisoning of Commonly Used Pharmaceuticals 2 | ||||||||||||
| UM LEVEL | 05 - Postgraduate Modular Diploma or Degree Course | ||||||||||||
| MQF LEVEL | 7 | ||||||||||||
| ECTS CREDITS | 5 | ||||||||||||
| DEPARTMENT | Clinical Pharmacology and Therapeutics | ||||||||||||
| DESCRIPTION | This unit provides further clinical background in the management of poisoning of more commonly used chemicals and pharmaceuticals. It will include a deeper appraisal of management choices in the context of best research evidence and clinical expertise, decontamination procedures and antidote use (including in the paediatric patient). Study-unit Aims: This study unit aims to: - Deliver further information on the clinical management of overdose of commonly used pharmaceuticals; - Provide candidates with examples of clinical cases which will be used in the application of principles discussed in previous study units (including in the paediatric patient); - Review decontamination principles including techniques to prevent gastrointestinal absorption; prevention of dermal, ophthalmic and inhalational absorption; - Appreciate principles and techniques applied to enhance elimination well as antidotes use in urgency and supply procedures. Learning Outcomes: 1. Knowledge & Understanding By the end of the study-unit the student will be able to: - Evaluate the clinical management of overdose of commonly used pharmaceuticals; - Integrate the principles discussed in previous study units. examples of clinical cases of poisoning; - Analyse decontamination techniques to prevent gastrointestinal absorption; prevention of dermal, ophthalmic and inhalational absorption; - Translate principles and techniques applied in basic pharmacotoxicology in analysing the use of antidotes (including in the paediatric patient). 2. Skills By the end of the study-unit the student will be able to: - Plan the appropriate clinical management of overdose of commonly used pharmaceuticals; - Apply the principles discussed in previous study units in examples of clinical cases in poisoning; - Formulate decontamination techniques to prevent gastrointestinal absorption; prevention of dermal, ophthalmic and inhalational absorption; - Translate principles and techniques applied in basic pharmacotoxicology in reviewing the use of antidotes (including in the paediatric patient). Main Text/s and any supplementary readings: Main readings - Klaassen, Curtis D. Casarett and Doull's toxicology: the basic science of poisons. 9th edition New York McGraw-Hill Education 2019 ISBN 978-1-259-86374-5 - Lewis Nelson, Robert Hoffman,Mary Ann Howland, Neal Lewin), Lewis Goldfrank, Silas W Smith Goldfrank's toxicologic emergencies. 11th edition New York McGraw Hill Medical 2019 ISBN 978-1259859618 (Health Sciences Library Reference RA1224.5.G6 2019) - Curtis Klaassen, John Watkins. Casarett & Doull's Essentials of Toxicology, Third Edition. 2015. McGraw Hill ISBN 978-0071847087 - Lindsay Murray MBBS FACEM, Mark Little MBBS FACEM MPH&TM DTM&H IDHA, Ovidiu Pascu MD FACEM, Kerry Anne Hoggett MBBS GCertClinTox FACEM. Toxicology Handbook 2015 Churchill Livngsston ISBN 978-0729542241(Health Sciences library RA1215.T683 2015). Supplementary readings - Ira S Richards Marie Bourgeois. Principles and Practice of Toxicology in Public Health - 2nd edition 2014 Jones and Bartlett Publishers ISBN 9781449645267 - Kareen E Stine Thomas M Brown Principles of Toxicology 2015 CRS Press ISBN 9781466503427 (main library RA1211 .S75 2015) - Abby Calvin Textbook of Pharmacology and Toxicology. 2016 Syraword Publishing House ISBN 978-1682861912 - Lester M. Haddad, Michael W. Shannon, James F. Winchester Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose 4th Edition 2007 Sunders ISBN 978-0721606934. Journals (available in Main Library and Health Sciences Library and as e-journals subscribed by UM) Toxicology Pharmacology & toxicology Clinical toxicology Clinical toxicology International journal of toxicology Critical reviews in toxicology Toxicology and applied pharmacology. |
||||||||||||
| STUDY-UNIT TYPE | Lecture and Independent Study | ||||||||||||
| METHOD OF ASSESSMENT |
|
||||||||||||
| LECTURER/S | Muhammad Elamin Ophir Lavon Jeffrey Bonnici Robert Chircop Davide Lonati Janet Mifsud (Co-ord.) Mark Zammit |
||||||||||||
|
The University makes every effort to ensure that the published Courses Plans, Programmes of Study and Study-Unit information are complete and up-to-date at the time of publication. The University reserves the right to make changes in case errors are detected after publication.
The availability of optional units may be subject to timetabling constraints. Units not attracting a sufficient number of registrations may be withdrawn without notice. It should be noted that all the information in the description above applies to study-units available during the academic year 2025/6. It may be subject to change in subsequent years. |
|||||||||||||