Study-Unit Description

Study-Unit Description


TITLE Experimental Haematology

LEVEL 05 - Postgraduate Modular Diploma or Degree Course


DEPARTMENT Faculty of Medicine and Surgery

DESCRIPTION The teaching programme is intended to address Molecular Patho-Physiology of Blood and Body Defence Mechanisms. It includes an in depth review of fundamental issues on the science of blood and stem cell biology, particular properties of each blood cell lineage, Haemoglobin, inflammation and immunity, and coagulation. In addition, the regulation of Hematopoiesis at the level of gene expression, transcription factor lineage commitment and growth factor induced proliferation is part of the study unit. Disregulation of these processes leading to the Pathology of Blood Disorders (Anaemia, MDP, MDS, Leukemia) will be reviewed extensively and current achievements in the search for therapeutics will be discussed in this section of the study unit. Each topic will be studied at advanced level emphasizing experimental research methodology, with reference to clinical significance. Contemporary issues in haematology research are given prominence.

Learning Objectives

By the end of the study unit the student should have a critical understanding of the continuous generation of blood cells as per physiological demand; how this is achieved and regulated; and malfunction of the heamatopoietic regulation process leading to disease. The students shall be fluent in discussing current research in the Pathology of Blood and have an overview of the search for therapeutics.

Reading List

1. Mechanisms in Hematology
Lyonel G Israels and Esther D Israels

2. Robbins and Cotran Pathologic Basis of Disease
Vinay Kumar, Nelso Fausto, Abul Abbas
Publisher: Philadelphia, Pa. ; Elsevier Saunders, c2005.
ISBN: 0721601871

STUDY-UNIT TYPE Lecture and Tutorial

Assessment Component/s Assessment Due Resit Availability Weighting
Assignment SEM2 Yes 10%
Assignment SEM2 Yes 10%
Examination (2 Hours) SEM2 Yes 40%
Examination (2 Hours) SEM2 Yes 40%

LECTURER/S Alex E. Felice
Godfrey Grech

The University makes every effort to ensure that the published Courses Plans, Programmes of Study and Study-Unit information are complete and up-to-date at the time of publication. The University reserves the right to make changes in case errors are detected after publication.
The availability of optional units may be subject to timetabling constraints.
Units not attracting a sufficient number of registrations may be withdrawn without notice.
It should be noted that all the information in the description above applies to study-units available during the academic year 2020/1. It may be subject to change in subsequent years.