Study-Unit Description

Study-Unit Description


CODE IFS0703

 
TITLE Introduction to Clinical Biochemistry 1

 
UM LEVEL 00 - Mod Pre-Tert, Foundation, Proficiency & DegreePlus

 
MQF LEVEL 4

 
ECTS CREDITS 6

 
DEPARTMENT Medical and Dental Sciences

 
DESCRIPTION This study unit focuses on an introductory overview of the molecules of life of relevance and importance to biochemistry. The study unit deals with the study of the chemical processes in living organisms including the structures and functions of cellular components such as proteins, carbohydrates and lipids. It also covers acid and bases, biological buffers, glycolysis, gluconeogenesis, electron transport and oxidative phosphorylation. It describes how enzyme activity is regulated to reflect the physiological state of the organism. The clinical aspects of each topic are discussed.

Study-unit Aims:

1. To introduce important biochemistry concepts such as homeostasis, acid-base balance and buffering;
2. To provide an introduction to the chemistry of proteins, carbohydrates and lipids;
3. To understand the pathways of glycolysis, gluconeogenesis and the citric acid cycle;
4. To discuss clinical aspects of biochemistry.

Learning Outcomes:

1. Knowledge & Understanding
By the end of the study-unit the student will be able to:

1. Outline carbohydrate pathways and understand how these are part of a network;
2. Characterise different types of biomolecules;
3. Understand the clinical aspects of biochemistry with respect to acid-base balance, nutrition, vitamins and protein misfolding.

2. Skills
By the end of the study-unit the student will be able to:

1. Explain how the body maintains a constant acid-base balance through different buffering systems;
2. Explain how glucose is synthesised or broken down according to the needs of the body;
3. Explain how the body converts dietary and stored fuel into energy.

Main Text/s and any supplementary readings:

- Lippincott's Illustrated reviews: Biochemistry Fourth Edition. Authors: Pamela C Champe, Richard A Harvey, Denise R Ferrier. Publisher: Lippincott Williams & Wilkins. ISBN: 0781769604.
- Marshall, W.J., Lapsley. M., Day, A., and Shipman, K. (2020). Clinical Chemistry (9th Edition). Elsevier. ISBN: 0702079367.

 
ADDITIONAL NOTES Pre-requisite: As per Legal Notice 115 of Education Act (2009)

This study-unit is offered only to the Certificate in Foundation Studies students.

Please note that a pass in the Examination component is obligatory for an overall pass mark to be awarded.

 
STUDY-UNIT TYPE Lecture and Independent Study

 
METHOD OF ASSESSMENT
Assessment Component/s Assessment Due Sept. Asst Session Weighting
Oral and Written Exercises SEM1 No 10%
Progress Test SEM1 No 20%
Examination [See Add. Notes] (2 Hours) SEM1 Yes 70%

 
LECTURER/S Nadine Sciortino

 

 
The University makes every effort to ensure that the published Courses Plans, Programmes of Study and Study-Unit information are complete and up-to-date at the time of publication. The University reserves the right to make changes in case errors are detected after publication.
The availability of optional units may be subject to timetabling constraints.
Units not attracting a sufficient number of registrations may be withdrawn without notice.
It should be noted that all the information in the description above applies to study-units available during the academic year 2023/4. It may be subject to change in subsequent years.

https://www.um.edu.mt/course/studyunit