| CODE | MDS2008 | ||||||||
| TITLE | Pathology | ||||||||
| UM LEVEL | 02 - Years 2, 3 in Modular Undergraduate Course | ||||||||
| MQF LEVEL | 5 | ||||||||
| ECTS CREDITS | 4 | ||||||||
| DEPARTMENT | Faculty of Medicine and Surgery | ||||||||
| DESCRIPTION | This study-unit provides a solid grounding in general aspects of diseases processes through a series of lectures, followed by interactive small group tutorials and practicals. It provides training in the recognition and interpretation of pathological changes and diagnostics in order for the student to understand specific clinical diagnostic problems. The lectures deal with cell adaptations and cell death, wound healing, neoplasia, disorders of metabolism and homeostasis, nutritional and environmental diseases and genetic investigation of the genome. Tutorials introduce the student to the role of the cytology and histopathology laboratories in the diagnosis and management of disease while others deal with immune diseases and the clinical aspects of cytogenetics and molecular biology. The laboratory based practical sessions emphasise the important core aspects of cell injury, inflammation, cardiovascular disorders and neoplasia. Study-unit Aims: To provide a foundation for understanding the pathogenesis of disease and the role of various pathology in the diagnosis and management of patients. Learning Outcomes: 1. Knowledge & Understanding: By the end of the study-unit the student will be able to: - Classify disease based on aetiology and pathogenesis; - Define specific pathological terms; - Discuss the effect of injury and the response of cells and tissues; - Describe the basic pathological mechanisms in inflammation, ischaemia, immunity;homeostasis, cytogenetics and molecular biology; - Describe the characteristics of neoplastic cells and the principles/molecular basis of carcinogenesis and tumour development and progression; - Discuss the pathogenesis of vascular disease; - Delineate the various types of abnormal cellular accumulations; - Explain the role of nutritional imbalances in the causation of disease; - Describe the role of environmental factors in the pathogenesis of disease; - Describe the type of laboratory tests available for clinical use; - Explain the problems in obtaining specimen material for clinical diagnosis; - State the problems encountered in laboratory processing that affect test results. 2. Skills: By the end of the study-unit the student will be able to: - Distinguish alterations in chromosome structure in relation to specific syndromes; - Explain how karyotpe analysis is performed; - Recognise different classes of disease on gross and microscopic specimens; - Distinguish between benign and malignant tumours in terms of gross and microscopic morphology and clinical behaviour; - Interpret common symptoms and signs in terms of possible underlying pathology; - Identify risk factors for disease; - Identify and distinguish between the clinical laboratory disciplines; - Describe the principles underlying diagnostic laboratory tests; - Correlate the use of simple diagnostic laboratory tests with clinical and morphological features of disease. Main Text/s and any supplementary readings: Recommended Books: Systematic Pathology (and Haematology): - Muir’s Textbook of Pathology, Ed by C S Herrington, 16th Edition, CRC Press, 2020. ISBN-13: 978-0367146726 ISBN-10: 036714672X (available both digitally and in paper format) OR - Underwood’s Pathology: A Clinical Approach, SB Cross, 7th Edition, Churchill Livingstone, 2019. ISBN-13: 978-0702072123 ISBN-10: 0702072125 (available both digitally and in paper format) OR - Robbins Basic Pathology, V Kumar, A K Abbas, JC Aster, 10th Edition, Saunders, 2017. ISBN-13: 978-0323353175 ISBN-10: 0323353177 (available both digitally and in paper format) AND Additional Resources: Systematic Pathology (and Haematology): - Pathology Illustrated, R Reid, F Roberts, E MacDuff, 8th Edition, Churchill Livingstone, 2018. ISBN-13: 978-0702072062 ISBN-10: 0702072060 - Robbins and Cotran Review of Pathology, EC Klatt, V Kumar, 4th Edition, Saunders, 2014. ISBN: 1455751553 / 978-1455751556. Reference Texts: - Robbins & Cotran Pathologic Basis of Disease, V Kumar, A K Abbas, J C Aster, 9e, 10th Edition, Saunders, 2020. ISBN-13: 978-0323531139 ISBN-10: 032353113X Various Internet Resources are available for Pathology See http://library.med.utah.edu/WebPath/webpath.html |
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| STUDY-UNIT TYPE | Lectures, Practical and Tutorials | ||||||||
| METHOD OF ASSESSMENT |
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| LECTURER/S | Isabella Borg Gerald C. Buhagiar Alexander Gatt David Pisani |
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The University makes every effort to ensure that the published Courses Plans, Programmes of Study and Study-Unit information are complete and up-to-date at the time of publication. The University reserves the right to make changes in case errors are detected after publication.
The availability of optional units may be subject to timetabling constraints. Units not attracting a sufficient number of registrations may be withdrawn without notice. It should be noted that all the information in the description above applies to study-units available during the academic year 2023/4. It may be subject to change in subsequent years. |
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